Intracranial Hypertension in Acute Liver Failure and Microdialysis

Česká verzia

Authors: J. Pražák ¹; E. Lásziková ²; O. Ryska ³; M. Ryska ⁴
Authors place of work: Klinika anesteziologie, resuscitace a intenzivní péče 2. LF UK ¹; Anesteziologicko-resuscitační oddělení ÚVN Praha ²; Chirurgická klinika 1. LF UK Praha, Nemocnice na Bulovce, Praha ³; Chirurgická klinika 2. LF UK a ÚVN Praha ⁴
Published in the journal: Rozhl. Chir., 2010, roč. 89, č. 10, s. 642-646.
Category: Monothematic special - Original

Summary

Acute liver failure is a severe condition with a very unfavourable prognosis. One of the common complications and limiting factors for the outcome is the development of the intracranial hypertension. The etiology and the pathogenetic pathways leading to the development of this fatal complication of acute liver failure is still not completely understood. The aim of this review is to inform about the actual knowledge of pathogenesis of the intracranial hypertenson in acute liver failure. Finally, a new method of tissue metabolism monitoring – microdialysis – is shortly discussed as a perspective method in monitoring and research on acute liver failure.

Key words:
intracranial hypertension – acute liver failure – microdialysis

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