Primární rakovina žlučníku diagnoastikovaná pooperačně po elektivní a hospitalizační cholecystektomii

Úvod:
Rakovina žlučníku je vzácný nádor s vysokou mortalitou a špatnou prognózou. Většinou koreluje s cholelitiázou a častěji se prezentuje u starších pacientů a u žen. Tento nádor je málokdy diagnostikován před operací kvůli indolentní progresi nádoru.

Metody:
Byly prozkoumány hospitalizační a chirurgické záznamy našeho chirurgického oddělení z období od ledna 1992 do prosince 2001. Hledáni byli pacienti, kteří podstoupili cholecystektomii. Dále byly studovány histopatologické nálezy a pomocí zmrzlé tkáně byli identifikováni pacienti s diagnózou rakoviny žlučníku stanovené po operaci, nikoli během operace.

Výsledky:
V období 1992– 2001 proběhlo celkem 1 536 cholecystektomií a nalezeno bylo 14 případů rakoviny žlučníku diagnostikovaných pooperativně. Poměr mužů a žen byl 3/ 11 s průměrným věkem 69,4 let. Klinické příznaky byly nespecifické a mortalita dosahovala 57 %.

Závěr:
Ve většině případů je vznik rakoviny žlučníku diagnostikován po cholecystektomii a dokonce i v těchto případech může být v pokročilém stadiu. Prognóza tohoto vzácného nádoru je špatná.

Klíčová slova:
žlučník – nádor – karcinom – cholecystektomie

Autoři: O. Ioannidis ¹; G. Paraskevas ²; I. Varnalidis ³; M. Ntoumpara ¹; L. Tsigkriki ¹; S. Gatzos ¹; S. G. Malakozis ¹; D. Papapostolou ¹; A. Papadopoulou ¹; A. Makrantonakis ¹; N. Makrantonakis ¹
Působiště autorů: First Surgical Department, General Regional Hospital ‘George Papanikolaou’, Thessaloniki, Greece ¹; Department of Anatomy, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece ²; Plastic Surgery Department, General Regional Hospital ‘George Papanikolaou’, Thessaloniki, Greece ³
Vyšlo v časopise: Klin Onkol 2013; 26(1): 31-34
Kategorie: Původní práce

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Obdrženo: 13. 11. 2012

Přijato: 26. 11. 2012

Souhrn

Klíčová slova:
žlučník – nádor – karcinom – cholecystektomie

Zdroje

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