Therapy of chronic hepatitis C with simeprevir

Česká verzia

Authors: P. Urbánek
Authors place of work: Interní klinika 1. LF UK a ÚVN Praha
Published in the journal: Gastroent Hepatol 2015; 69(2): 103-108
Category: Hepatology: Review article
doi: https://doi.org/10.14735/amgh2015103

Summary

This review presents all essential information on simeprevir and its use in the therapy of chronic hepatitis C. The review is focused on the curent role of simeprevir in IFN‑based regimens as well as its role in IFN‑free regimens.

Key words:
viral hepatitis C – simeprevir – pegylated interferon

The author declares he has no potential conflicts of interest concerning drugs, products, or services used in the study.

The Editorial Board declares that the manuscript met the ICMJE „uniform requirements“ for biomedical papers.

Zdroje

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2. Manns M, Marcellin P, Poordad F et al. Simeprevir with pegylated interferon alfa 2a or 2b plus ribavirin in treatment‑ naive patients with chronic hepatitis C virus genotype 1 infection (QUEST‑2): a randomised, double‑blind, placebo‑ controlled phase 3 trial. Lancet 2014; 384(9941): 414– 426. doi: 10.1016/ S0140‑ 6736(14)60538‑ 9.

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