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Epistatic Relationships in the BRCA1-BRCA2 Pathway

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Vyšlo v časopise: Epistatic Relationships in the BRCA1-BRCA2 Pathway. PLoS Genet 7(7): e32767. doi:10.1371/journal.pgen.1002183
Kategorie: Perspective
prolekare.web.journal.doi_sk: https://doi.org/10.1371/journal.pgen.1002183

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Zdroje

1. LudwigTChapmanDLPapaioannouVEEfstratiadisA 1997 Targeted mutations of breast cancer susceptibility gene homologs in mice: lethal phenotypes of Brca1, Brca2, Brca1/Brca2, Brca1/p53, and Brca2/p53 nullizygous embryos. Genes Dev 11 1226 1241

2. BouwmanPAlyAEscandellJMPieterseMBartkovaJ 2010 53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers. Nat Struct Mol Biol 17 688 695

3. BuntingSFCallenEWongNChenHTPolatoF 2010 53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks. Cell 141 243 254

4. QingYYamazoeMHirotaKDejsuphongDSakaiW 2011 The epistatic relationship between BRCA2 and the other RAD51 mediators in homologous recombination. PLoS Genet 7 e1002148 doi:10.1371/journal.pgen.1002148

5. SonodaESasakiMSBuersteddeJMBezzubovaOShinoharaA 1998 Rad51-deficient vertebrate cells accumulate chromosomal breaks prior to cell death. Embo J 17 598 608

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Článok vyšiel v časopise

PLOS Genetics

2011 Číslo 7

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Autori: MUDr. Tomáš Ürge, PhD.

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