Microbial Virulence as an Emergent Property: Consequences and Opportunities

1. DaszakPBergerLCunninghamAAHyattADGreenDE 1999 Emerging infectious diseases and amphibian population declines. Emerg Infect Dis 5 735 748

2. PoundsJABustamanteMRColomaLAConsuegraJAFogdenMP 2006 Widespread amphibian extinctions from epidemic disease driven by global warming. Nature 439 161 167

3. BlehertDSHicksACBehrMMeteyerCUBerlowski-ZierBM 2009 Bat white-nose syndrome: an emerging fungal pathogen? Science 323 227

4. QuinnRW 1989 Comprehensive review of morbidity and mortality trends for rheumatic fever, streptococcal disease, and scarlet fever: the decline of rheumatic fever. Rev Infect Dis 11 928 953

5. TognottiE 2009 The rise and fall of syphilis in Renaissance Europe. J Med Humanit 30 99 113

6. BeesonPB 1980 Some diseases that have disappeared. Am J Med 68 806 811

7. FangFCCasadevallA 2011 Reductionistic and holistic science. Infect Immun 79 1401 1414

8. BironCACasadevallA 2010 On immunologists and microbiologists: ground zero in the battle for interdisciplinary knowledge. MBio 1 e00280 10

9. CasadevallAPirofskiL 2001 Host-pathogen interactions: the attributes of virulence. J Infect Dis 184 337 344

10. CasadevallAPirofskiL 1999 Host-pathogen interactions: redefining the basic concepts of virulence and pathogenicity. Infect Immun 67 3703 3713

11. BhallaUSIyengarR 1999 Emergent properties of networks of biological signaling pathways. Science 283 381 387

12. DubnauDLosickR 2006 Bistability in bacteria. Mol Microbiol 61 564 572

13. VeeningJWSmitsWKKuipersOP 2008 Bistability, epigenetics, and bet-hedging in bacteria. Annu Rev Microbiol 62 193 210

14. PosfaiGPlunkettGIIIFeherTFrischDKeilGM 2006 Emergent properties of reduced-genome Escherichia coli. Science 312 1044 1046

15. Van RegenmortelMH 2004 Reductionism and complexity in molecular biology. Scientists now have the tools to unravel biological and overcome the limitations of reductionism. EMBO Rep 5 1016 1020

16. WelshRMCheJWBrehmMASelinLK 2010 Heterologous immunity between viruses. Immunol Rev 235 244 266

17. DethlefsenLMcFall-NgaiMRelmanDA 2007 An ecological and evolutionary perspective on human-microbe mutualism and disease. Nature 449 811 818

18. CorningPA 2002 The re-emergence of ‘emergence’: a venerable concept in search for a theory. Complexity 7 18 30

19. GrantPRGrantBR 2002 Unpredictable evolution in a 30-year study of Darwin's finches. Science 296 707 711

20. AblowitzR 1939 The theory of emergence. Phil Sci 6 1 16

21. LofgrenEFeffermanNHNaumovYNGorskiJNaumovaEN 2007 Influenza seasonality: underlying causes and modeling theories. J Virol 81 5429 5436

22. RobertVACasadevallA 2009 Vertebrate endothermy restricts most fungi as potential pathogens. J Infect Dis 200 1623 1626

23. HoffmasterARRavelJRaskoDAChapmanGDChuteMD 2004 Identification of anthrax toxin genes in a Bacillus cereus associated with an illness resembling inhalation anthrax. Proc Natl Acad Sci U S A 101 8449 8454

24. TaylorLHLathamSMWoolhouseME 2001 Risk factors for human disease emergence. Philos Trans R Soc Lond B Biol Sci 356 983 989

25. WoolhouseMEHaydonDTAntiaR 2005 Emerging pathogens: the epidemiology and evolution of species jumps. Trends Ecol Evol 20 238 244

26. Garcia-SolacheMACasadevallA 2010 Global warming will bring new fungal diseases for mammals. MBio 1 e00061 10

27. BergmanACasadevallA 2010 Mammalian endothermy optimally restricts fungi and metabolic costs. MBio 1 00212 10

28. DayTProulxSR 2004 A general theory for the evolutionary dynamics of virulence. Am Nat 163 E40 E63

29. BootsMBestAMillerMRWhiteA 2009 The role of ecological feedbacks in the evolution of host defence: what does theory tell us? Philos Trans R Soc Lond B Biol Sci 364 27 36

30. NowakMASigmundK 2004 Evolutionary dynamics of biological games. Science 303 793 799

31. HashimotoK 2006 Unpredictability induced by unfocused games in evolutionary game dynamics. J Theor Biol 241 669 675

32. CarvalDFerriereR 2010 A unified model for the coevolution of resistance, tolerance, and virulence. Evolution 64 2988 3009

33. BootsMMealorM 2007 Local interactions select for lower pathogen infectivity. Science 315 1284 1286

34. BucklingA 2007 Epidemiology. Keep it local. Science 315 1227 1228

35. CleavelandSHaydonDTTaylorL 2007 Overviews of pathogen emergence: which pathogens emerge, when and why? Curr Top Microbiol Immunol 315 85 111

36. 1992 Emerging infections: microbial threats to the United States. Washington (D.C.) Institute of Medicine

37. Barre-SinoussiFChermannJCReyFNugeyreMTChamaretS 1983 Isolation of a T-lymphotropic retrovirus from a patient at risk for acquired immune deficiency syndrome (AIDS). Science 220 868 871

38. HsiungGD 1987 Perspectives on retroviruses and the etiologic agent of AIDS. Yale J Biol Med 60 505 514

39. PongeJF 2005 Emergent properties from organisms to ecosystems: towards a realistic approach. Biol Rev Camb Philos Soc 80 403 411

40. BaylisCA 1929 The philosophic functions of emergence. Philos Rev 38 372 384

41. HenpelCGOppenheimP 2011 Studies in the logic of explanation. Phil Sci 15 135 175

42. MazzocchiF 2008 Complexity in biology. Exceeding the limits of reductionism and determinism using complexity theory. EMBO Rep 9 10 14

43. ParrishJKViscidoSVGrumbaumD 2011 Self organized fish schools: an example of emergent properties. Biol Bull 202 296 305