Facial Palsy

Česká verzia

Authors: M. Bojar
Authors place of work: Neurologická klinika 2. LF UK a FN v Motole, Praha
Published in the journal: Cesk Slov Neurol N 2007; 70/103(6): 613-624
Category: Minimonography

Věnováno památce prof. MUDr. Františka Hanzala, DrSc.

Summary

Facial palsy represents apparently a trivial mononeuropathy, which is considered to be identical with Bell’s palsy, the idiopathic facial palsy. It is ordinarily a manifestation of nuclear impairment or direct lesion of the facial nerve, a mononeuropathy, of an infectious or inflammatory origin. A relation between minimally 50 % peripheral facial palsies with herpes simplex virus 1, varicella zoster virus and bacterial infections, particularly borrelias and mycoplasmas, has been proved. Central and nuclear palsies are described with regard to complicated and underestimated differential diagnostics. The basic data on the heterogeneous entity of diseases associated with impairments of the intermediofacial nerve concerning infectious, demyelinating diseases, vascular, metabolic and degenerative diseases, tumors and injuries, are given. Data on epidemiology, etiology and diagnostic methods: laboratory, electrophysiological, neuroimaging, serologicalimmunological, and molecular–biological are presented. A survey of therapeutic procedures based on the use of anti-herpetic drugs, antibiotics, corticosteroids, symptomatic drugs and rehabilitation summarizes discrepant opinions of the effectiveness of therapy/management and clinical trials, which prevailingly do not meet the requirements of the evidence-based medicine.

Key words:
anti-herpetic drugs – Bell’s palsy – corticosteroids – CSF – facial palsy – herpes viruses – neuroborreliosis

Zdroje

1. Henner K. Speciální neurologie. 3. ed. Praha: Státní zdravotnické nakladatelství 1953.

2. Pechan J. Bellova obrna lícního nervu a její patogenetická léčba. Praha: Avicenum 1972.

3. Schmutzhard E. Viral infections of the CNS with special emphasis on herpes simplex infections. J Neurol 2001; 248: 469-477.

4. Allen D, Dunn L. Aciclovir or valaciclovir for Bell's palsy (idiopathic facial paralysis). Cochrane Database Syst Rev 2004; 4: CD001942.

5. Thomayer J. Pathologie a therapie nemocí vnitřních. Praha: Bursík & Kohout 1893.

6. van de Graaf RC, Nicolai JP. Bell's palsy before Bell: Cornelis Stalpart van der Wiel's observation of Bell's palsy in 1683. Otol Neurotol 2005; 26: 1235-1238.

7. Keller O, Jedlička P et al. Speciální neurologie. Praha: Galén&Karolinum 2005.

8. Nevšímalová S, Růžička E, Tichý J et al. Neurologie. Praha: Galén 2002.

9. Škeřík P. Náhlé a neodkladné stavy v otorinolaryngologii. Praha: Avicenum 1985.

10. De Diego-Sastre JI, Prim-Espada MP, Fernández-García F. The epidemiology of Bell's palsy. Rev Neurol 2005; 41: 287-290.

11. Rowlands S, Hooper R, Hughes R, Burney P. The epidemiology and treatment of Bell's palsy in the UK. Eur J Neurol 2002; 9: 63-67.

12. Holland NJ, Graeme MW. Recent developments in Bell's palsy. BMJ 2004; 329: 553-557.

13. ÚZIS ČR 2002.

14. Campbell KE, Brundage JF. Effects of climate, latitude, and season on the incidence of Bell's palsy in the US Armed Forces, October 1997 to September 1999. Am J Epidemiol 2002; 156: 32-39.

15. Duus P. Neurologisch - topische Diagnostik. Stuttgart: Georg Thieme Verlag 1983.

16. Mumenthaler M. Neurologic Differential Diagnosis. Stuttgart: Georg Thieme Verlag 1992.

17. Takahashi H, Hitsumoto Y, Honda N, Hato N, Mizobuchi M, Murakami S et al. Mouse model of Bell's palsy induced by reactivation of herpes simplex virus type 1. J Neuropathol Exp Neurol 2001; 60: 621-627.

18. Wakisaka H, Hato N, Honda N, Takahashi H, Kisaki H, Murakami S et al. Demyelination associated with HSV-1-induced facial paralysis. Exp Neurol 2002; 178: 68-79.

19. Eiffert H, Karsten A, Schlott T, Ohlenbusch A, Laskawi R, Hoppert M et al. Acute peripheral facial palsy in Lyme disease - a distal neuritis at the infection site. Neuropediatrics 2004; 35: 267-273.

20. Schnorpfeil F, Braune HJ. Nuclear facial palsy in multiple sclerosis: a case report. Electromyogr Clin Neurophysiol 1997; 37: 207-211.

21. Nowak DA, Linder S, Topka H. Diagnostic relevance of transcranial magnetic and electric stimulation of the facial nerve in the management of facial palsy. Clin Neurophysiol 2005; 116: 2051-2057.

22. Kress B, Griesbeck F, Stippich C, Bähren W, Sartor K. Bell palsy: quantitative analysis of MR imaging data as a method of predicting outcome. Radiology 2004; 230: 504-509.

23. Grosheva M, Guntinas-Lichius O. Significance of electromyography to predict and evaluate facial function outcome after acute peripheral facial palsy. Eur Arch Otorhinolaryngol 2007; 5(Epub). V tisku.

24. McCormick DP. Herpes-simplex virus as a cause of Bell's palsy. Lancet 1972; 29(1): 937-939.

25. Diaz GA, Rakita RM, Koelle DM. A case of Ramsay Hunt-like syndrome caused by herpes simplex virus type 2. Clin Infect Dis 2005; 40: 1545-1547.

26. Linder T, Bossart W, Bodmer D. Bell's palsy and Herpes simplex virus: fact or mystery? Otol Neurotol 2005; 26: 109-113.

27. Peitersen E. Bell's palsy: the spontaneous course of 2,500 peripheral facial nerve palsies of different etiologies. Acta Otolaryngol Suppl 2002; 549: 4-30.

28. Stjernquist-Desatnik A, Skoog E, Aurelius E. Detection of herpes simplex and varicella-zoster viruses in patients with Bell's palsy by the polymerase chain reaction technique. Ann Otol Rhinol Laryngol 2006; 115: 306-311.

29. Furuta Y, Aizawa H, Ohtani F, Sawa H, Fukuda S. Varicella-zoster virus DNA level and facial paralysis in Ramsay Hunt syndrome. Ann Otol Rhinol Laryngol 2004; 113: 700-705.

30. Kaygusuz I, Gödekmerdan A, Keleş E, Karlidağ T, Yalçin S, Yildiz M et al. The role of viruses in idiopathic peripheral facial palsy and cellular immune response. Am J Otolaryngol 2004; 25: 401-406.

31. Serrano P, Hernández N, Arroyo JA, de Llobet JM, Domingo P. Bilateral Bell palsy and acute HIV type 1 infection: report of 2 cases and review. Clin Infect Dis 2007; 44: 57-61 .

32. Černý R, Machala L. Neurologické komplikace HIV/AIDS. Praha: Karolinum 2007.

33. Jaquet Y, Maire R. Otoneurologic manifestations related to HIV infection: case report of facial paralysis and review of the literature. Rev Med Suisse Romande 2002; 122: 269-271.

34. Lotric-Furlan S, Cimperman J, Maraspin V, Ruzić-Sabljić E, Logar M, Jurca T et al. Lyme borreliosis and peripheral facial palsy. Wien Klin Wochenschr 1999; 111: 970-975.

35. Skogman BH, Croner S, Odkvist L. Acute facial palsy in children-a 2-year follow-up study with focus on Lyme neuroborreliosis. Int J Pediatr Otorhinolaryngol 2003; 67: 597-602.

36. Bagger-Sjöbäck D, Remahl S, Ericsson M. Long-term outcome of facial palsy in neuroborreliosis. Otol Neurotol 2005; 26: 790-795.

37. Jäämaa S, Salonen M, Seppälä I, Piiparinen H, Sarna S, Koskiniemi M. Varicella zoster and Borrelia burgdorferi are the main agents associated with facial paresis, especially in children. J Clin Virol 2003; 27: 146-151.

38. Bojar M. Borrelióza – postižení nervového systému. Med po promoci 2005; 6: 56-69.

39. Hulinska D, Votypka J, Plch J, Vlcek E, Valesová M, Bojar M et al. Molecular and microscopical evidence of Ehrlichia spp. and Borrelia burgdorferi sensu lato in patients, animals and ticks in the Czech Republic. New Microbiol 2002; 25: 437-448

40. Völter C, Helms J, Weissbrich B, Rieckmann P, Abele-Horn M. Frequent detection of Mycoplasma pneumoniae in Bell's palsy. Eur Arch Otorhinolaryngol 2004; 261: 400-404.

41. Said G. Infectious neuropathies. Neurol Clin 2007; 25: 115-137.

42. White ES, Lynch JP. Current and emerging strategies for the management of sarcoidosis. Expert Opin Pharmacother 2007; 8: 1293-1311.

43. Hoitsma E, Faber CG, Drent M, Sharma OP. Neurosarcoidosis: a clinical dilemma. Lancet Neurol 2004; 3: 397-407.

44. Fox PC. Autoimmune diseases and Sjogren's syndrome: an autoimmune exocrinopathy. Ann N Y Acad Sci 2007; 1098: 15-21.

45. Hughes RA, Cornblath DR. Guillaine-Barré Syndrome. Lancet 2005; 5(366): 1653-1666.

46. Kuwabara S. Guillain-Barré syndrome. Curr Neurol Neurosci Rep 2007;7: 57-62.

47. Odaka M, Yuki N, Yamada M, Koga M, Takemi T, Hirata K et al. Bickerstaff's brainstem encephalitis: clinical features of 62 cases and a subgroup associated with Guillain-Barré syndrome. Brain 2003; 126: 2279-2290.

48. Fukazawa T, Moriwaka F, Hamada K, Hamada T, Tashiro K. Facial palsy in multiple sclerosis. J Neurol 199; 244: 631-633.

49. Morrissey SP, Miller DH, Kendall BE, Kingsley DP, Kelly MA, Francis DA, MacManus DG, McDonald WI. The significance of brain magnetic resonance imaging abnormalities at presentation with clinically isolated syndromes suggestive of multiple sclerosis. A 5-year follow-up study. Brain 1993; 116:135-146.

50. van der Meijs AH, Tan IL, Barkhof F. Incidence of enhancement of the trigeminal nerve on MRI in patients with multiple sclerosis. Mult Scler 2002; 8: 64-67.

51. Koerbel A, Gharabaghi A, Safavi-Abbasi S, Tatagiba M, Samii M. Evolution of vestibular schwannoma surgery: the long journey to current success. Neurosurg Focus 2005; 18: e10.

52. Darrouzet V, Duclos JY, Liguoro D, Truilhe Y, De Bonfils C, Bebear JP. Management of facial paralysis resulting from temporal bone fractures: Our experience in 115 cases. Otolaryngol Head Neck Surg 2001; 125: 77-84.

53. Adour K, Wingerd J, Doty HE. Prevalence of concurrent diabetes mellitus and idiopathic facial paralysis [Bell's palsy]. Diabetes 1975; 24: 449-451.

54. Ghezzi A, Zaffaroni M. Neurological manifestations of gastrointestinal disorders, with particular reference to the differential diagnosis of multiple sclerosis. Neurol Sci 2001; 22(Suppl 2): 117-122.

55. Verzijl HT, van der Zwaag B, Lammens M, ten Donkelaar HJ, Padberg GW. The neuropathology of hereditary congenital facial palsy vs Möbius syndrome. Neurology 2005; 64: 649-653.

56. Rogers RS. Melkersson-Rosenthal syndrome and orofacial granulomatosis. Dermatol Clin 1996; 14: 371-379.

57. Verzijl HT, Valk J, de Vries R, Padberg GW. Radiologic evidence for absence of the facial nerve in Möbius syndrome. Neurology 2005; 64: 849-855.

58. da Silva Dal Pizzol T, Knop FP, Mengue SS. Prenatal exposure to misoprostol and congenital anomalies: systematic review and meta-analysis. Reprod Toxicol 2006; 22: 666-671.

59. Ambler Z, Bednařík J, Růžička E. Klinická neurologie. Praha: Triton 2004.

60. Pechan J, Vyhnánková E. Facial palsy and its conservative treatment - I. Anatomy, pathophysiology and examination of the facial nerve. II. Bell's palsy. III. Treatment of various kinds of peripheral facial palsies. Acta Univ Carol (Med) Praha. I 1978; 24 (5-6) :289-329, II 1978; 24 (7-8):3-36, III 1978; 24(7-8): 37-78.

61. Kanerva M, Mannonen L, Piiparinen H, Peltomaa M, Vaheri A, Pitkäranta A. Search for Herpesviruses in cerebrospinal fluid of facial palsy patients by PCR. Acta Otolaryngol 2007; 127: 775-779.

62. Hill MD, Midroni G, Goldstein WC, Deeks SL, Low DE, Morris AM. The spectrum of electrophysiological abnormalities in Bell's palsy. Can J Neurol Sci 2001; 28: 130-133.

63. Alberton DL, Zed PJ. Bell's palsy: a review of treatment using antiviral agents. Ann Pharmacother 2006; 40: 1838-1842.

64. Hughes RA. Treating nerves: from anecdote to systematic review. J R Soc Med 2003; 96: 432–435.

65. Salinas RA, Alvarez G, Ferreira J. Corticosteroids for Bell's palsy [idiopathic facial paralysis]. Cochrane Database Syst Rev 2004; 4: CD001942.

66. Grogan PM, Gronseth GS. Practice parameter: Steroids, acyclovir, and surgery for Bell's palsy (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology 2001; 56: 830-836.

67. Kawaguchi K, Inamura H, Abe Y, Koshu H, Takashita E, Muraki Y et al. Reactivation of herpes simplex virus type 1 and varicella-zoster virus and therapeutic effects of combination therapy with prednisolone and valacyclovir in patients with Bell's palsy. Laryngoscope 2007; 117:147-156.

68. Drobný M, Kurča E, Voško MR. Zvýšený výskyt periférnej obrny tvárového nervu. Cesk Slov Neurol N 2000; 1: 24–30.

69. Wormser GP, Nadelman RB, Dattwyler RJ, Dennis DT. Practice Guidelines for the Treatment of Lyme Disease. Clin Inf Dis 2000; 31(Suppl 1): 1–14.

70. Wormser GP, Ramanathan R, Nowakowski J, McKenna D, Holmgren D, Visintainer et al. Duration of antibiotic therapy for early Lyme disease. A randomized, double-blind, placebo-controlled trial. Ann Intern Med 2003;138: 697-704.

71. Taylor RS, Simpson IN. Review of treatment options for lyme borreliosis. J Chemother 2005; 17(Suppl 2): 3-16.

72. Ogrinc K, Logar M, Lotric-Furlan S, Cerar D, Ruzić-Sabljić E, Strle F. Doxycycline versus ceftriaxone for the treatment of patients with chronic Lyme borreliosis. Wien Klin Wochenschr 2006; 118: 696-701.

73. Buttress S, Herren K. Electrical stimulation and Bell’s palsy. Emerg Med J 2002; 19: 428.