Thromboprophylaxis at Caesarean section

Česká verzia

Authors: Jan Bláha ¹; Kateřina Bláhová ²; Ivana Kolníková ¹; MUDr. Pavlína Nosková, Ph.D. ¹
Authors place of work: Klinika anesteziologie, resuscitace a intenzivní medicíny 1. LF UK a VFN v Praze ¹; Gynekologicko-porodnická klinika 1. LF UK a VFN v Praze ²
Published in the journal: Prakt Gyn 2012; 16(2-4): 81-88
Category: Gynecology and Obstetrics: Review Article

Summary

Thromboembolism in developed countries belongs to the most frequent causes of maternal mortality and morbidity. A caesarean section is regarded as one of the important risk factors; therefore pharmacologic thromboprophylaxis with low-molecular-weight heparins (LMWH) is now a standard part of perioperative care for the woman in operative labor. On the basis of current evidence, however, the universal effectiveness of this prophylaxis in cesarean delivery is at least a matter of controversy. Prevention of TEN should not be generalized, but strictly on the basis of individualized risk stratification for each patient, while in patients with low risk of TEN an application of LMWH is no longer generally recommended. Therefore the aim of this article is to review the issue of thromboembolism in pregnant women with a specific focus on the caesarean section.

Key words:
thromboembolism – thromboprophylaxis – caesarean sectio – pregnancy – low molecular weight heparins – LMWH

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