Next-generation sequencing

Česká verzia

Authors: Eva Froňková
Authors place of work: Laboratoř molekulární genetiky CLIP, Klinika dětské hematologie a onkologie 2. LF UK a FN Motol, Praha
Published in the journal: Čes.-slov. Patol., 49, 2013, No. 3, p. 129-132
Category: Přehledový článek

Summary

Next generation or massive parallel sequencing (MPS) is a rapidly advancing method in molecular genetics that will bring significant changes in the personalized medicine field. In this review we briefly describe major types of MPS, including whole-genome, -exome, -transcriptome and amplicon sequencing. We also present an overview of the advantages, drawbacks and possible applications of sequencing technologies available in the Czech Republic.

Keywords:
massive parallel sequencing – next generation sequencing – whole-genome – exome – transcriptome – amplicon sequencing

Zdroje

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