Loneliness in the aetiology of somatic illnesses
Authors:
R. Ptáček 1; H. Kuželová 1,2; M. Vráblík 3
Authors place of work:
1. lékařská fakulta a Všeobecná fakultní nemocnice v Praze
; Psychiatrická klinika
Přednosta: prof. MUDr. Jiří Raboch, DrSc.
1; Ústav lékařské biologie a genetiky 2. LF UK
Přednosta: prof. MUDr. Milan Macek, DrSc.
2; 3. interní klinika 1. LF UK a VFN
Přednosta: prof. MUDr. Štěpán Svačina, DrSc., MBA
3
Published in the journal:
Prakt. Lék. 2011; 91(6): 325-327
Category:
Reviews
Summary
Loneliness is not only a psychological and social problem that affects an indiviual´s psyche, it is also a medical problem. Loneliness is a state similar to long-term stress, where the organism is exhausted. People who are lonely have sleep problems and report worse quality of rest, and it is thought they have an increased incidence of a number of somatic diseases. Many of the diseases result from decreased immunity, but the major problem in lonely people is a high incidence of cardiovascular diseases.
Key words:
loneliness, social isolation, somatic illnesses, cardiovascular disorders.
Zdroje
1. Aanes, M.M., Hetland, J., Pallesen, S., Mittelmark, M. B. Does loneliness mediate the stress-sleep quality relation? The Hordaland Health Study. Int. Psychogeriatr, 2011, 22, p. 1-9. [Epub ahead of print]
2. Bartels, M., Cacioppo, J., Hudziak, J. J., Boomsma, D.I. Genetic and environmental contributions to stability in loneliness throughout childhood. Am. J. Med. Gen.: Neuropsychiatric. genetics 2008, 147B(3), p. 385-391.
3. Cacioppo, J., Patric, W. Loneliness: human nature and the need for social connection. New York: W.W. Norton & Co., 2008.
4. Cacioppo, J.T., Hawkley, L.C., Crawford, L.E. et al. Loneliness and health: potential mechanisms. Psychosom. Med. 2002, 64, p. 407-417.
5. Caspi, A., Sugden, K., Moffitt, T., E. et al. Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene. Science 2003, 301, p. 386-389.
6. Cole, S.W., Mendoza, S.P., Capitanio, J.P. Social stress desensitizes lymphocytes to regulation by endogenous glucocorticoids: insights from in vivo cell trafficking dynamics in rhesus macaques. Psychosom. Med. 2009, 71(6), p. 591-597.
7. Doane, L.D., Adam, E.K. Loneliness and cortisol: momentary, day-to-day, and trait associations. Psychoneuroendocrinology 2010, 35(3), p. 430–441.
8. Dóci I., Hosák, L., Kovářová, M. Osamělost starých lidí jako sociální medicínský problém. Čas. Lék. čes. 2003, 142, s. 505-507.
9. Fragoso, C.A. V., Gill, T.M. Sleep complaints in community-living older persons: A multifactorial geriatric syndrome. J. Am. Geriatr. Soc. 2007, 55(11), p. 1853–1866.
10. Hawkley, L.C., Thisted, R.A., Masi, C.M., Cacioppo, J.T. Loneliness predicts increased blood pressure: 5-year cross-lagged analyses in middle-aged and older adults. Psychol. Aging 2010, 25(1), p. 132-141.
11. Hermesa, G.L., Delgado, B., Tretiakova, M. et al. Social isolation dysregulates endocrine and behavioral stress while increasing malignit burden of spontaneous mammary tumors. Proc. Natl. Acad. Sci. USA 2009, 106(52), p. 22393-22398.
12. Heinrich, L.M., Gullone, E. The clinical significance of loneliness: a literature review. Clin. Psychol. Rev. 2006, 26, p. 695-718.
13. Honzák, R., Seifert, B. Úzkostný pacient s kardiovaskulárními příznaky. Prakt. Lék. 2005. 85(2), s. 102-106.
14. Kuzelova, H., Ptacek, R., Macek, M. Jr. The serotonin transporter gene (5-HTT) variant and psychiatric disorders. Neuroendocrino.l Lett. 2010, 31(1), p. 4-10.
15. Kuželová, H., Ptáček, R., Macek, M. Jr. Polymorfismus genu pro serotoninový transportér 5-HTT v etiologii psychiatrických onemocnění. Čes. slov. Psych. 2010, 106(2), p. 98-104.
16. Nausheen, B., Gidron, Y., Gregg, A. et al. Loneliness, social support and cardiovascular reactivity to laboratory stress. Stress 2007, 10(1), p. 37-44.
17. Peichlová, J., Pavlata, M. Deprese a kardiovaskulární onemocnění. Prakt. Lék. 2002, 7, s. 385-388.
18. Segrin, C., Domschke, T. Social support, loneliness, recuperative processes, and their direct and indirect effects on health. Health Commun. 2011, 26(3), p. 221-232.
19. Smith, S.S., Kozak, N., Sullivan, K.A. An investigation of the relationship between subjective sleep quality, loneliness and mood in an Australian sample: Can daily routine explain the links? Int. J. Soc. Psychiatry. Published online before print November 24, 2010, doi: 10.1177/0020764010387551.
20. Steptoe, A., Owen, N., Kunz-Ebrecht, S.R., Brydon, L. Loneliness and neuroendocrine, cardiovascular, and inflammatory stress responses in middle-aged men and women. Psychoneuroendocrinology 2004, 29(5), p. 593-611.
21. Thurston, R.C., Kubzansky, L.D. Women, loneliness, and incident coronary heart disease. Psychosom. Med. 2009, 71(8), p. 836-842.
22. van Roekel, E., Scholte, R.H., Verhagen, M. et al. Loneliness in adolescence: gene x environment interactions involving the serotonin transporter gene. J. Child. Psychol. Psychiatry 2010, 51(7), p. 747-754.
23. Wilson, R.S., Krueger, K.R., Arnold, S.E. et al. Loneliness and risk of Alzheimer disease. Arch. Gen. Psychiatry 2007, 64, p. 234–240.
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