Allergen Challenge Used to Diagnose Food Allergy – Oral Allergy Syndrome
Authors:
H. Vávrová; M. Heroldová; P. Kučera
Authors place of work:
Oddělení alergologie a klinické imunologie, Ústav imunologie 3. LF UK a FNKV, Praha
Published in the journal:
Čas. Lék. čes. 2008; 147: 355-359
Category:
Review Article
Summary
Food allergy is an immune mediated unwanted side effect to food. All types of hypersensitivity can be involved; the most prevalent is IgE mediated one. The diagnosis is based on the history, skin tests with allergens and detection of specific IgE. These procedures are not highly predictive for clinical reactivity to food allergens, true clinical reactivity can be confirmed by allergen challenge. Oral allergy syndrome is represented by mostly subjective symptoms in oral cavity, usually triggered by fruit or vegetable allergens, cross-reacting with pollen allergens. This cross-reactivity is based on protein homology and immunologic similarity. To confirm the diagnosis of food allergy, the „golden standard“ is the double blind placebo controlled food challenge. The basic features of this test are discussed, particularly in the diagnosis of the oral allergy syndrome. Controlled food challenge is a useful test for patient’s diagnosis confirmation, evaluation of other diagnostic tests or evaluation of food allergenicity.
Key words:
oral allergy syndrome, food allergen, double blind placebo controlled food challenge.
Zdroje
1. Bruijnzeel-Koomen, C. et al.: Adverse reactions to food. Allergy, 1995, 50, s. 623–635.
2. Ko, J., Mayer, L.: Oral tolerance: lessons on treatment of food allergy. Eur. J. Gastroenterol. Hepatol., 2005, 17, s. 1299–1303.
3. Van Wijk, F., Knippels, L.: Initiating mechanisms of food allergy: Oral tolerance versus allergic sensitization. Biomed. Pharmacother., 2007, 61, s. 8–20.
4. Fuchs, M.: Přecitlivělost (hypersenzitivita) na kravské mléko. Alergie a intolerance. Alergie, 2007, 2, s. 149–159.
5. Fuchs, M.: Potravinová alergie. In: Špičák, V., Panzner, P. et al.: Alergologie. Praha, Galén, 2004, s. 270.
6. Bock, S. A.: Prospective appraisal of complaints of adverse reactions to foods in children during the first 3 years of life. Pediatrics, 1987, 79, s. 683–688.
7. Kanny, G., Moneret-Vautrin, D. A., Flabbee, J. et al.: Population study of food allergy in France. J. Allergy Clin. Immunol., 2001, 108, s. 133–140.
8. Tay, S. S. et al.: T cell proliferation and cytokine responses to ovalbumin and ovomucoid detected in children with and without egg allergy. Clin. Exp. Allergy, 2007, 37, s. 1519–1527.
9. Tuft, I., Blumstein, G. I.: Studies in food allergy. II. Senzitization to fresh fruits: clinical and experimental observations. J. Allergy, 1942, 13, s. 574–581.
10. Sancho, A. I., Rigby, N. M., Zuidmeer, L. et al.: The effect of thermal processing on the IgE reactivity of the non–specific lipid transfer protein from apple, Mal d 3. Allergy, 2005, 60, s. 1262–1268.
11. Asero, R.: Effects of birch pollen-specific immunotherapy on apple allergy in birch polen-hypersensitive patiens. Clin. Exp. Allergy, 1998, 28, s. 1368–1373.
12. Bucher, X., Eichler, W. J., Dahinden, C. A., Helbling, A.: Effect of tree pollen specific subcutaneous immunotherapy on the oral allergy syndrome to apple and hazelnut. Allergy, 2004, 59, s. 1272–1276.
13. Moller, C.: Effect of pollen immunotherapy on food hypersensitivity in children with birch pollinosis. Ann Allergy, 1989, 62, s. 343–345.
14. Hansen, K. S., Khinchi, M. S., Skov, P. S. et al.: Food allergy to apple and specific immunotherapy with birch pollen. Mol. Nutr. Food. Res., 2004, 48, s. 441–448.
15. Ma, Y., Gadermaier,G., Bohle, B. et al: Mutational analysis of amino acid positions crucial for IgE–binding epitopes of the major apple (Malus domestica) allergen, Mal d 1. Int Arch. Allergy Immunol., 2006, 139, s. 53–62.
16. Fernández-Rivas, M., Bolhaar, S., González-Mancebo, E. et al.: Apple allergy across Europe: How allergen senzitization profiles determine the clinical expression of allergies to plant foods. J. Allergy Clin. Immunol., 2006, 118, s. 481–488.
17. Ferrer, A., Carbes, J., Gallego, T. et al.: Characterization and improvement of apple extracts for the diagnosis of apple IgE–mediated allergy. Ann. Allergy Asthma Immunol., 2005, 95, s. 462–467.
18. Ma, Y., Zuidmeer, L., Bohle, B. et al.: Characterization of recombinant Mal d 4 and its application for component-resolved diagnosis of apple allergy. Clin. Exp. Allergy, 2006, 36, s. 1087–1096.
19. Ballmer-Weber, B. K, Wangorsch, A., Bohle, B. et al.: Component-resolved in vitro diagnosis in carrot allergy: Does the use of recombinant carrot allergens improve the reliability of the diagnostic procedure? Clin. Exp. Allergy, 2005, 35, s. 970–978.
20. Ballmer-Weber, B. K., Wüthrich, B., Wangorsch, A. et al.: Carrot allergy: double blinded, placebo controlled food chalenge and identification of allergens. J. Allergy Clin. Immunol., 2001,108, s. 301–307.
21. Sampson, H., Ho, D. G.: Relationship between food-specific IgE concentrations and the risk of positive food challenges in children and adolescents. J. Allergy Clin. Immunol., 1997, 100, s. 444–451.
22. Corrigan, Ch., Rak, S.: Food allergy. Allergy, Mosby, 2004, s. 59–72.
23. Niggemann, B., Beyer, K.: Pitfalls in double-blind, placebo-controlled oral food challenges. Allergy, 2007, 62, s. 729–732.
24. Rance, F., Dutau, G.: Labial food challenge in children with food allergy. Pediatr. Allergy Immunol., 1997, 8, s. 41–44.
25. Ortolani, C., Ispano, M., Pastorello, E. A. et al.: Comparison of results of skin prick tests (with fresh foods and commercial food extracts) and RAST in 100 patients with oral allergy syndrom. J. Allergy Clin. Immunol., 1989, 83, s. 683–690.
26. Bindsley-Jensen, C., Ballmer-Weber, B. K., Bengtsson, U. et al.: Standardization of food challenges in patients with immediate reactions to foods-position paper from the European Academy of Allergology and Clinical Imunology. Allergy, 2004, 59, s. 690–697.
27. Ballmer-Weber, B. K., Vieths, S., Luttkopf, D. et al.: Celery allergy confirmed by double-blind, placebo-controlled food challenge: a clinical study in 32 subjects with a history of averse reactions to celery root. J. Allergy Clin. Immunol., 2000, 106, s. 373–378.
28. Ballmer-Weber, B. K., Hoffmann, A., Wuthrich, B. et al.: Influence of food processing on the allergenicity of celery: DBPCFC with celery spice and cooked celery in patiens with celery allergy. Allergy, 2002, 57, s. 228–235.
29. Rudeschko, O., Fahlbusch, B., Henzgen, M. et al.: Investigation of the stability of apple allergen extracts. Allergy, 1995, 50, s. 575–580.
30. Hsieh, L. S., Moos, M. J., Lin, Y.: Characterization of apple 18 and 31 kD allergens by microsequencing and evaluation of their content during storage and ripening. J. Allergy Clin. Immunol., 1995, 96, s. 960–970.
31. Vieths, S., Jankiewicz, A., Schoening, B., Aulepp, H.: Apple allergy: the IgE binding potency of apple strains is related to the occurrence of the 18-kDa allergen. Allergy, 1994, 49, s. 262–271.
32. Skamstrup Hansen, K., Vestergaqard, H. Stahl Skov, P. et al.: Double-blind, placebo controlled food challenge with apple. Allergy, 2001, 56, s. 109–117.
33. Marcucci, F., Frati, F., Sensi, L. et al.: Evaluation of food-pollen cross-reactivity by nose-mouth cross-challenge in pollinosis with oral allergy syndrome. Allergy, 2005, 60, s. 501–505.
34. Ettlerová, K., Kohout, P.: Diagnostické možnosti potravinové alergie a intolerance. Alergie, 2000, 3, s. 190–195.
Štítky
Addictology Allergology and clinical immunology Angiology Audiology Clinical biochemistry Dermatology & STDs Paediatric gastroenterology Paediatric surgery Paediatric cardiology Paediatric neurology Paediatric ENT Paediatric psychiatry Paediatric rheumatology Diabetology Pharmacy Vascular surgery Pain management Dental HygienistČlánok vyšiel v časopise
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