Precancerous Conditions in the ENT Area

Česká verzia

Authors: B. Gál ¹ ; L. Mrzena ²; P. Hort ³
Authors place of work: Klinika otorinolaryngologie a chirurgie hlavy a krku LF MU a FN u sv. Anny v Brně ¹; Klinika otorinolaryngologie a chirurgie hlavy a krku 1. LF UK a FN v Motole ²; ORL oddělení, Vojenská nemocnice Brno ³
Published in the journal: Klin Onkol 2013; 26(Supplementum): 13-16

Summary

An important part of tumor prevention is early detection, diagnosis, treatment and screening of precancerous conditions. Correct detection and screening of premalignant lesions leads to early diagnosis of a malignant process which provides a better chance to completely cure the patient and also predicts better quality of life. Precancerous conditions look like whitish, red or mixed mucose lesions (leukoplakia, erytroplakia, erytroleukoplakia) which are visible during clinical examination. Nevertheless, these mucose changes are not absolutely conclusive. Therefore, histological testing is necessary for diagnosis and determination of biological potencial of precancerous lesions. Precancerous lesions as a term of histological terminology means dysplasia. The risk of progression of dysplasia into a carcinoma depends on a grade of dysplasia. The conservative or surgical treatment is chosen according to localisation and grade of dysplasia.

Key words:
precancerous condition – premalignant lesion – ENT – dysplasia – leukoplakia – erytroplakia – carcinoma in situ

The authors declare they have no potential conflicts of interest concerning drugs, products, or services used in the study.

The Editorial Board declares that the manuscript met the ICMJE “uniform requirements” for biomedical papers.

Submitted:
15. 9. 2013

Accepted:
17. 10. 2013

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