Sugammadex from the perspective of evidence-based medicine

Česká verzia

Authors: Adamus Milan ¹; Herold Ivan ²
Authors place of work: Klinika anesteziologie, resuscitace a intenzivní medicíny Fakultní nemocnice a Lékařská fakulta Univerzity Palackého v Olomouci ¹; Anesteziologicko-resuscitační oddělení, Oblastní nemocnice Mladá Boleslav, a. s. ²
Published in the journal: Anest. intenziv. Med., 23, 2012, č. 5, s. 237-241
Category: Anesteziologie - Přehledový článek

Summary

Sugammadex is a novel drug for reversal of rocuronium or vecuronium-induced neuromuscular blockade. Compared to neostigmine, its mechanism of action (encapsulation) is not influenced by cholinesterase activity. In this article, the authors summarize the current indications of sugammadex, its advantages over neostigmine and its value in specific situations during anaesthesia.

Keywords:
neuromuscular blockade – rocuronium – encapsulation – sugammadex

Zdroje

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