Treatment of anaemia and iron deficiency in chronic heart failure

Česká verzia

Authors: J. Vítovec ¹; J. Špinar ^2,3; L. Špinarová ¹
Authors place of work: I. interní kardioangiologická klinika LF MU a FN u sv. Anny v Brně ¹; Interní kardiologická klinika LF MU Brno ²; Mezinárodní centrum klinického výzkumu, Brno ³
Published in the journal: Kardiol Rev Int Med 2014, 16(5): 364-369
Category: Cardiology Review

Summary

Iron deficiency is an important co‑ morbidity in patients with heart failure. A major factor in the pathogenesis of anaemia, it is also a separate condition with serious clinical consequences (e. g. impaired exercise capacity) and poor prognosis in heart failure patients. Experimental evidence suggests that iron therapy in iron‑ deficient patients may activate molecular pathways that can be cardio‑ protective. Clinical studies have demonstrated favourable effects of IV iron on the functional status, quality of life, and exercise capacity in HF patients. IV iron supplementation has become a novel therapy in HF patients with iron deficiency.

Keywords:
anaemia – iron deficiency – heart failure – therapy of anaemia

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