The course of differentiated thyroid microcarcinoma in patients treated by different therapeutic strategies

Česká verzia

Authors: Marianna Grigerová ^1,2; Martin Griger ³; Emília Mojtová ^1,2; Ján Podoba ^1,2
Authors place of work: Klinika endokrinológie LF SZU, Bratislava, Slovenská republika ¹; Onkologický ústav svätej Alžbety, s. r. o, Bratislava, Slovenská republika ²; EuroPainClinics Bratislava, Slovenská republika ³
Published in the journal: Vnitř Lék 2016; 62(Suppl 3): 17-21
Category: Original Contributions

Summary

Low risk differentiated thyroid microcarcinoma therapy is a controversial area of thyroid tumor management. Major international medical societies and reputable institutes consider lobectomy to be sufficient therapeutic intervention for the pT1a cN0cM0 stage of papillary thyroid microcarcinoma. However different views and therapeutic strategies exist and result in unnecessary overtreatment and worsening of patient’s quality of life. We researched the course of the differentiated thyroid microcarcinoma in patients using different therapeutic strategies: lobectomy, total thyroidectomy, total thyroidectomy with central compartment prophylactic lymphadenectomy and total thyroidectomy followed by radioactive iodine treatment. Apart from an excellent prognosis we did not find out any clinically significant differences in the course of the disease. We can conclude that lobectomy is sufficient therapeutic intervention for patients with differentiated thyroid microcarcinoma without known metastases.

Key words:
differentiated thyroid microcarcinoma – management – overtreatment – the course of the disease

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