#PAGE_PARAMS# #ADS_HEAD_SCRIPTS# #MICRODATA#

Protocol of Diagnostic and Treatment of Hyponatremia and Hypernatremia in Neurocritical Care


Authors: V. Špatenková 1;  P. Škrabálek 2
Authors place of work: Krajská nemocnice Liberec, a. s. Neurocentrum, Neurointenzivní jednotka 1;  Krajská nemocnice Liberec, a. s. Oddělení klinické biochemie 2
Published in the journal: Cesk Slov Neurol N 2015; 78/111(1): 34-37
Category: Review Article

Summary

Dysnatremias are common and serious complications in neurocritical care. They pose a risk mainly due to their effect on osmolality of extracellular fluids that influences the amount of water in intracellular fluids. Hyponatremia is associated with a risk of brain edema, while hypernatremia can cause brain dehydration. Hyponatremia occurs more frequently but hypernatremia is associated with poorer prognosis, serum sodium above 160 mmol/l is an independent risk factor for higher mortality. Risk factors for dysnatremias include: 1. brain damage, 2. therapeutic processes during neurocritical care, 3. iatrogenic conditions. One of the aims of neurocritical care is to prevent iatrogenic hypo/hypernatremias.

Key words:
hyponatremia – hypernatremia – neurocritical care

The authors declare they have no potential conflicts of interest concerning drugs, products, or services used in the study.

The Editorial Board declares that the manu­script met the ICMJE “uniform requirements” for biomedical papers.


Zdroje

1. Funk GC, Lindner G, Druml W, Metnitz B, Shwarz CH, Bauer P et al. Incidence and prognosis of dysnatremias present on ICU admission. Intensive Care Med 2010; 36(2): 304– 311. doi: 10.1007/ s00134‑ 009‑ 1692‑ 0.

2. Peters JP, Welt LG, Sims EA, Orloff J, Needham J. A salt‑ wasting syndrome associated with cerebral disease. Trans Assoc Am Physicians 1950; 63: 57– 64.

3. Schwartz WB, Bennett W, Curelop S, Bartter FC. A syndrome of renal sodium loss and hyponatremia probably resulting from inappropriate secretion of antidiuretic hormone. Am J Med 1957; 23(4): 529– 542.

4. Shoker AS. Application of the clearance concept to hyponatremic and hypernatremic disorders: a phenomenological analysis. Clin Chem 1994; 40(7): 1220– 1227.

5. Aiyagari V, Deibert E, Diringer M. Hypernatremia in the neurologic intensive care unit: how high is too high? J Crit Care 2006; 21(2): 163– 172.

6. Wong MF, Chin NM, Lew TW. Diabetes insipidus in neurosurgical patients. Ann Acad Med Singapore 1998; 27(3): 340– 343.

7. Spatenkova V, Bradac O, Kazda A, Suchomel P. Central diabetes insipidus is not a common and prognostical­­ly worse type of hypernatremia in neurointensive care. Neuro Endocrinol Lett 2011; 32(6): 879– 884.

8. Spasovski G, Vanholder R, Allolio B, Annane D, Ball S, Bichet D et al. Clinical practice guideline on diagnosis and treatment of hyponatraemia. Eur J Endocrinol 2014; 171(1): G1– G47. doi: 10.1530/ EJE‑ 13‑ 1020.

9. Spatenkova V, Bradac O, Skrabalek P. Outcome and frequency of sodium disturbances in neurocritically ill patients. Acta Neurol Belg 2013; 113(2): 139– 145. doi: 10.1007/ s13760‑ 012‑ 0137‑ 7.

10. Tisdall M, Crocker M, Watkiss J, Smith M. Disturbances of sodium in critically ill adult neurologic patients: a clinical review. J Neurosurg Anesthesiol 2006; 18(1): 57– 63.

11. Špatenkova V, Kazda A, Barsa P, Beneš V III, Škrabálek P, Králová D et al. Diagnostika hyponatrémií v neurointenzivní péči: úloha renálních funkčních parametrů. Cesk Slov Neurol N 2008; 71/ 104(2): 156– 162.

Štítky
Paediatric neurology Neurosurgery Neurology

Článok vyšiel v časopise

Czech and Slovak Neurology and Neurosurgery

Číslo 1

2015 Číslo 1
Najčítanejšie tento týždeň
Najčítanejšie v tomto čísle
Prihlásenie
Zabudnuté heslo

Zadajte e-mailovú adresu, s ktorou ste vytvárali účet. Budú Vám na ňu zasielané informácie k nastaveniu nového hesla.

Prihlásenie

Nemáte účet?  Registrujte sa

#ADS_BOTTOM_SCRIPTS#