Application of inhaled drugs from the pharmacist’s point of view
Authors:
Lucia Masaryková; Petra Polaščíková
Published in the journal:
Čes. slov. Farm., 2020; 69, 172-184
Category:
Original Articles
Summary
The basis of asthma and chronic obstructive pulmonary disease (COPD) treatment is inhalation therapy, which brings several benefits and its success is based on the correct inhalation technique.
Aim: The primary aim of the research was to find out what percentage of patients could apply their medicines properly, what inhalation systems were preferred in the treatment of these respiratory diseases, what most common mistakes in the inhalation technique patients made when using inhalers as well as what was patients’ approach to the possibility of being educated by a community pharmacist.
Methods: Essential data to accomplish the goal were obtained by a questionnaire survey in which 102 respondents (patients) participated. The anonymous questionnaire consisted of 18 questions focusing on the inhalation systems that patients use and particular steps that need to be taken when inhaling the medicine.
Results: 83.33 % of patients with bronchial asthma and 9.8 % of patients with chronic obstructive lung disease (COPD) participated in the study. “Inhaler” was the most prescribed out of all the other kinds of inhalators, used by 54.9 % of respondents. It turned out that up to 63 % of the respondents using MDIs or DPIs had encounetered some kind of error when inhaling their drugs. The most common mistake with both types of inhalation systems was not holding their breath for sufficient time (5 to 10 seconds) after inhaling from the inhaler. Dry–powder inhalers (DPIs) proved to be used more erroneously compared to aerosol dispensers (MDIs).
Conclusion: The obtained results showed that errors in the inhalation technique seem yet to be a hot issue for more than half of patients with respiratory diseases. Pharmacists have a great potential to improve the situation by giving pieces of advice and instructions regarding the proper application of medicines to help patients to enhance the performance of inhalation and thus increase the treatment efficiency.
Keywords:
Asthma – adherence
Zdroje
1. Global Initiative for Asthma. Global Strategy for Asthma Management and Prevention [online] 2020 [cit. 2020-09-14]. Dostupné na: https://ginasthma.org/wp-content/uploads/2020/04/GINA-2020-full-report_-final-_wms.pdf
2. Kašák V. Bronchiální astma. Medicína pro praxi [online] 2010; 7(8 a 9), 319–321 [cit. 2020-06-19]. Dostupné na: https://www.medicinapropraxi.cz
3. Xie M., et al. Trends in prevalence and incidence of chronic respiratory diseases from 1990 to 2017. Respir. Res. 2020; 21 (49). [cit. 2020-08-12] Dostupné na: https://respiratory-research.biomedcentral.com/articles/10.1186/s12931-020-1291-8
4. Národné centrum zdravotníckych informácií. Zdravotnícka ročenka SR 2018 [online] 2019 [cit. 2020-06-21]. Dostupné na: http://www.nczisk.sk/Documents/rocenky/2018/Zdravotnicka_rocenka_Slovenskej_republiky_2018.pdf
5. ZDRAVOTNICTVÍ ČR: Stručný přehled činností oboru pneumologie a ftizeologie za období 2007–2018. Ústav zdravotnických informací a statistiky ČR 2019 [cit. 2020-09-14]. Dostupné na: www.uzis.cz
6. Rang H. P., et al. Respiratory system. Rang & Dale’s Pharmacology. 7th Edition. Edinburgh: Churchill Livingstone 2012.
7. Teřl M., et al. Doporučený postup diagnostiky a léčby brochiálního astmatu [online]. Semily: Geum 2015 [cit. 2020-06-20]. Dostupné na: http://www.csaki.cz
8. Global Initiative for Chronic Obstructive Lung Disease (GOLD). Pocket Guide to COPD Diagnosis, Management and Prevention [online] 2020 [cit. 2020-09-14]. Dostupné na: https://goldcopd.org
9. Gray A. H., et al. Clinical Pharmacy Pocket Companion [online]. London: Pharmaceutical Press 2015 [cit. 2020-06-22], 2. vydanie. Dostupné na: http://ebookcentral.proquest.com
10. Drugdová M., et al. Chronická obštrukčná choroba pľúc. Národné smernice pre prevenciu a terapiu [online] 2011 [cit. 2020-06-21]. Dostupné na: http://www.copdplatform.com
11. Rozborilová E. Chronická obštrukčná choroba pľúc. Via practica [online] 2005; 2(2), 89–93 [cit. 2020-06-22]. Dostupné na: http://www.solen.sk
12. Vondra V., Vondrová I. Diferenciální diagnóza a terapie chronické obstruční plicní nemoci a astmatu. Interní Med. 2012; 14(10), 350–356.
13. Pauk N. Fenotyp překryvu CHOPN s astmatem (ACOS). Farmakoterapie 2014; 1 [cit. 2020-08-12]. Dostupné na: www.farmakoterapie.cz
14. Kašáková E., Kašák V. Inhalační systémy na českém trhu pro léčbu pacientů s chronickou obstrukcí průdušek. Praktické lékárenství [online] 2015; 11(1), 16–18 [cit. 2020-06-18]. Dostupné na: http://www.praktickelekarenstvi.cz
15. Rau J. L. The Inhalation of Drugs: Advantages and Problems. Respiratory Care [online] 2005; 50(3), 367–382 [cit. 2020-06-21]. Dostupné na: http://rc.rcjournal.com
16. Takaku Y., et al. How many instructions are required to correct inhalation errors in patients with asthma and chronic obstructive pulmonary disease? Respiratory Medicine [online] 2017; 123, 110–115 [cit. 2020-06-23]. Dostupné na: http://www.sciencedirect.com
17. Wu A. A Pharmacist’s Role in the Management of Chronic Obstructive Pulmonary Disease. US Pharmacist [online] 2016; 41(7), 42–46 [cit. 2020-06-22]. Dostupné na: https://www.uspharmacist.com
18. Kašák V. Nové inhalační systémy užívané v léčbě chronických nemocí dýchacího ústrojí s obstrukcí dýchacích cest. Remedia [online] 2007; 17(1), 26–38 [cit. 2020-06-26]. Dostupné na: http://www.remedia.cz
19. Pocket guide for asthma management and prevention (for adults and children older than 5 years. Global Initiative for Asthma [online] 2018 [cit. 2020-06-23]. Dostupné na: https://ginasthma.org
20. Terrie Y. C. Managing asthma: The pharmacist’s role. Pharmacy Times [online] 2014; 80(4), [cit. 2020-06-28]. Dostupné na: http://www.pharmacytimes.com
21. Hesso I., Gebara S. N., Kayyali R. Impact of community pharmacists in COPD management: Inhalation technique and medication adherence. Respiratory Medicine [online] 2016; 118, 22–30 [cit. 2020-06-17]. Dostupné na: http://www.sciencedirect.com
22. Snopková M., et al. Lekárenská prax. Bratislava: Univerzita Komenského v Bratislave 2017.
23. Price D. B., et al. Inhaler errors in the CRITIKAL study: Type, frequency, and association with asthma outcomes. The Journal of Allergy and Clinical Immunology: In Practice [online] 2017; 5(4), 1071–1081 [cit. 2020-5-21]. Dostupné na: https://search.proquest.com
24. Teřl M. Léčba astmatu – chyby a omyly každodenní praxe. Medicína pro praxi [online] 2013; 10(3), 97–103 [cit. 2020-5-25]. Dostupné na: https://www.solen.cz
25. Vondra V. Optimální inhalace antiastmatik a chyby při inhalování. Praktické lékárenství [online] 2009; 5(4), 179–181 [cit. 2020-5-26]. Dostupné na: https://www.praktickelekarenstvi.cz
26. Castel-Branco M. M., Fontes A., Figueiredo I. V. Identification of inhaler technique errors with a routine procedure in Portuguese community pharmacy. Pharmacy Practice [online] 2017; 15(4), Article number 1072 [cit. 2020-5-26]. Dostupné na: https://www.scopus.com
27. Correct inhalation. Deutche Atemwegsliga e.V. [cit. 2020-09-14]. Dostupné na: https://www.atemwegsliga.de/en/index.html
Štítky
Pharmacy Clinical pharmacologyČlánok vyšiel v časopise
Czech and Slovak Pharmacy
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