Current options for anti-aggregation treatment for the prevention of atherosclerotic complications in diabetic patients
Authors:
J. Špác
Published in the journal:
Kardiol Rev Int Med 2006, 8(3): 105-111
Category:
Editorial
Summary
Type II diabetes mellitus (DM) has become one of the major health issues in developed countries. Anti-aggregation treatment forms integral part of pharmacological measures to improve the prognosis of diabetic patients and to postpone the manifestation of macrovascular complications in the first place. Platelet activity has a number of specific pathophysiological features in diabetic patients, and treatment affecting the formation of a white platelet thrombus is of utmost importance for these patients. Current knowledge of the effect of anti-aggregation treatment draws solely on analysis of subgroups of diabetic patients within large clinical studies. The principal problem of current anti-aggregation treatment of diabetic patients is its low efficiency providing protection against acute vascular events to a minor percentage of patients only.
Keywords:
diabetes mellitus – thrombogenesis – ACE inhibitors – beta-blockers – statins – anti-aggregation treatment – thienopyridines
Zdroje
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Štítky
Paediatric cardiology Internal medicine Cardiac surgery CardiologyČlánok vyšiel v časopise
Cardiology Review
2006 Číslo 3
Najčítanejšie v tomto čísle
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