Immunotoxin Complementation of HAART to Deplete Persisting HIV-Infected Cell Reservoirs
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Immunotoxin Complementation of HAART to Deplete Persisting HIV-Infected Cell Reservoirs. PLoS Pathog 6(6): e32767. doi:10.1371/journal.ppat.1000803
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Zdroje
1. BroderS
2010 The development of antiretroviral therapy and its impact on the HIV-1/AIDS pandemic. Antivir Res 85 1 18
2. ContrerasX
LenasiT
PeterlinBM
2006 HIV latency: present knowledge and future directions. Future Virol 1 733 745
3. GeeraertL
KrausG
PomerantzRJ
2008 Hide-and-seek: the challenge of viral persistence in HIV-1 infection. Annu Rev Med 59 487 501
4. ShenL
SilicianoRF
2008 Viral reservoirs, residual viremia, and the potential of highly active antiretroviral therapy to eradicate HIV infection. J Allergy Clin Immunol 122 22 28
5. StevensonM
2008 Can HIV be cured? Sci Am 299 78 83
6. FauciA
2008 The future of AIDS research. XVII International AIDS Conference; 3–8 August 2008; Mexico City, Mexico. Avaliable: http://www.kaisernetwork.org/health_cast/hcast_index.cfm?display=detail&hc=2912. Accessed 12 May 2010.
7. MarsdenMD
ZackJA
2009 Eradication of HIV: current challenges and new directions. J Antimicrob Chemother 63 7 10
8. RichmanDD
MargolisDM
DelaneyM
GreeneWC
HazudaD
2009 The challenge of finding a cure for HIV infection. Science 323 1304 1307
9. MurphyRL
AutranB
KatlamaC
BruckerG
DebreP
2009 A step ahead on the HIV collaboratory. Science 324 1264 1265
10. StrebhardtK
UllrichA
2008 Paul Ehrlich's magic bullet concept: 100 years of progress. Nat Rev Cancer 8 473 480
11. FuchsH
BachranC
2009 Targeted tumor therapies at a glance. Curr Drug Targ 10 89 93
12. DuvicM
TalpurR
2008 Optimizing denileukin diftitox (Ontak (R)) therapy. Future Oncol 4 457 469
13. StasiR
EvangelistaML
BuccisanoF
VendittiA
AmadoriS
2008 Gemtuzumab ozogamicin in the treatment of acute myeloid leukemia. Cancer Treat Rev 34 49 60
14. DadachovaE
CasadevallA
2008 Host and microbial cells as targets for armed antibodies in the treatment of infectious diseases. Curr Opin Investig Drugs 9 184 188
15. GalloRC
MontagnierL
2003 Retrospective: the discovery of HIV as the cause of AIDS. N Eng J Med 349 2283 2285
16. ChaudharyVK
MizukamiT
FuerstTR
FitzGeraldDJ
MossB
1988 Selective killing of HIV-infected cells by recombinant human CD4-Pseudomonas exotoxin hybrid protein. Nature 335 369 372
17. TillMA
GhetieV
GregoryT
PatzerEJ
PorterJP
1988 HIV-infected cells are killed by rCD4-ricin A chain. Science 242 1166 1168
18. PincusSH
WehrlyK
ChesebroB
1989 Treatment of HIV tissue culture infection with monoclonal antibody-ricin A chain conjugates. J Immunol 142 3070 3075
19. AulloP
AlcamiJ
PopoffMR
KlatzmannDR
MurphyJR
1992 A recombinant diphtheria toxin related human CD4 fusion protein specifically kills HIV infected cells which express gp120 but selects fusion toxin resistant cells which carry HIV. EMBO J 11 575 583
20. FinbergRW
WahlSM
AllenJB
SomanG
StromTB
1991 Selective elimination of HIV-1-infected cells with an interleukin-2 receptor-specific cytotoxin. Science 252 1703 1705
21. ZhangL
WatersC
NicholsJ
CrumpackerC
1992 Inhibition of HIV-1 RNA Production by the Diphtheria Toxin- Related IL-2 Fusion Proteins DAB(486)IL-2 and DAB(389)IL-2. J Acquir Immune Defic Syndr 5 1181 1187
22. RamiloO
BellKD
UhrJW
VitettaES
1993 Role of CD25+ and CD25- T-cells in acute HIV-infection invitro. J Immunol 150 5202 5208
23. McCoigC
Van DykeG
ChouCS
PickerLJ
RamiloO
1999 An anti-CD45RO immunotoxin eliminates T cells latently infected with HIV-1 in vitro. Proc Natl Acad Sci U S A 96 11482 11485
24. WolfP
Elsasser-BeileU
2009 Pseudomonas exotoxin A: From virulence factor to anti-cancer agent. Int J Med Microbiol 299 161 176
25. PastanI
HassanR
FitzGeraldDJ
KreitmanRJ
2006 Immunotoxin therapy of cancer. Nat Rev Cancer 6 559 565
26. BergerEA
ChaudharyVK
ClouseKA
JaraquemadaD
NicholasJA
1990 Recombinant CD4-Pseudomonas exotoxin hybrid protein displays HIV-specific cytotoxicity without affecting MHC class II-dependent functions. AIDS Res Hum Retroviruses 6 795 804
27. AshornP
MossB
BergerEA
1992 Activity of CD4-Pseudomonas exotoxin against cells expressing diverse forms of the HIV and SIV envelope glycoproteins. J Acquir Immune Defic Syndr 5 70 77
28. BeraTK
KennedyPE
BergerEA
BarbasCFI
PastanI
1998 Specific killing of HIV-infected lymphocytes by a recombinant immunotoxin directed against the HIV-1 envelope glycoprotein. Mol Med 4 384 391
29. BergerEA
ClouseKA
ChaudharyVK
ChakrabartiS
FitzGeraldDJ
1989 CD4-Pseudomonas exotoxin hybrid protein blocks the spread of human immunodeficiency virus infection in vitro and is active against cells expressing the envelope glycoproteins from diverse primate immunodeficiency retroviruses. Proc Natl Acad Sci U S A 86 9539 9543
30. AshornP
MossB
WeinsteinJN
ChaudharyVK
FitzGeraldDJ
1990 Elimination of infectious human immunodeficiency virus from human T-cell cultures by synergistic action of CD4-Pseudomonas exotoxin and reverse transcriptase inhibitors. Proc Natl Acad Sci U S A 87 8889 8893
31. AshornP
EnglundG
MartinMA
MossB
BergerEA
1991 Anti-HIV activity of CD4-Pseudomonas exotoxin on infected primary human lymphocytes and monocyte/macrophages. J Infect Dis 163 703 709
32. KennedyPE
MossB
BergerEA
1993 Primary HIV-1 isolates refractory to neutralization by soluble CD4 are potently inhibited by CD4-Pseudomonas exotoxin. Virology 192 375 379
33. VerhoefJ
GekkerG
EriceA
PetersonPK
BalfourHH
1992 Quantitative assay for testing susceptibility of HIV isolates to zidovudine and sCD4 (178)-PE40. Eur J Clin Microbiol Infect Dis 11 715 721
34. WintersMA
MeriganTC
1993 Continuous Presence of CD4-PE40 Is Required for Antiviral Activity Against Single-Passage HIV Isolates and Infected Peripheral Blood Mononuclear Cells. AIDS Res Hum Retroviruses 9 1091 1096
35. GorryPR
ChurchillM
CroweSM
CunninghamAL
GabuzdaD
2005 Pathogenesis of macrophage tropic HIV-1. Curr HIV Res 3 53 60
36. ColemanCM
WuL
2009 HIV interactions with monocytes and dendritic cells: viral latency and reservoirs. Retrovirology 6 51
37. DaveyRT
BoenningCM
HerpinBR
BattsDH
MetcalfJA
1994 Use of recombinant soluble CD4 Pseudomonas exotoxin, a novel immunotoxin, for treatment of persons infected with human immunodeficiency virus. J Infect Dis 170 1180 1188
38. RamachandranRV
KatzensteinDA
WoodR
BattsDH
MeriganTC
1994 Failure of short-term CD4-PE40 infusions to reduce virus load in human immunodeficiency virus-infected persons. J Infect Dis 170 1009 1013
39. BergerEA
MossB
PastanI
1998 Reconsidering targeted toxins to eliminate HIV infection: You gotta have HAART. Proc Natl Acad Sci U S A 95 11511 11513
40. KreitmanRJ
WilsonWH
BergeronK
RaggioM
Stetler-StevensonM
2001 Efficacy of the anti-CD22 recombinant immunotoxin BL-22 in chemotherapy-resistant hairy-cell leukemia. N Engl J Med 345 241 247
41. KreitmanRJ
Stetler-StevensonM
MarguliesI
NoelP
FitzGeraldDJP
2009 Phase II trial of recombinant immunotoxin RFB4(dsFv)-PE38 (BL22) in patients with hairy cell leukemia. J Clin Oncol 27 2983 2990
42. BarbasCF
HuD
DunlopN
SawyerL
CababaD
1994 In vitro evolution of a neutralizing human antibody to human immunodeficiency virus type 1 to enhance affinity and broaden strain cross-reactivity. Proc Natl Acad Sci U S A 91 3809 3813
43. KennedyPE
BeraTK
WangQC
GalloM
WagnerW
2006 Anti-HIV-1 immunotoxin 3B3(Fv)-PE38: enhanced potency against clinical isolates in human PBMCs and macrophages, and negligible hepatotoxicity in macaques. J Leukoc Biol 80 1175 1182
44. OndaM
NagataS
TsutsumiY
VincentJJ
WangQC
2001 Lowering the isoelectric point of the Fv portion of recombinant immunotoxins leads to decreased nonspecific animal toxicity without affecting antitumor activity. Cancer Res 61 5070 5077
45. GoldsteinH
Pettoello-MantovaniM
BeraTK
PastanIH
BergerEA
2000 Chimeric toxins targeted to the human immunodeficiency virus type 1 envelope glycoprotein augment the in vivo activity of combination antiretroviral therapy in thy/liv-scid-hu mice. J Infect Dis 181 921 926
46. UberlaK
StahlhennigC
BottigerD
MatzrensingK
KaupFJ
1995 Animal model for the therapy of acquired-immunodeficiency syndrom with reverse transcriptase inhibitors. Proc Natl Acad Sci U S A 92 8210 8214
47. IgarashiT
BrownCR
EndoY
Buckler-WhiteA
PlishkaR
2001 Macrophage are the principal reservoir and sustain high virus loads in rhesus macaques after the depletion of CD4(+) t cells by a highly pathogenic simian immunodeficiency virus/hiv type 1 chimera (shiv): implications for hiv-1 infections of humans. Proc Natl Acad Sci U S A 98 658 663
48. AmbroseZ
PalmerS
BoltzVF
KearneyM
LarsenK
2007 Suppression of viremia and evolution of human immunodeficiency virus type 1 drug resistance in a macaque model for antiretroviral therapy. J Virol 81 12145 12155
49. Van RompayKKA
JohnsonJA
BlackwoodEJ
SinghRP
LipscombJ
2007 Sequential emergence and clinical implications of viral mutants with K70E and K65R mutation in reverse transcriptase during prolonged tenofovir monotherapy in rhesus macaques with chronic RT-SHIV infection. Retrovirology 4 25
50. DinosoJB
RabiSA
BlanksonJN
GamaL
MankowskiJL
2009 A simian immunodeficiency virus-infected macaque model to study viral reservoirs that persist during highly active antiretroviral therapy. J Virol 83 9247 9257
51. DinosoJB
KimSY
WiegandAM
PalmerSE
GangeSJ
2009 Treatment intensification does not reduce residual HIV-1 viremia in patients on highly active antiretroviral therapy. Proc Natl Acad Sci U S A 106 9403 9408
52. JonesJ
McMahonD
WiegandA
KearneyM
PalmerS
2009 No decrease in residual viremia during raltegravir intensification in patients on standard ART. 16th Conference on Retroviruses and Opportunistic Infections; 8–11 February 2009; Montreal, Canada. CROI 2009. [Abstract 423b]
53. BuzonM
LlibreJ
DomingoP
ParedesR
PalmerS
2009 Transient increase in episomal viral cDNA following raltegravir intensification of a stable HAART Regimen. 16th Conference on Retroviruses and Opportunistic Infections; 8-11 February 2009; Montreal, Canada. CROI 2009. [Abstract 423a]
54. BaileyJR
SedaghatAR
KiefferT
BrennanT
LeePK
2006 Residual human immunodeficiency virus type 1 viremia in some patients on antiretroviral therapy is dominated by a small number of invariant clones rarely found in circulating CD4(+) T cells. J Virol 80 6441 6457
55. BrennanTP
WoodsJO
SedaghatAR
SilicianoJD
SilicianoRF
2009 Analysis of human immunodeficiency virus type 1 viremia and provirus in resting CD4(+) T cells reveals a novel source of residual viremia in patients on antiretroviral therapy. J Virol 83 8470 8481
56. BrooksDG
HamerDH
ArlenPA
GaoLY
BristolG
2003 Molecular characterization, reactivation, and depletion of latent HIV. Immunity 19 413 423
57. MarsdenMD
XuJ
HamerD
ZackJA
2008 Activating stimuli enhance immunotoxin-mediated killing of HIV-infected macrophages. AIDS Res Hum Retroviruses 24 1399 1404
58. JohanssonS
GoldenbergDM
GriffithsGL
WahrenB
HinkulaJ
2006 Elimination of HIV-1 infection by treatment with a doxorubicin-conjugated anti-envelope antibody. AIDS 20 1911 1915
59. DadachovaE
PatelMC
ToussiS
ApostolidisC
MorgensternA
2006 Targeted killing of virally infected cells by radiolabeled antibodies to viral proteins. PLoS Med 3 e427 doi:10.1371/journal.pmed.0030427
60. OndaM
BeersR
XiangL
NagataS
WangQC
2008 An immunotoxin with greatly reduced immunogenicity by identification and removal of B cell epitopes. Proc Natl Acad Sci U S A 105 11311 11316
61. McHughL
HuS
LeeBK
SantoraK
KennedyPE
2002 Increased affinity and stability of an anti-HIV-1 envelope immunotoxin by structure-based mutagenesis. J Biol Chem 277 34383 34390
62. PincusSH
FangH
WilkinsonRA
MarcotteTK
RobinsonJE
2003 In vivo efficacy of anti-glycoprotein 41, but not anti- glycoprotein 120, immunotoxins in a mouse model of hiv infection. J Immunol 170 2236 2241
63. RootMJ
HamerDH
2003 Targeting therapeutics to an exposed and conserved binding element of the HIV-1 fusion protein. Proc Natl Acad Sci U S A 100 5016 5021
64. MontefioriD
SattentauQ
FloresJ
EsparzaJ
MascolaJ
2007 Antibody-based HIV-1 vaccines: recent developments and future directions. PLoS Med 4 e348 doi:10.1371/journal.pmed.0040348
65. WalkerLM
PhogatSK
Chan-HuiPY
WagnerD
PhungP
2009 Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target. Science 326 285 289
66. BrenchleyJM
DouekDC
2008 HIV infection and the gastrointestinal immune system. Mucosal Immunol 1 23 30
67. ChunTW
NickleDC
JustementJS
MeyersJH
RobyG
2008 Persistence of HIV in gut-associated lymphoid tissue despite long-term antiretroviral therapy. J Infect Dis 197 714 720
68. LundgrenJD
BabikerA
El-SadrW
EmeryS
GrundB
2008 Inferior clinical outcome of the CD4(+) cell count guided antiretroviral treatment interruption strategy in the SMART study: Role of CD4(+) cell counts and HIV RNA levels during follow-up. J Infect Dis 197 1145 1155
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