Health effects of supplementation of carnosine and beta-alanine in the elderly population

Česká verzia

Authors: Česák Ondřej; Študent Vladimír jr.; Vidlář Aleš
Authors place of work: Urologická klinika LF UP a FN Olomouc
Published in the journal: Geriatrie a Gerontologie 2022, 11, č. 4: 171-175
Category: Review Article

Summary

Globally, the population is ageing. Healthcare should prepare for this situation and look for ways to improve, prolong and improve the quality of life of the ageing population. Ageing is associated with changes in physiological functions, such as changes in skeletal muscle activity, loss of muscle mass and reduced strength, changes in bone tissue and a decline in sensory and cognitive functions.

Deterioration of the human body in old age may be associated with reduced tissue concentrations of carnosine, whereby the protection of cell membranes from oxidative damage is reduced. It seems that by consuming foods rich in carnosine or by enriching the diet with β-alanine, these degenerative processes could be slowed down.

The amino acid β-alanine is one of the world‘s most widely used sports supplements to improve exercise performance because it is a precursor of carnosine, which is important for striated muscle function. This paper aims to report on supplementation with β-alanine, a precursor of carnosine, which represents one of the few proven dietary interventions that could help not only in the fight against aging and muscle loss, but also in the prevention of other diseases such as senile cataracts, neurodegenerative diseases and peripheral artery and vein disease.

Keywords:

sarcopenia – Peripheral vascular disease – cataract – Beta-alanine – carnosine – cognitive funtions

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