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Ibuprofen versus pivmecillinam for uncomplicated urinary tract infection in women—A double-blind, randomized non-inferiority trial


In a multicenter trial, Ingvild Vik and colleagues studied a non-antimicrobial treatment for urinary tract infections in women.


Vyšlo v časopise: Ibuprofen versus pivmecillinam for uncomplicated urinary tract infection in women—A double-blind, randomized non-inferiority trial. PLoS Med 15(5): e32767. doi:10.1371/journal.pmed.1002569
Kategorie: Research Article
prolekare.web.journal.doi_sk: https://doi.org/10.1371/journal.pmed.1002569

Souhrn

In a multicenter trial, Ingvild Vik and colleagues studied a non-antimicrobial treatment for urinary tract infections in women.


Zdroje

1. Colgan R, Williams M. Diagnosis and treatment of acute uncomplicated cystitis. Am Fam Physician. 2011;84(7):771–6. 22010614

2. Stamm WE, McKevitt M, Roberts PL, White NJ. Natural history of recurrent urinary tract infections in women. Rev Infect Dis. 1991;13(1):77–84. 2017637

3. Naber KG, Wullt B, Wagenlehner FM. Antibiotic treatment of uncomplicated urinary tract infection in premenopausal women. Int J Antimicrob Agents. 2011;38(Suppl):21–35.

4. Czaja CA, Scholes D, Hooton TM, Stamm WE. Population-based epidemiologic analysis of acute pyelonephritis. Clin Infect Dis. 2007;45(3):273–80. doi: 10.1086/519268 17599303

5. Flottorp S, Oxman AD, Cooper JG, Hjortdahl P, Sandberg S, Vorland LH. [Guidelines for diagnosis and treatment of acute urinary tract problems in women.] Tidsskr Nor Laegeforen. 2000;120(15):1748–53. 10904661

6. Bollestad M, Grude N, Lindbaek M. A randomized controlled trial of a diagnostic algorithm for symptoms of uncomplicated cystitis at an out-of-hours service. Scand J Prim Health Care. 2015:33(2):57–64. doi: 10.3109/02813432.2015.1041827 25961367

7. Petersen I, Hayward AC. Antibacterial prescribing in primary care. J Antimicrob Chemother. 2007;60(Suppl 1):i43–7.

8. Van Boeckel TP, Gandra S, Ashok A, Caudron Q, Grenfell BT, Levin SA, et al. Global antibiotic consumption 2000 to 2010: an analysis of national pharmaceutical sales data. Lancet Infect Dis. 2014;14(8):742–50. doi: 10.1016/S1473-3099(14)70780-7 25022435

9. Centers for Disease Control and Prevention. Antibiotic resistance threats in the United States, 2013. Atlanta: Centers for Disease Control and Prevention; 2013 [cited 2017 Nov 16]. Available from: http://www.cdc.gov/drugresistance/threat-report-2013/index.html.

10. Wright J, Paauw DS. Complications of antibiotic therapy. Med Clin North Am. 2013;97(4):667–79. doi: 10.1016/j.mcna.2013.02.006 23809719

11. Dancer SJ. How antibiotics can make us sick: the less obvious adverse effects of antimicrobial chemotherapy. Lancet Infect Dis. 2004;4(10):611–9. doi: 10.1016/S1473-3099(04)01145-4 15451489

12. Falagas ME, Kotsantis IK, Vouloumanou EK, Rafailidis PI. Antibiotics versus placebo in the treatment of women with uncomplicated cystitis: a meta-analysis of randomized controlled trials. J Infect. 2009;58(2):91–102. doi: 10.1016/j.jinf.2008.12.009 19195714

13. Bleidorn J, Gagyor I, Kochen MM, Wegscheider K, Hummers-Pradier E. Symptomatic treatment (ibuprofen) or antibiotics (ciprofloxacin) for uncomplicated urinary tract infection?—results of a randomized controlled pilot trial. BMC Med. 2010;8:30. doi: 10.1186/1741-7015-8-30 20504298

14. Gagyor I, Bleidorn J, Kochen MM, Schmiemann G, Wegscheider K, Hummers-Pradier E. Ibuprofen versus fosfomycin for uncomplicated urinary tract infection in women: randomised controlled trial. BMJ. 2015;351:h6544. doi: 10.1136/bmj.h6544 26698878

15. Kronenberg A, Butikofer L, Odutayo A, Muhlemann K, da Costa BR, Battaglia M, et al. Symptomatic treatment of uncomplicated lower urinary tract infections in the ambulatory setting: randomised, double blind trial. BMJ. 2017;359:j4784. doi: 10.1136/bmj.j4784 29113968

16. Schulz KF, Grimes DA. Unequal group sizes in randomised trials: guarding against guessing. Lancet. 2002;359(9310):966–70. doi: 10.1016/S0140-6736(02)08029-7 11918933

17. Watson L, Little P, Moore M, Warner G, Williamson I. Validation study of a diary for use in acute lower respiratory tract infection. Fam Pract. 2001;18(5):553–4. 11604383

18. Little P, Merriman R, Turner S, Rumsby K, Warner G, Lowes JA, et al. Presentation, pattern, and natural course of severe symptoms, and role of antibiotics and antibiotic resistance among patients presenting with suspected uncomplicated urinary tract infection in primary care: observational study. BMJ. 2010;340:b5633. doi: 10.1136/bmj.b5633 20139213

19. Aspevall O, Hallander H, Gant V, Kouri T. European guidelines for urinalysis: a collaborative document produced by European clinical microbiologists and clinical chemists under ECLM in collaboration with ESCMID. Clin Microbiol Infect. 2001;7(4):173–8. 11422238

20. Bergan T, Bruun JN, Digranes A, Lingaas E, Melby KK, Sander J. Susceptibility testing of bacteria and fungi. Report from “the Norwegian Working Group on Antibiotics”. Scand J Infect Dis Suppl. 1997;103:1–36. 9253777

21. Ferry SA, Holm SE, Stenlund H, Lundholm R, Monsen TJ. The natural course of uncomplicated lower urinary tract infection in women illustrated by a randomized placebo controlled study. Scand J Infect Dis. 2004;36(4):296–301. 15198188

22. van der Starre WE, van Dissel JT, van Nieuwkoop C. Treatment duration of febrile urinary tract infections. Curr Infect Dis Rep. 2011;13(6):571–8. doi: 10.1007/s11908-011-0211-y 21882085

23. Lindbaek M, Jensen S, Berild D, Eliassen K, Fetveit A, Grude N, et al. [National guidelines for antibiotic use in primary care.] Oslo: Helsedirektoratet; 2012 Nov. 330 p.

24. Graninger W. Pivmecillinam—therapy of choice for lower urinary tract infection. Int J Antimicrob Agents. 2003;22(Suppl 2):73–8.

25. El Sakka N, Gould IM. Role of old antimicrobial agents in the management of urinary tract infection. Expert Rev Clin Pharmacol. 2016;9(8):1047–56. doi: 10.1080/17512433.2016.1189325 27171243

26. Little P, Moore M, Kelly J, Williamson I, Leydon G, McDermott L, et al. Ibuprofen, paracetamol, and steam for patients with respiratory tract infections in primary care: pragmatic randomised factorial trial. BMJ. 2013;347:f6041. doi: 10.1136/bmj.f6041 24162940

27. Elemraid MA, Thomas MF, Blain AP, Rushton SP, Spencer DA, Gennery AR, et al. Risk factors for the development of pleural empyema in children. Pediatr Pulmonol. 2015;50(7):721–6. doi: 10.1002/ppul.23041 24692118

28. Basille D, Plouvier N, Trouve C, Duhaut P, Andrejak C, Jounieaux V. Non-steroidal anti-inflammatory drugs may worsen the course of community-acquired pneumonia: a cohort study. Lung. 2017;195(2):201–8. doi: 10.1007/s00408-016-9973-1 28005149

29. Le Turnier P, Boutoille D, Joyau C, Veyrac G, Asseray N. Bacterial infections and NSAIDs exposure? Seek septic complications. Eur J Intern Med. 2017;41:e33–4. doi: 10.1016/j.ejim.2017.03.004 28302389

30. Bancos S, Bernard MP, Topham DJ, Phipps RP. Ibuprofen and other widely used non-steroidal anti-inflammatory drugs inhibit antibody production in human cells. Cell Immunol. 2009;258(1):18–28. doi: 10.1016/j.cellimm.2009.03.007 19345936

31. Gagyor I, Haasenritter J, Bleidorn J, McIsaac W, Schmiemann G, Hummers-Pradier E, et al. Predicting antibiotic prescription after symptomatic treatment for urinary tract infection: development of a model using data from an RCT in general practice. Br J Gen Pract. 2016;66(645):e234–40. doi: 10.3399/bjgp16X684361 26965031

32. Little P, Moore MV, Turner S, Rumsby K, Warner G, Lowes JA, et al. Effectiveness of five different approaches in management of urinary tract infection: randomised controlled trial. BMJ. 2010;340:c199. doi: 10.1136/bmj.c199 20139214

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