Access to antiretroviral therapy in HIV-infected children aged 0–19 years in the International Epidemiology Databases to Evaluate AIDS (IeDEA) Global Cohort Consortium, 2004–2015: A prospective cohort study
In a research article, Valériane Leroy and colleagues study access to antiretroviral therapy in a large population of children and adolescents with HIV-1 infection across 6 regions, and identify priorities for improving access to treatment.
Vyšlo v časopise:
Access to antiretroviral therapy in HIV-infected children aged 0–19 years in the International Epidemiology Databases to Evaluate AIDS (IeDEA) Global Cohort Consortium, 2004–2015: A prospective cohort study. PLoS Med 15(5): e32767. doi:10.1371/journal.pmed.1002565
Kategorie:
Research Article
prolekare.web.journal.doi_sk:
https://doi.org/10.1371/journal.pmed.1002565
Souhrn
In a research article, Valériane Leroy and colleagues study access to antiretroviral therapy in a large population of children and adolescents with HIV-1 infection across 6 regions, and identify priorities for improving access to treatment.
Zdroje
1. Joint United Nations Programme on HIV/AIDS. UNAIDS data 2017. Geneva: Joint United Nations Programme on HIV/AIDS; 2017 [cited 2018 Mar 16]. Available from: http://www.unaids.org/sites/default/files/media_asset/2017_data-book_en.pdf.
2. Newell ML, Coovadia H, Cortina Borja M, Rollins N, Gaillard P, Dabis F,et al. Mortality of infected and uninfected infants born to HIV-infected mothers in Africa: a pooled analysis. Lancet. 2004;364:1236–43. doi: 10.1016/S0140-6736(04)17140-7 15464184
3. Violari A, Cotton MF, Gibb DM, Babiker AG, Steyn J, Madhi SA, et al. Early antiretroviral therapy and mortality among HIV-infected infants. N Engl J Med. 2008;359:2233–44. doi: 10.1056/NEJMoa0800971 19020325
4. World Health Organization. Consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection: recommendations for a public health approach. Geneva: World Health Organization; 2013 [cited 2018 Mar 16]. Available from: http://www.who.int/hiv/pub/guidelines/arv2013/en/index.html.
5. World Health Organization, Joint United Nations Programme on HIV/AIDS, United Nations Children’s Fund. Towards universal access: scaling up priority HIV/AIDS interventions in the health sector. Progress report 2010. Geneva: World Health Organization; 2010 [cited 2018 Mar 16]. Available from: http://whqlibdoc.who.int/publications/2010/9789241500395_eng.pdf.
6. World Health Organization. Consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection: recommendations for a public health approach—second edition. Geneva: World Health Organization; 2016 [cited 2018 Mar 16]. Available from: http://www.who.int/hiv/pub/arv/arv-2016/en/.
7. Joint United Nations Programme on HIV/AIDS. On the fast track to an AIDS-free generation. Geneva: Joint United Nations Programme on HIV/AIDS; 2015 [cited 2018 Mar 16]. Available from: http://www.unaids.org/sites/default/files/media_asset/GlobalPlan2016_en.pdf.
8. Joint United Nations Programme on HIV/AIDS. The 90-90-90: an ambitious treatment target to help end the AIDS epidemic. Geneva: Joint United Nations Programme on HIV/AIDS; 2014 [cited 2018 Apr 6]. Available from: http://www.unaids.org/sites/default/files/media_asset/90-90-90_en.pdf.
9. Chamla D, Mbori-Ngacha D, Newman M, Kellerman SE, Sugandhi N, Rwebembera A, et al. Evidence from the field: missed opportunities for identifying and linking HIV-infected children for early initiation of ART. AIDS. 2013;27(Suppl 2):S139–46.
10. World Health Organization. Antiretroviral therapy of HIV infection in infants and children in resource-limited settings: towards universal access. Recommendations for a public health approach. Geneva: World Health Organization; 2006 [cited 2018Apr 6]. Available from: http://www.who.int/hiv/pub/guidelines/WHOpaediatric.pdf.
11. World Health Organization. Guideline on when to start antiretroviral therapy and on pre-exposure prophylaxis for HIV. Geneva: World Health Organization; 2015 [cited 2018 Mar 16]. Available from: http://apps.who.int/iris/bitstream/10665/186275/1/9789241509565_eng.pdf?ua=1.
12. Scrucca L, Santucci A, Aversa F. Regression modeling of competing risk using R: an in depth guide for clinicians. Bone Marrow Transplant. 2010;45:1388–95. doi: 10.1038/bmt.2009.359 20062101
13. Li J, Scheike TH, Zhang MJ. Checking Fine and Gray subdistribution hazards model with cumulative sums of residuals. Lifetime Data Anal. 2015;21:197–217. doi: 10.1007/s10985-014-9313-9 25421251
14. Kohl M, Plischke M, Leffondre K, Heinze G. PSHREG: a SAS macro for proportional and nonproportional subdistribution hazards regression. Comput Methods Programs Biomed. 2015;118:218–33. doi: 10.1016/j.cmpb.2014.11.009 25572709
15. Feucht UD, Kinzer M, Kruger M. Reasons for delay in initiation of antiretroviral therapy in a population of HIV-infected South African children. J Trop Pediatr. 2007;53:398–402. doi: 10.1093/tropej/fmm060 17965099
16. Leyenaar JK, Novosad PM, Ferrer KT, Thahane LK, Mohapi EQ, Schutze GE, et al. Early clinical outcomes in children enrolled in human immunodeficiency virus infection care and treatment in Lesotho. Pediatr Infect Dis J. 2010;29:340–5. doi: 10.1097/INF.0b013e3181bf8ecb 20019645
17. Anaky MF, Duvignac J, Wemin L, Kouakoussui A, Karcher S, Touré S, et al. Scaling up antiretroviral therapy for HIV-infected children in Cote d’Ivoire: determinants of survival and loss to programme. Bull World Health Organ. 2010;88:490–9. doi: 10.2471/BLT.09.068015 20616968
18. Leroy V, Malateste K, Rabie H, Lumbiganon P, Ayaya S, Dicko F, et al. Outcomes of antiretroviral therapy in children in Asia and Africa: a comparative analysis of the IeDEA pediatric multiregional collaboration. J Acquir Immune Defic Syndr. 2013;62:208–19. doi: 10.1097/QAI.0b013e31827b70bf 23187940
19. Penazzato M, Revill P, Prendergast AJ, Collins IJ, Walker S, Elyanu PJ, et al. Early infant diagnosis of HIV infection in low-income and middle-income countries: does one size fit all? Lancet Infect Dis. 2014;14:650–5. doi: 10.1016/S1473-3099(13)70262-7 24456814
20. Ciaranello AL, Park J, Ramirez-Avila L, Freedberg KA, Walensky RP, Leroy V. Early infant HIV-1 diagnosis programs in resource-limited settings: opportunities for improved outcomes and more cost-effective interventions. BMC Med. 2011;9:59. doi: 10.1186/1741-7015-9-59 21599888
21. Edmonds A, Feinstein L, Okitolonda V, Thompson D, Kawende B, Behets F. Implementation and operational research: decentralization does not assure optimal delivery of PMTCT and HIV-exposed infant services in a low prevalence setting. J Acquir Immune Defic Syndr. 2015;70:e130–9. doi: 10.1097/QAI.0000000000000781 26262776
22. Hassan AS, Sakwa EM, Nabwera HM, Taegtmeyer MM, Kimutai RM, Sanders EJ, et al. Dynamics and constraints of early infant diagnosis of HIV infection in rural Kenya. AIDS Behav. 2012;16:5–12. doi: 10.1007/s10461-010-9877-7 21213034
23. Geelhoed D, Lafort Y, Chissale E, Candrinho B, Degomme O. Integrated maternal and child health services in Mozambique: structural health system limitations overshadow its effect on follow-up of HIV-exposed infants. BMC Health Serv Res. 2013;13:207. doi: 10.1186/1472-6963-13-207 23758816
24. Coulibaly M, Meda N, Yonaba C, Ouedraogo S, Congo M, Barry M, et al. Missed opportunities for early access to care of HIV-infected infants in Burkina Faso. PLoS ONE. 2014;9:e111240. doi: 10.1371/journal.pone.0111240 25360551
25. Dahourou DL, Amorissani-Folquet M, Coulibaly M, Avit-Edi D, Meda N, Timite-Konan M, et al. Missed opportunities of inclusion in a cohort of HIV-infected children to initiate antiretroviral treatment before the age of two in West Africa, 2011 to 2013. J Int AIDS Soc. 2016;19:20601. doi: 10.7448/IAS.19.1.20601 27015798
26. De Schacht C, Lucas C, Mboa C, Gill M, Macasse E, Dimande SA, et al. Access to HIV prevention and care for HIV-exposed and HIV-infected children: a qualitative study in rural and urban Mozambique. BMC Public Health. 2014;14:1240. doi: 10.1186/1471-2458-14-1240 25467030
27. Ndondoki C, Brou H, Timite Konan M, Oga M, Amani Bosse C, Menan H, et al. Universal HIV screening at postnatal points of care: which public health approach for early infant diagnosis in Côte d’Ivoire? PLoS ONE. 2013;8:e67996. doi: 10.1371/journal.pone.0067996 23990870
28. Phelps BR, Ahmed S, Amzel A, Diallo MO, Jacobs T, Kellerman SE, et al. Linkage, initiation and retention of children in the antiretroviral therapy cascade: an overview. AIDS. 2013;27(Suppl 2):S207–13.
29. Russell S, Zalwango F, Namukwaya S, Katongole J, Muhumuza R, Nalugya R, et al. Antiretroviral therapy and changing patterns of HIV stigmatisation in Entebbe, Uganda. Sociol Health Illn. 2016;38:58–72. doi: 10.1111/1467-9566.12341 26382288
30. Adeniyi VO, Thomson E, Ter Goon D, Ajayi IA. Disclosure, stigma of HIV positive child and access to early infant diagnosis in the rural communities of OR Tambo District, South Africa: a qualitative exploration of maternal perspective. BMC Pediatr. 2015;15:98. doi: 10.1186/s12887-015-0414-8 26306387
31. Neuman M, Obermeyer CM. Experiences of stigma, discrimination, care and support among people living with HIV: a four country study. AIDS Behav. 2013;17:1796–808. doi: 10.1007/s10461-013-0432-1 23479002
32. Maman S, Cathcart R, Burkhardt G, Omba S, Behets F. The role of religion in HIV-positive women’s disclosure experiences and coping strategies in Kinshasa, Democratic Republic of Congo. Soc Sci Med. 2009;68:965–70. doi: 10.1016/j.socscimed.2008.12.028 19136188
33. Manzi M, Zachariah R, Teck R, Buhendwa L, Kazima J, Bakali E, et al. High acceptability of voluntary counselling and HIV-testing but unacceptable loss to follow up in a prevention of mother-to-child HIV transmission programme in rural Malawi: scaling-up requires a different way of acting. Trop Med Int Health. 2005;10:1242–50. doi: 10.1111/j.1365-3156.2005.01526.x 16359404
34. Rosen S, Fox MP. Retention in HIV care between testing and treatment in sub-Saharan Africa: a systematic review. PLoS Med. 2011;8:e1001056. doi: 10.1371/journal.pmed.1001056 21811403
35. Thomson KA, Cheti EO, Reid T. Implementation and outcomes of an active defaulter tracing system for HIV, prevention of mother to child transmission of HIV (PMTCT), and TB patients in Kibera, Nairobi, Kenya. Trans R Soc Trop Med Hyg. 2011;105:320–6. doi: 10.1016/j.trstmh.2011.02.011 21511317
36. Leeper SC, Montague BT, Friedman JF, Flanigan TP. Lessons learned from family-centred models of treatment for children living with HIV: current approaches and future directions. J Int AIDS Soc. 2010;13(Suppl 2):S3.
37. Henwood R, Patten G, Barnett W, Hwang B, Metcalf C, Hacking D, et al. Acceptability and use of a virtual support group for HIV-positive youth in Khayelitsha, Cape Town using the MXit social networking platform. AIDS Care. 2016;28:898–903. doi: 10.1080/09540121.2016.1173638 27098208
38. Goga AE, Singh Y, Singh M, Noveve N, Magasana V, Ramraj T, et al. Enhancing HIV treatment access and outcomes amongst HIV infected children and adolescents in resource limited settings. Matern Child Health J. 2017;21:1–8.
39. Teasdale CA, Alwar T, Chege D, Fayorsey R, Hawken MP, Abrams EJ. Impact of youth and adolescent friendly services on retention of 10–24-year-olds in HIV care and treatment programs in Nyanza, Kenya. J Acquir Immune Defic Syndr. 2016;71:e56–9.
40. Boender TS, Sigaloff KC, Kayiwa J, Musiime V, Calis JC, Hamers RL, et al. Barriers to initiation of pediatric HIV treatment in Uganda: a mixed-method study. AIDS Res Treat. 2012;2012:817506. doi: 10.1155/2012/817506 22400106
41. van Dijk JH, Sutcliffe CG, Munsanje B, Hamangaba F, Thuma PE, Moss WJ. Barriers to the care of HIV-infected children in rural Zambia: a cross-sectional analysis. BMC Infect Dis. 2009;9:169. doi: 10.1186/1471-2334-9-169 19835604
42. Sweat M, Morin S, Celentano D, Mulawa M, Singh B, Mbwambo J, et al. Community-based intervention to increase HIV testing and case detection in people aged 16–32 years in Tanzania, Zimbabwe, and Thailand (NIMH Project Accept, HPTN 043): a randomised study. Lancet Infect Dis. 2011;11:525–32. doi: 10.1016/S1473-3099(11)70060-3 21546309
43. Schlatter AF, Deathe AR, Vreeman RC. The need for pediatric formulations to treat children with HIV. AIDS Res Treat. 2016;2016:1654938. doi: 10.1155/2016/1654938 27413548
44. Penazzato M, Lee J, Capparelli E, Essajee S, Ford N, Ojoo A, et al. Optimizing drugs to reach treatment targets for children and adolescents living with HIV. J Int AIDS Soc. 2015;18:20270. doi: 10.7448/IAS.18.7.20270 26639117
45. Sam-Agudu NA, Folayan MO, Ezeanolue EE. Seeking wider access to HIV testing for adolescents in sub-Saharan Africa. Pediatr Res. 2016;79:838–45. doi: 10.1038/pr.2016.28 26882367
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