Significance of Determination of the Hydrogen Peroxide in Expired Air for the Diagnostics of OxidativeLung Impairment
Význam stanovovania peroxidu vodíkavo vydychovanom vzduchu pre hodnotenieoxidačného poškodenia pľúc
Klasické vyšetrovacie metódy respiračného traktu sa rozšírili o biochemickú analýzu vydychovaného vzduchu.Jednou z látok často stanovovaných pri hľadaní markerov pľúcnych chorôb je peroxid vodíka. Táto práca zhŕňaliterárne údaje o postavení peroxidu vodíka v metabolizme kyslíkových radikálov, metodických možnostiach detekciekoncentrácie H2O2 vo vydychovanom vzduchu a hodnotách jeho produkcie pri pľúcnych chorobách.
Klíčová slova:
oxidačný stres, respiračná diagnostika, reaktívne formy kyslíka, peroxid vodíka.
Authors:
P. Hitka
Authors‘ workplace:
Ústav patologické fyziologie 2. LF UK, Praha
Published in:
Čas. Lék. čes. 2003; : 202-206
Category:
Overview
Classical methods of respiratory diagnosis were extended with methods allowing determination of the metabolicproducts from lung tissue – the biochemical analysis of expired air. Hydrogen peroxide is one of the substances usedas markers of pathological processes in the respiratory system. This review describes position of hydrogen peroxidein the metabolic pathway of reactive oxygen species, methods of hydrogen peroxide measurement in expired air andchanges in hydrogen peroxide production in lung diseases.
Key words:
oxidative stress, respiratory diseases diagnostics, reactive oxygen species, hydrogen peroxide.
Labels
Addictology Allergology and clinical immunology Angiology Audiology Clinical biochemistry Dermatology & STDs Paediatric gastroenterology Paediatric surgery Paediatric cardiology Paediatric neurology Paediatric ENT Paediatric psychiatry Paediatric rheumatology Diabetology Pharmacy Vascular surgery Pain management Dental HygienistArticle was published in
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