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Too Much Cleavage of Cyclin E Promotes Breast Tumorigenesis


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Vyšlo v časopise: Too Much Cleavage of Cyclin E Promotes Breast Tumorigenesis. PLoS Genet 8(3): e32767. doi:10.1371/journal.pgen.1002623
Kategorie: Perspective
prolekare.web.journal.doi_sk: https://doi.org/10.1371/journal.pgen.1002623

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Zdroje

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18. DuongMTAkliSWeiCWingateHFLiuW 2012 LMW-E/CDK2 deregulates acinar morphogenesis, induces tumorigenesis and associates with the activated b-Raf-ERK1/2-mTOR pathway in breast cancer patients. PLoS Genet 8 e1002538 doi:10.1371/journal.pgen.1002538

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22. DelkNAHuntKKKeyomarsiK 2009 Altered subcellular localization of tumor-specific cyclin E isoforms affects cyclin-dependent kinase 2 complex formation and proteasomal regulation. Cancer Res 69 2817 2825

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24. CarusoJAHuntKKKeyomarsiK 2010 The neutrophil elastase inhibitor elafin triggers rb-mediated growth arrest and caspase-dependent apoptosis in breast cancer. Cancer Res 70 7125 7136

Štítky
Genetika Reprodukčná medicína

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PLOS Genetics


2012 Číslo 3
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Autori: MUDr. Tomáš Ürge, PhD.

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