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Confounding by Repetitive Elements and CpG Islands Does Not Explain the Association between Hypomethylation and Genomic Instability

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Vyšlo v časopise: Confounding by Repetitive Elements and CpG Islands Does Not Explain the Association between Hypomethylation and Genomic Instability. PLoS Genet 9(2): e32767. doi:10.1371/journal.pgen.1003333
Kategorie: Viewpoints
prolekare.web.journal.doi_sk: https://doi.org/10.1371/journal.pgen.1003333

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Zdroje

1. LiJ, HarrisRA, CheungSW, CoarfaC, JeongM, et al. (2012) Genomic hypomethylation in the human germline associates with selective structural mutability in the human genome. PLoS Genet 8 (5) e1002692 doi:10.1371/journal.pgen.1002692

2. WatsonCT, GargP, SharpAJ (2013) Comment on “Genomic hypomethylation in the human germline associates with selective structural mutability in the human genome”. PLoS Genet 9: e1003332 doi:10.1371/journal.pgen.1003332

3. MolaroA, HodgesE, FangF, SongQ, McCombieWR, et al. (2011) Sperm methylation profiles reveal features of epigenetic inheritance and evolution in primates. Cell 146 (6) 1029–1041.

4. Hilbe J. (2011) Negative binomial regression. Cambridge, UK: Cambridge University Press. p. 553.

5. McCarrollSA, KuruvillaFG, KornJM, CawleyS, NemeshJ, et al. (2008) Integrated detection and population-genetic analysis of SNPs and copy number variation. Nat Genet 40 (10) 1166–1174.

6. ConradDF, PintoD, RedonR, FeukL, GokcumenO, et al. (2010) Origins and functional impact of copy number variation in the human genome. Nature 464 (7289) 704–712.

7. The Wellcome Trust Case Control Consortium (2010) Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls. Nature 464 (7289) 713–720.

8. The International Schizophrenia Consortium (2008) Rare chromosomal deletions and duplications increase risk of schizophrenia. Nature 455 (7210) 237–241.

9. Pearl J (2000) Causality: models, reasoning, and inference. Cambridge, UK: Cambridge University Press. 384 p.

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Článok vyšiel v časopise

PLOS Genetics

2013 Číslo 2

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Autori: MUDr. Tomáš Ürge, PhD.

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