Burning Down the House: Cellular Actions during Pyroptosis

1. NeteaMG, SimonA, van de VeerdonkFLV, KullbergBJ, Van der MeerJ, et al. (2010) IL-1beta Processing in Host Defense: Beyond the Inflammasomes. PLoS Pathog 6: e1000661 doi:10.1371/journal.ppat.1000661

2. MiaoEA, LeafIA, TreutingPM, MaoDP, DorsM, et al. (2010) Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria. Nat Immunol 11: 1136–1142.

3. CooksonBT, BrennanMA (2001) Pro-inflammatory programmed cell death. Trends Microbiol 9: 113–114.

4. LamkanfiM, KannegantiT-D, Van DammeP, BergheTV, VanoverbergheI, et al. (2008) Targeted peptidecentric proteomics reveals caspase-7 as a substrate of the caspase-1 inflammasomes. Mol Cell Proteomics 7: 2350–2363.

5. ShaoW, YeretssianG, DoironK, HussainSN, SalehM (2007) The caspase-1 digestome identifies the glycolysis pathway as a target during Infection and Septic Shock. J Biol Chem 282: 36321–36329.

6. WalshJG, LogueSE, LüthiAU, MartinSJ (2011) Caspase-1 Promiscuity Is Counterbalanced by Rapid Inactivation of Processed Enzyme. J Biol Chem 286: 32513–32524.

7. AgardNJ, MaltbyD, WellsJA (2010) Inflammatory stimuli regulate caspase substrate profiles. Mol Cell Proteomics 9: 880–893.

8. FinkSL, CooksonBT (2006) Caspase-1-dependent pore formation during pyroptosis leads to osmotic lysis of infected host macrophages. Cell Microbiol 8: 1812–1825.

9. GalluzziL, VitaleI, AbramsJM, AlnemriES, BaehreckeEH, et al. (2012) Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012. Cell Death Differ 19: 107–120.

10. LaRockCN, CooksonBT (2012) The Yersinia Virulence Effector YopM Binds Caspase-1 to Arrest Inflammasome Assembly and Processing. Cell Host Microbe 12: 799–805.

11. BergsbakenT, CooksonBT (2007) Macrophage Activation Redirects Yersinia-Infected Host Cell Death from Apoptosis to Caspase-1-Dependent Pyroptosis. PLoS Pathog 3: e161 doi:10.1371/journal.ppat.0030161

12. BergsbakenT, FinkSL, CooksonB (2009) Pyroptosis: host cell death and inflammation. Nat Rev Microbiol 7: 99–109.

13. ChenGY, NuñezG (2010) Sterile inflammation: sensing and reacting to damage. Nat Rev Immunol 10: 826–837.

14. LamkanfiM, SarkarA, Vande WalleL, VitariAC, AmerAO, et al. (2010) Inflammasome-dependent release of the alarmin HMGB1 in endotoxemia. J Immunol 185: 4385–4392.

15. von MoltkeJ, TrinidadNJ, MoayeriM, KintzerAF, WangSB, et al. (2012) Rapid induction of inflammatory lipid mediators by the inflammasome in vivo. Nature 490: 107–111.

16. MacKenzieA, WilsonHL, Kiss-TothE, DowerSK, NorthRA, et al. (2001) Rapid secretion of interleukin-1B by microvesicle shedding. Immunity 8: 825–835.

17. BergsbakenT, FinkSL, den HartighAB, LoomisWP, CooksonBT (2011) Coordinated Host Responses during Pyroptosis: Caspase-1-Dependent Lysosome Exocytosis and Inflammatory Cytokine Maturation. J Immunol 187: 2748–2754.

18. KellerM, RueggA, WernerS, BeerH (2008) Active caspase-1 is a regulator of unconventional protein secretion. Cell 132: 818–831.

19. GroßO, YazdiAS, ThomasCJ, MasinM, HeinzLX, et al. (2012) Inflammasome activators induce interleukin-1α secretion via distinct pathways with differential requirement for the protease function of caspase-1. Immunity 36: 388–400.

20. ReddyA, CalerEV, AndrewsNW (2001) Plasma Membrane Repair Is Mediated by Ca2+-Regulated Exocytosis of Lysosomes. Cell 106: 157–169.

21. SuzukiT, FranchiL, TomaC, AshidaH, OgawaM, et al. (2007) Differential regulation of caspase-1 activation, pyroptosis, and autophagy via Ipaf and ASC in Shigella-infected macrophages. PLoS Pathog 3: e111 doi:10.1371/journal.ppat.0030111

22. NakahiraK, HaspelJA, RathinamVAK, LeeS-J, DolinayT, et al. (2011) Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome. Nat Immunol 8: 222–230.

23. HarrisJ, HartmanM, RocheC, ZengSG, O'SheaA, et al. (2011) Autophagy controls IL-1β secretion by targeting pro-IL-1β for degradation. J Biol Chem 286: 9587–9597.

24. ShiC-S, ShenderovK, HuangN-N, KabatJ, Abu-AsabM, et al. (2012) Activation of autophagy by inflammatory signals limits IL-1 [beta] production by targeting ubiquitinated inflammasomes for destruction. Nat Immunol 13: 255–263.

25. DupontN, JiangS, PilliM, OrnatowskiW, BhattacharyaD, et al. (2011) Autophagy-based unconventional secretory pathway for extracellular delivery of IL-1β. EMBO J 30: 4701–4711.

26. ByrneBG, DubuissonJ-F, JoshiAD, PerssonJJ, SwansonMS (2013) Inflammasome Components Coordinate Autophagy and Pyroptosis as Macrophage Responses to Infection. MBio 4: e00620–00612.

27. GurcelL, AbramiL, GirardinS, TschoppJ, van der GootFG (2006) Caspase-1 activation of lipid metabolic pathways in response to bacterial pore-forming toxins promotes cell survival. Cell 126: 1135–1145.

28. KayagakiN, WarmingS, LamkanfiM, WalleLV, LouieS, et al. (2011) Non-canonical inflammasome activation targets caspase-11. Nature 479: 117–121.

29. AachouiY, LeafIA, HagarJA, FontanaMF, CamposCG, et al. (2013) Caspase-11 Protects Against Bacteria That Escape the Vacuole. Science 339: 975–978.

30. NeteaMG, NoldMF, JoostenLA, OpitzB, van de VeerdonkFLV, et al. (2009) Differential requirement for the activation of the inflammasome for processing and release of IL-1B in monocytes and macrophages. Blood 113: 2324–2335.

31. HolzingerD, GieldonL, MysoreV, NippeN, TaxmanDJ, et al. (2012) Staphylococcus aureus Panton-Valentine leukocidin induces an inflammatory response in human phagocytes via the NLRP3 inflammasome. J Leukoc Biol 92: 1069–1081.