Spermatogenesis Studies Reveal a Distinct Nonsense-Mediated mRNA Decay (NMD) Mechanism for mRNAs with Long 3′UTRs
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Spermatogenesis Studies Reveal a Distinct Nonsense-Mediated mRNA Decay (NMD) Mechanism for mRNAs with Long 3′UTRs. PLoS Genet 12(5): e32767. doi:10.1371/journal.pgen.1005979
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https://doi.org/10.1371/journal.pgen.1005979
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1. Di Giammartino DC, Nishida K, Manley JL. Mechanisms and consequences of alternative polyadenylation. Mol Cell. 2011;43(6):853–66. doi: 10.1016/j.molcel.2011.08.017 21925375; PubMed Central PMCID: PMCPMC3194005.
2. Zhang H, Lee JY, Tian B. Biased alternative polyadenylation in human tissues. Genome Biol. 2005;6(12):R100. doi: 10.1186/gb-2005-6-12-r100 16356263; PubMed Central PMCID: PMCPMC1414089.
3. MacDonald CC, McMahon KW. Tissue-specific mechanisms of alternative polyadenylation: testis, brain, and beyond. Wiley Interdiscip Rev RNA. 2010;1(3):494–501. doi: 10.1002/wrna.29 21956945.
4. Wang L, Yi R. 3′UTRs take a long shot in the brain. Bioessays. 2014;36(1):39–45. doi: 10.1002/bies.201300100 24115048; PubMed Central PMCID: PMCPMC4067256.
5. Schweingruber C, Rufener SC, Zund D, Yamashita A, Muhlemann O. Nonsense-mediated mRNA decay—Mechanisms of substrate mRNA recognition and degradation in mammalian cells. Biochim Biophys Acta. 2013;1829(6–7):612–23. doi: S1874-9399(13)00027-8 [pii] doi: 10.1016/j.bbagrm.2013.02.005 23435113.
6. Peltz SW, Brown AH, Jacobson A. mRNA destabilization triggered by premature translational termination depends on at least three cis-acting sequence elements and one trans-acting factor. Genes Dev. 1993;7(9):1737–54. 8370523.
7. Lykke-Andersen S, Jensen TH. Nonsense-mediated mRNA decay: an intricate machinery that shapes transcriptomes. Nat Rev Mol Cell Biol. 2015. doi: 10.1038/nrm4063 26397022.
8. Boehm V, Haberman N, Ottens F, Ule J, Gehring NH. 3′ UTR Length and Messenger Ribonucleoprotein Composition Determine Endocleavage Efficiencies at Termination Codons. Cell Rep. 2014. Epub 2014/10/15. doi: 10.1016/j.celrep.2014.09.012 25310981.
9. Buhler M, Steiner S, Mohn F, Paillusson A, Muhlemann O. EJC-independent degradation of nonsense immunoglobulin-mu mRNA depends on 3′ UTR length. Nat Struct Mol Biol. 2006;13(5):462–4. 16622410.
10. Yepiskoposyan H, Aeschimann F, Nilsson D, Okoniewski M, Muhlemann O. Autoregulation of the nonsense-mediated mRNA decay pathway in human cells. RNA. 2011;17(12):2108–18. doi: rna.030247.111 [pii] doi: 10.1261/rna.030247.111 22028362.
11. Bao J, Vitting-Seerup K, Waage J, Tang C, Ge Y, Porse B, et al. UPF2-dependent nonsense-mediated mRNA decay pathway is essential for spermatogenesis by selectively eliminating longer 3′UTR transcripts. PLoS Genet. 2016; 12(3): e1005863.
12. Fanourgakis G, Lesche M, Akpinar M, Dahl A, Jessberger R. Chromatoid body protein TDRD6 supports long 3′ UTR triggered nonsense mediated mRNA decay. PLoS Genet. 2016; 12(3): e1005857.
13. Kotaja N, Bhattacharyya SN, Jaskiewicz L, Kimmins S, Parvinen M, Filipowicz W, et al. The chromatoid body of male germ cells: similarity with processing bodies and presence of Dicer and microRNA pathway components. Proc Natl Acad Sci U S A. 2006;103(8):2647–52. doi: 10.1073/pnas.0509333103 16477042; PubMed Central PMCID: PMCPMC1413789.
14. Meikar O, Vagin VV, Chalmel F, Sostar K, Lardenois A, Hammell M, et al. An atlas of chromatoid body components. RNA. 2014;20(4):483–95. doi: 10.1261/rna.043729.113 24554440; PubMed Central PMCID: PMCPMC3964910.
15. Gehring NH, Kunz JB, Neu-Yilik G, Breit S, Viegas MH, Hentze MW, et al. Exon-junction complex components specify distinct routes of nonsense-mediated mRNA decay with differential cofactor requirements. Mol Cell. 2005;20(1):65–75. 16209946.
Štítky
Genetika Reprodukčná medicínaČlánok vyšiel v časopise
PLOS Genetics
2016 Číslo 5
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