HIV Treatment-As-Prevention Research: Taking the Right Road at the Crossroads

1. UNAIDS Global AIDS response Progress report (2014) http://www.unaids.org/en/media/unaids/contentassets/documents/document/2014/GARPR_2014_guidelines_en.pdf. Accessed 17 July 2014.

2. Jones A, Cremin I, Abdullah F, Idoko J, Cherutich P, Kilonzo N, Rees H, Hallett T, O'Reilly K, Koechlin F, Schwartlander B, de Zalduondo B, Kim S, Jay J, Huh J, Piot P, Dybul M. Transformation of HIV from pandemic to low-endemic levels: a public health approach to combination prevention. Lancet 384 : 272–279. 2014 Apr 11. doi: 10.1016/S0140-6736(13)62230-8 24740087

3. McNairy ML, Cohen M, El-Sadr WM. Antiretroviral therapy for prevention is a combination strategy. Curr HIV/AIDS Rep. 2013 Jun;10(2):152–8. doi: 10.1007/s11904-013-0152-1 23371351

4. Granich RM, Gilks CF, Dye C, De Cock KM, Williams BG. Universal voluntary HIV testing with immediate antiretroviral therapy as a strategy for elimination of HIV transmission: a mathematical model. Lancet. 2009 Jan 3;373(9657):48–57. doi: 10.1016/S0140-6736(08)61697-9 19038438

5. Dodd PJ, Garnett GP, Hallett TB. Examining the promise of HIV elimination by 'test and treat' in hyperendemic settings. AIDS. 2010 Mar 13;24(5):729–35. doi: 10.1097/QAD.0b013e32833433fe 20154580

6. Celum C, Hallett TB, Baeten JM. HIV-1 prevention with ART and PrEP: mathematical modeling insights into resistance, effectiveness, and public health impact. J Infect Dis. 2013 Jul 15;208(2):189–91. doi: 10.1093/infdis/jit154 23570851

7. Cremin I, Alsallaq R, Dybul M, Piot P, Garnett G, Hallett TB. The new role of antiretrovirals in combination HIV prevention: a mathematical modelling analysis. AIDS. 2013 Jan 28;27(3):447–58 doi: 10.1097/QAD.0b013e32835ca2dd 23296196

8. Gardner EM, Young B. The HIV care cascade through time. Lancet Infect Dis. 2014 Jan;14(1):5–6. doi: 10.1016/S1473-3099(13)70272-X 24076276

9. Iwuji CC, Orne-Gliemann J, Tanser F, Boyer S, Lessells RJ, Lert F, Imrie J, Bärnighausen T, Rekacewicz C, Bazin B, Newell ML, Dabis F; ANRS 12249 TasP Study Group. Evaluation of the impact of immediate versus WHO recommendations-guided antiretroviral therapy initiation on HIV incidence: the ANRS 12249 TasP (Treatment as Prevention) trial in Hlabisa sub-district, KwaZulu-Natal, South Africa: study protocol for a cluster randomised controlled trial. Trials. 2013 Jul 23;14 : 230. doi: 10.1186/1745-6215-14-230 23880306

10. Hayes R, Ayles H, Beyers N, Sabapathy K, Floyd S, Shanaube K, Bock P, Griffith S, Moore A, Watson-Jones D, Fraser C, Vermund SH, Fidler S; HPTN 071 (PopART) Study Team. HPTN 071 (PopART): rationale and design of a cluster-randomised trial of the population impact of an HIV combination prevention intervention including universal testing and treatment—a study protocol for a cluster randomised trial. Trials. 2014 Feb 13;15 : 57. doi: 10.1186/1745-6215-15-57 24524229

11. Botswana Combination Prevention Project (BCPP). http://clinicaltrials.gov/show/NCT01965470. Accessed 17 July 2014.

12. Sustainable East Africa Research in Community Health (SEARCH). http://clinicaltrials.gov/show/NCT01864603. Accessed 17 July 2014.

13. Bärnighausen T, Eyal N, Wikler D. HIV treatment-as-prevention research at a crossroads. PLoS Med. 2014 Jun 3;11(6):e1001654. doi: 10.1371/journal.pmed.1001654 24892694

14. WHO (2014) Developing the 2013 WHOconsolidated antiretroviral guidelines. http://www.who.int/hiv/pub/journal_articles/arv2013-supplement-june2014/en/. Accessed 17 July 2014.

15. Cori A, Ayles H, Beyers N, Schaap A, Floyd S, Sabapathy K, Eaton JW, Hauck K, Smith P, Griffith S, Moore A, Donnell D, Vermund SH, Fidler S, Hayes R, Fraser C; HPTN 071 PopART Study Team. HPTN 071 (PopART): a cluster-randomized trial of the population impact of an HIV combination prevention intervention including universal testing and treatment: mathematical model. PLoS ONE. 2014 Jan 15;9(1):e84511. doi: 10.1371/journal.pone.0084511 24454728

16. McNairy ML, El-Sadr WM. The HIV Care Continuum: No Partial Credit Given. AIDS. 2012 Sep 10;26(14):1735–8 doi: 10.1097/QAD.0b013e328355d67b 22614888