Achieving the HIV Prevention Impact of Voluntary Medical Male Circumcision: Lessons and Challenges for Managing Programs
Voluntary medical male circumcision (VMMC) is capable of reducing the risk of sexual transmission of HIV from females to males by approximately 60%. In 2007, the WHO and the Joint United Nations Programme on HIV/AIDS (UNAIDS) recommended making VMMC part of a comprehensive HIV prevention package in countries with a generalized HIV epidemic and low rates of male circumcision. Modeling studies undertaken in 2009–2011 estimated that circumcising 80% of adult males in 14 priority countries in Eastern and Southern Africa within five years, and sustaining coverage levels thereafter, could avert 3.4 million HIV infections within 15 years and save US$16.5 billion in treatment costs. In response, WHO/UNAIDS launched the Joint Strategic Action Framework for accelerating the scale-up of VMMC for HIV prevention in Southern and Eastern Africa, calling for 80% coverage of adult male circumcision by 2016. While VMMC programs have grown dramatically since inception, they appear unlikely to reach this goal. This review provides an overview of findings from the PLOS Collection “Voluntary Medical Male Circumcision for HIV Prevention: Improving Quality, Efficiency, Cost Effectiveness, and Demand for Services during an Accelerated Scale-up.” The use of devices for VMMC is also explored. We propose emphasizing management solutions to help VMMC programs in the priority countries achieve the desired impact of averting the greatest possible number of HIV infections. Our recommendations include advocating for prioritization and funding of VMMC, increasing strategic targeting to achieve the goal of reducing HIV incidence, focusing on programmatic efficiency, exploring the role of new technologies, rethinking demand creation, strengthening data use for decision-making, improving governments' program management capacity, strategizing for sustainability, and maintaining a flexible scale-up strategy informed by a strong monitoring, learning, and evaluation platform.
Vyšlo v časopise:
Achieving the HIV Prevention Impact of Voluntary Medical Male Circumcision: Lessons and Challenges for Managing Programs. PLoS Med 11(5): e32767. doi:10.1371/journal.pmed.1001641
Kategorie:
Collection Review
prolekare.web.journal.doi_sk:
https://doi.org/10.1371/journal.pmed.1001641
Souhrn
Voluntary medical male circumcision (VMMC) is capable of reducing the risk of sexual transmission of HIV from females to males by approximately 60%. In 2007, the WHO and the Joint United Nations Programme on HIV/AIDS (UNAIDS) recommended making VMMC part of a comprehensive HIV prevention package in countries with a generalized HIV epidemic and low rates of male circumcision. Modeling studies undertaken in 2009–2011 estimated that circumcising 80% of adult males in 14 priority countries in Eastern and Southern Africa within five years, and sustaining coverage levels thereafter, could avert 3.4 million HIV infections within 15 years and save US$16.5 billion in treatment costs. In response, WHO/UNAIDS launched the Joint Strategic Action Framework for accelerating the scale-up of VMMC for HIV prevention in Southern and Eastern Africa, calling for 80% coverage of adult male circumcision by 2016. While VMMC programs have grown dramatically since inception, they appear unlikely to reach this goal. This review provides an overview of findings from the PLOS Collection “Voluntary Medical Male Circumcision for HIV Prevention: Improving Quality, Efficiency, Cost Effectiveness, and Demand for Services during an Accelerated Scale-up.” The use of devices for VMMC is also explored. We propose emphasizing management solutions to help VMMC programs in the priority countries achieve the desired impact of averting the greatest possible number of HIV infections. Our recommendations include advocating for prioritization and funding of VMMC, increasing strategic targeting to achieve the goal of reducing HIV incidence, focusing on programmatic efficiency, exploring the role of new technologies, rethinking demand creation, strengthening data use for decision-making, improving governments' program management capacity, strategizing for sustainability, and maintaining a flexible scale-up strategy informed by a strong monitoring, learning, and evaluation platform.
Zdroje
1. BaileyRC, MosesS, CoretteBP, AgotK, MacleanI, et al. (2007) Male circumcision for HIV prevention in young men in Kisumu, Kenya: a randomized controlled trial. Lancet 369: 643–656.
2. AuvertB, TaljaardD, LagardeE, Sobngwi-TambekouJ, SittaR, et al. (2005) Randomized, controlled intervention trial of male circumcision for reduction of HIV infection risk: the ANRS 1265 Trial. PLoS Med 2: e298.
3. GrayRH, KigoziG, SerwaddaD, MakumbiF, WatyaS, et al. (2007) Male circumcision for HIV prevention in men in Rakai, Uganda: a randomised trial. Lancet 369: 657–666.
4. WeissHA, QuiqleyMA, HayesRJ (2000) Male circumcision and risk of HIV infection in sub-Saharan Africa: a systematic review and meta-analysis. AIDS 14: 2361–2370.
5. WHO, UNAIDS (2007) New data on male circumcision and HIV prevention: Policy and programme implications. WHO/UNAIDS Technical Consultation on Male Circumcision and HIV Prevention: Research Implications for Policy and Programming. Geneva: WHO.
6. WHO (2011) Joint Strategic Action Framework to Accelerate the Scale-Up of Voluntary Medical Male Circumcision for HIV Prevention in Eastern and Southern Africa, 2012-2016. Geneva: WHO.
7. NjeuhmeliE, ForsytheS, ReedJ, OpuniM, BollingerL, et al. (2011) Voluntary medical male circumcision: modeling the impact and cost of expanding male circumcision for HIV prevention in eastern and southern Africa. PLoS Med 8: e1001132.
8. HankinsC, ForsytheS, NjeuhmeliE (2011) Voluntary medical male circumcision: an introduction to the cost, impact, and challenges of accelerated scaling up. PLoS Med 8: e1001127.
9. Herman-Roloff A, Bailey R, Agot K, Ndinya-Achola J (2010) Medical male circumcision for HIV prevention in Kenya: a study of service provision and adverse events [abstract]. XVIII International AIDS Conference; Vienna, Austria; 18–23 July 2010. Available: http://www.iasociety.org/Abstracts/A200736968.aspx. Accessed 15 October 2013.
10. JenningsL, BertrandJ, RechD, HarveySA, HatzoldK, et al. (2014) Quality of voluntary medical male circumcision services during scale-up: a comparative process evaluation in Kenya, South Africa, Tanzania and Zimbabwe. PLoS ONE 9: e79524.
11. RechD, SpyrelisA, FradeS, PerryL, FarrellM, et al. (2014) Implications of the fast-evolving scale-up of adult voluntary medical male circumcision for quality of services in South Africa. PLoS ONE 9: e80577.
12. RechD, BertrandJT, ThomasN, FarrellM, ReedJ, et al. (2014) Surgical efficiencies and quality in the performance of voluntary medical male circumcision procedures in Kenya, South Africa, Tanzania, and Zimbabwe. PLoS ONE 9: e84271.
13. Onyango T (2011) Male Circumcision Consortium, Monitoring and Evaluation Office.
14. Djimeu Wouabe E (2013) Scoping report on interventions for increasing the demand for voluntary medical male circumcision. Washington (D.C.): International Initiative for Impact Evaluation (3IE).
15. MacintyreK, AndrinopoulosK, MosesN, BornsteinM, OchiengA, et al. (2014) Attitudes, perceptions and potential uptake of male circumcision among older men in Turkana County, Kenya using qualitative methods. PLoS ONE 9: e83998.
16. Herman-RoloffA, OtienoN, AgotK, Ndinya-AcholaJ, BaileyRC (2011) Acceptability of medical male circumcision among uncircumcised men in Kenya one year after the launch of the national male circumcision program. PLoS ONE 6: e19814.
17. WestercampN, BaileyRC (2007) Acceptability of male circumcision for prevention of HIV/AIDS in sub-Saharan Africa: a review. AIDS Behav 11: 341–355.
18. GasasiraRA, SarkerM, TsagueL, NsanzimanaS, GwizaA, et al. (2012) Determinants of circumcision and willingness to be circumcised by Rwandan men, 2010. BMC Public Health 12: 134.
19. WestercampM, AgotKE, Ndinya-AcholaJ, BaileyRC (2012) Circumcision preference among women and uncircumcised men prior to scale-up of male circumcision for HIV prevention in Kisumu, Kenya. AIDS Care 24: 157–166.
20. Plotkin MK, Curran J, Mziray K, Prince H, Mahler J, et al.. (2011) The unpeeled mango: a qualitative assessment of views and preferences of voluntary medical male circumcision in Iringa Region, Tanzania. Dar es Salaam, Tanzania: Jhpiego.
21. HatzoldK, MavhuW, JasiP, ChatoraK, CowanFM, et al. (2014) Barriers and motivators to voluntary medical male circumcision uptake among different age groups of men in Zimbabwe: results from a mixed methods study. PLoS ONE 9: e85051.
22. Adamu AshengoT, HatzoldK, MahlerH, RockA, KanagatN, et al. (2014) Voluntary medical male circumcision (VMMC) in Tanzania and Zimbabwe: service delivery intensity and modality and their influence on the age of clients. PLoS ONE 9: e83642.
23. PlotkinM, CastorD, MzirayH, KüverJ, MpuyaE, et al. (2013) “Man, what took you so long?” Social and individual factors affecting adult attendance at voluntary medical male circumcision services in Tanzania. Glob Health Sci Pract 1: 108–116.
24. BollingerL, AdesinaA, ForsytheS, GodboleR, ReubenE, et al. (2014) Cost drivers for voluntary medical male circumcision using primary source data from sub-Saharan Africa. PLoS ONE 9: e84701.
25. MenonV, GoldE, GodboleR, CastorD, MahlerH, et al. (2014) Costs and impacts of scaling up voluntary medical male circumcision in Tanzania. PLoS ONE 9: e83925.
26. BrattJH, ZyamboZ (2013) Comparing direct costs of facility-based Shang Ring provision versus a standard surgical technique for voluntary medical male circumcision in Zambia. J Acquir Immune Defic Syndr 63: e109–112.
27. DuffyK, GalukandeM, WoodingN, DeaM, CoutinhoA (2013) Reach and cost-effectiveness of the PrePex device for safe male circumcision in Uganda. PLoS ONE 8: e63134.
28. NjeuhmeliE, KripkeK, HatzoldK, ReedJ, EdgilD, et al. (2014) Cost analysis of integrating the PrePex medical device into a voluntary medical male circumcision program in Zimbabwe. PLoS ONE 9: e82533.
29. MavhuW, FradeS, YonghoA, FarrellM, HatzoldK, et al. (2014) Provider attitudes toward the voluntary medical male circumcision scale-up in Kenya, South Africa, Tanzania and Zimbabwe. PLoS ONE 9: e82911.
30. PerryL, RechD, MavhuW, FradeS, MachakuMD, et al. (2014) Work experience, job-fulfillment and burnout among VMMC providers in Kenya, South Africa, Tanzania and Zimbabwe. PLoS ONE 9: e84215.
31. (2008) Avahan—The India AIDS Initiative: The business of HIV prevention at scale. New Delhi: Bill & Melinda Gates Foundation.
32. KikayaV, SkolnikL, GarcíaMC, NkonyanaJ, CurranK, et al. (2014) Voluntary medical male circumcision programs can address low HIV testing and counseling usage and ART enrollment among young men: lessons from Lesotho. PLoS ONE 9: e83614.
33. WHO (2010) Considerations for implementing models for optimizing the volume and efficiency of male circumcision services. Field testing edition. Geneva: WHO.
34. SgaierSK, ClaesonM, GilksC, RameshBM, GhysPD, et al. (2012) Knowing your HIV/AIDS epidemic and tailoring an effective response: how did India do it? Sex Transm Infect 88: 240–249.
35. BertrandJT, RechD, Omondi AdudaD, FradeS, LoolpapitM, et al. (2014) Systematic monitoring of voluntary medical male circumcision scale-up: adoption of efficiency elements in Kenya, South Africa, Tanzania, and Zimbabwe. PLoS ONE 9: e82518.
36. (2013) Micro-planning in peer led outreach programs—a handbook. New Delhi: Bill & Melinda Gates Foundation.
37. SgaierSK, RamakrishnanA, DhingraN, WadhwaniA, AlexanderA, et al. (2013) How the Avahan HIV prevention program transitioned from the Gates Foundation to the Government of India. Health Affairs 32: 1265–1273.
38. WHO/AFRO (2013) Progress in scaling up voluntary medical male circumcision for HIV prevention in East and Southern Africa, January – December 2012. Brazzaville: WHO/AFRO.
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