Unusual histopathological picture of acute lung injury in different stages of resorption with predominance of organizing pneumonia in a young man with influenza A (H1N1)

Česká verzia

Authors: Daniel Farkaš ¹; Radoslav Matěj ²; Marián Švajdler ml. ³; Marcela Sluková ⁴; Jana Seligová ⁵; Lucia Fröhlichová ⁶; Silvia Farkašová Iannaccone ⁷; Vlasta Vyhnálková ¹; Alžbeta Ginelliová ^1,7
Authors place of work: Úrad pre dohľad nad zdravotnou starostlivosťou, SLaPA pracovisko, Košice ¹; Oddělení patologie a molekulární medicíny, Thomayerova nemocnice, Praha ²; Šiklův ústav patologie, Univerzita Karlova v Praze, Lékařská fakulta v Plzni a Fakultní nemocnice Plzeň ³; Oddelenie anesteziológie a intenzívnej medicíny, Univerzitná nemocnica Louisa Pasteura, Košice ⁴; Regionálny úrad verejného zdravotníctva, Košice ⁵; Oddelenie patológie, Univerzitná nemocnica Louisa Pasteura, Košice ⁶; Ústav súdneho lekárstva UPJŠ LF, Košice ⁷
Published in the journal: Čes.-slov. Patol., 53, 2017, No. 1, p. 38-42
Category: Původní práce

Summary

In this case report the authors describe histomorphological findings of acute lung injury with laboratory-confirmed influenza type A(H1N1) pneumonia leading to the death of a 30 year-old unvaccinated man after 27 days of hospitalisation. Histologically all three types of acute lung injuries were unusually present (diffuse alveolar damage, acute interstitial pneumonia, organizing pneumonia) in different phases of resorption and reparation with transition to extensive fibrosis.

Keywords:
influenza – organizing pneumonia – fibrosis – pneumocytes hyperregeneration

Zdroje

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