Talc - Standard Medicament in the Treatment of Malignant Pleural Effusion

České info

TALEK - STANDARDNÍ LÉK V TERAPII MALIGNÍCHPLEURÁLNÍCH VÝPOTKŮ

Talek je v současné době ve světě nejpoužívanějším prostředkem pro chemickou pleurodézu při pleurálním výpotkua pneumotoraxu. Jeho obliba vzrostla zejména v posledních letech díky nízké ceně, vysoké účinnosti v porovnánís ostatními používanými látkami (tetracykliny, Corynebacterium parvum, bleomycin) a nízkému výskytu kompli-kací. Je zmíněna historie přípravku Corynebacterium parvum, jehož výroba v očekávání brzkého příklonu našichklinických lékařů k talku končí.

Klíčová slova:
maligní výpotek, pneumothorax, pleurodéza, talek, Corynebacterium parvum, tetracyklin, bleo-mycin.

Authors: M. Bednář; P. Bezdíček ¹
Authors‘ workplace: Ústav lékařské mikrobiologie 3. LF UK a FNKV, Praha, 1 Division of Pulmonary and Critical Care Medicine, The New York Hospital - Cornell University Medical College, New York, USA
Published in: Čas. Lék. čes. 1999; : 82-84
Category:

Overview

Currently, talc is the most effective and widely-used agent for chemical pleurodesis in the treatment of bothmalignant pleural effusion and pneumothorax. Its popularity has been growing due to the low incidence of sideeffects, low cost and higher success rate in comparison with other agents (tetracyclines, bleomycin, Corynebacteriumparvum). The guidelines for talc pleurodesis are summarized and the history of the Corynebacterium parvum as anagent for chemical pleurodesis is mentioned. Its production in the Czech Republic has been halted due to the increasedinterest in the talc as a chemical sclerosant.

Key words:
malignant effusion, pneumothorax, pleurodesis, talc, Corynebacterium parvum, tetracyclin, bleomy-cin.

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Addictology Allergology and clinical immunology Angiology Audiology Clinical biochemistry Dermatology & STDs Paediatric gastroenterology Paediatric surgery Paediatric cardiology Paediatric neurology Paediatric ENT Paediatric psychiatry Paediatric rheumatology Diabetology Pharmacy Vascular surgery Pain management Dental Hygienist

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