The application of IPF (Immature platelet fraction) in laboratory diagnostics

Česká verzia

Authors: M. Ryzí; J. Gumulec
Authors place of work: Ústav klinické hematologie FN Ostrava, přednosta prim. MU Dr. Jaromír Gumulec
Published in the journal: Vnitř Lék 2010; 56(Supplementum 1): 109-111
Category: 16th Parizek's Days, Ostrava-Poruba, March 25th –26th 2010

Summary

Young platelets – reticulated platelets – are a marker of the thromopoiesis. The determination of reticulated platelets can be used to a laboratory diagnosis of thrombocytopenias and to the monitoring of a platelet kinetics after the chemotherapy and after bone marrow transplantation. Reticulated platelets have been measured by flow cytometry. This determination has been expensive, time spending and it has been never standardise. Now it is possible to measure young platelets as a part of the full blood count by the haematological analyser Sysmex XE 5 000. Reticulated platelets are named as IPF (Immature platelet fraction) in this analyser.

Key words:
reticulated platelets – IPF – throbocytopenia

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