A giant gastrointestinal stromal tumour – a case report
Authors:
L. Tulinský 1
; J. Dostalík 1; J. Dvořáčková 2; R. Tomanová 2
Authors place of work:
Chirurgická klinika LF OU a FN v Ostravě, přednosta: Doc. MUDr. J. Dostalík, CSc.
1; Ústav patologie FN Ostrava, přednosta: MUDr. J. Dvořáčková, Ph. D.
2
Published in the journal:
Rozhl. Chir., 2012, roč. 91, č. 9, s. 486-489.
Category:
Case Report
Summary
Gastrointestinal stromal tumours represent a group of non-epithelial gastrointestinal tumours that have both benign and malignant character. Most frequently, they occur in the stomach and the intestine; however, as regards their overall incidence, they are rather infrequent tumour lesions. The present case report describes a rare bulky extragastrointestinal stromal tumour originating from the mesenterium in a young patient. Its anatomical and histological picture, diagnosis and treatment are described. Our work points to the necessity for physicians to also bear in mind the less likely options and highlights the role of surgery in the treatment of such voluminous findings.
Key words:
stromal tumour – R0 resection – immunohistochemistry
Zdroje
1. Miettinen M, Sarlomo-Rikala M, Lasota J. Gastrointestinal stromal tumors: recent advances in understanding of their biology. Hum Pathol 1999;30(10):1213–1220.
2. Miettinen M, Sobin LH, Lasota J. Gastrointestinal stromal tumors of the stomach: a clinicopathologic, immunohistochemical, and molecular genetic study of 1765 cases with long-term follow-up. Am J Surg Pathol 2005;29(1):52–68.
3. Miettinen M, Lasota J. Gastrointestinal stromal tumors: pathology and prognosis at different sites. Semin Diagn Pathol 2006;23(2):70–83.
4. Corless ChL, Heinrich MC. Molecular Pathobiology of Gastrointestinal Stromal Sarcomas. Annu Rev Pathol Mech Dis 2008;3:557–586. Downloaded from arjournals.annualreviews. org.
5. Mazur MT, Clark HB. Gastric stromal tumors. Reappraisal of histogenesis. Am J Surg Pathol 1983;7(6):507–519.
6. Sircar K, Hewlett BR, Huizinga JD et al. Interstitial cells of Cajal as precursors of gastrointestinal stromal tumors. Am J Surg Pathol 1999;23(4):377–389.
7. Heinrich MC, Griffith DJ, Druker BJ, Wait CL, Ott KA, Zigler AJ. 2000. Inhibition of c-kit receptor tyrosine kinase activity by STI 571, a selective tyrosine kinase inhibitor. Blood 96:925–32.
8. DeMatteo RP, Lewis JJ, Leung D, Mudan SS, Woodruff JM, Brennan MF. Two hundred Gastrointestinal Stromal Tumors recurrence patterns and prognostic factors for survival. Ann Surg 2000;231(1):51.
9. Gold JS, Gonen M, Gutierrez A et al. Development and validation of a prognostic nomogram for recurrence-free survival after complete surgical resection of localised primary gastrointestinal stromal tumour: a retrospective analysis. Lancet Oncol 2009; 10(11):1045–1052.
Štítky
Surgery Orthopaedics Trauma surgeryČlánok vyšiel v časopise
Perspectives in Surgery
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Najčítanejšie v tomto čísle
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