Animal Models Are Valid to Uncover Disease Mechanisms

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Vyšlo v časopise: Animal Models Are Valid to Uncover Disease Mechanisms. PLoS Genet 12(5): e32767. doi:10.1371/journal.pgen.1006013
Kategorie: Perspective
prolekare.web.journal.doi_sk: https://doi.org/10.1371/journal.pgen.1006013

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1. Jaramillo TC, Liu S, Pettersen A, Birnbaum SG, Powell CM (2014) Autism-related neuroligin-3 mutation alters social behavior and spatial learning. Autism Res 7: 264–272. doi: 10.1002/aur.1362 24619977

2. Keane TM, Goodstadt L, Danecek P, White MA, Wong K, et al. (2011) Mouse genomic variation and its effect on phenotypes and gene regulation. Nature 477: 289–294. doi: 10.1038/nature10413 21921910

3. Arbogast T, Ouagazzal A, Chevalier C, Kopanitsa M, Afinowi N, et al. (2016) Reciprocal effects on neurocognitive and metabolic phenotypes in mouse models of 16p11.2 deletion and duplicaton syndroms. PLoS Genet 12(2): e1005709. doi: 10.1371/journal.pgen.1005709 26872257

4. Walsh KM, Bracken MB (2011) Copy number variation in the dosage-sensitive 16p11.2 interval accounts for only a small proportion of autism incidence: a systematic review and meta-analysis. Genet Med 13: 377–384. doi: 10.1097/GIM.0b013e3182076c0c 21289514

5. Horev G, Ellegood J, Lerch JP, Son YE, Muthuswamy L, et al. (2011) Dosage-dependent phenotypes in models of 16p11.2 lesions found in autism. Proc Natl Acad Sci U S A 108: 17076–17081. doi: 10.1073/pnas.1114042108 21969575

6. Portmann T, Yang M, Mao R, Panagiotakos G, Ellegood J, et al. (2014) Behavioral abnormalities and circuit defects in the basal ganglia of a mouse model of 16p11.2 deletion syndrome. Cell Rep 7: 1077–1092. doi: 10.1016/j.celrep.2014.03.036 24794428

7. Chavez A, Scheiman J, Vora S, Pruitt BW, Tuttle M, et al. (2015) Highly efficient Cas9-mediated transcriptional programming. Nat Methods 12: 326–328. doi: 10.1038/nmeth.3312 25730490

8. Kraft K, Geuer S, Will AJ, Chan WL, Paliou C, et al. (2015) Deletions, Inversions, Duplications: Engineering of Structural Variants using CRISPR/Cas in Mice. Cell Rep.

9. Yang H, Wang H, Shivalila CS, Cheng AW, Shi L, et al. (2013) One-step generation of mice carrying reporter and conditional alleles by CRISPR/Cas-mediated genome engineering. Cell 154: 1370–1379. doi: 10.1016/j.cell.2013.08.022 23992847

10. Lin GN, Corominas R, Lemmens I, Yang X, Tavernier J, et al. (2015) Spatiotemporal 16p11.2 protein network implicates cortical late mid-fetal brain development and KCTD13-Cul3-RhoA pathway in psychiatric diseases. Neuron 85: 742–754. doi: 10.1016/j.neuron.2015.01.010 25695269

11. Lerner TN, Shilyansky C, Davidson TJ, Evans KE, Beier KT, et al. (2015) Intact-Brain Analyses Reveal Distinct Information Carried by SNc Dopamine Subcircuits. Cell 162: 635–647. doi: 10.1016/j.cell.2015.07.014 26232229