Discovery of an Ebolavirus-Like Filovirus in Europe
Filoviruses, amongst the most lethal of primate pathogens, have only been reported as natural infections in sub-Saharan Africa and the Philippines. Infections of bats with the ebolaviruses and marburgviruses do not appear to be associated with disease. Here we report identification in dead insectivorous bats of a genetically distinct filovirus, provisionally named Lloviu virus, after the site of detection, Cueva del Lloviu, in Spain.
Vyšlo v časopise:
Discovery of an Ebolavirus-Like Filovirus in Europe. PLoS Pathog 7(10): e32767. doi:10.1371/journal.ppat.1002304
Kategorie:
Research Article
prolekare.web.journal.doi_sk:
https://doi.org/10.1371/journal.ppat.1002304
Souhrn
Filoviruses, amongst the most lethal of primate pathogens, have only been reported as natural infections in sub-Saharan Africa and the Philippines. Infections of bats with the ebolaviruses and marburgviruses do not appear to be associated with disease. Here we report identification in dead insectivorous bats of a genetically distinct filovirus, provisionally named Lloviu virus, after the site of detection, Cueva del Lloviu, in Spain.
Zdroje
1. TownerJSSealyTKKhristovaMLAlbarinoCGConlanS 2008 Newly discovered ebola virus associated with hemorrhagic fever outbreak in Uganda. PLoS Pathog 4 e1000212
2. BarretteRWMetwallySARowlandJMXuLZakiSR 2009 Discovery of swine as a host for the Reston ebolavirus. Science 325 204 206
3. LeroyEMEpelboinAMondongeVPourrutXGonzalezJP 2009 Human Ebola outbreak resulting from direct exposure to fruit bats in Luebo, Democratic Republic of Congo, 2007. Vector Borne Zoonotic Dis 9 723 728
4. LeroyEMKumulunguiBPourrutXRouquetPHassaninA 2005 Fruit bats as reservoirs of Ebola virus. Nature 438 575 576
5. SwanepoelRLemanPABurtFJZachariadesNABraackLE 1996 Experimental inoculation of plants and animals with Ebola virus. Emerg Infect Dis 2 321 325
6. SwanepoelRSmitSBRollinPEFormentyPLemanPA 2007 Studies of reservoir hosts for Marburg virus. Emerg Infect Dis 13 1847 1851
7. TownerJSAmmanBRSealyTKCarrollSAComerJA 2009 Isolation of genetically diverse Marburg viruses from Egyptian fruit bats. PLoS Pathog 5 e1000536
8. QuetglasJGonzalezFPazO 2003 Estudian la extraña mortandad de miles de murcielago de cuevas. Quercus 203 50
9. AppletonBRMcKenzieJAChristidisL 2004 Molecular systematics and biogeography of the bent-wing bat complex Miniopterus schreibersii (Kuhl, 1817) (Chiroptera: Vespertilionidae). Mol Phylogenet Evol 31 431 439
10. HartyRNBrownMEWangGHuibregtseJHayesFP 2000 A PPxY motif within the VP40 protein of Ebola virus interacts physically and functionally with a ubiquitin ligase: implications for filovirus budding. Proc Natl Acad Sci U S A 97 13871 13876
11. JasenoskyLDNeumannGLukashevichIKawaokaY 2001 Ebola virus VP40-induced particle formation and association with the lipid bilayer. J Virol 75 5205 5214
12. VolchkovVEBlinovVMNetesovSV 1992 The envelope glycoprotein of Ebola virus contains an immunosuppressive-like domain similar to oncogenic retroviruses. FEBS Lett 305 181 184
13. YaddanapudiKPalaciosGTownerJSChenISariolCA 2006 Implication of a retrovirus-like glycoprotein peptide in the immunopathogenesis of Ebola and Marburg viruses. FASEB J 20 2519 2530
14. ReidSPLeungLWHartmanALMartinezOShawML 2006 Ebola virus VP24 binds karyopherin alpha1 and blocks STAT1 nuclear accumulation. J Virol 80 5156 5167
15. FagerlundRMelenKKinnunenLJulkunenI 2002 Arginine/lysine-rich nuclear localization signals mediate interactions between dimeric STATs and importin alpha 5. J Biol Chem 277 30072 30078
16. SuzukiYGojoboriT 1997 The origin and evolution of Ebola and Marburg viruses. Mol Biol Evol 14 800 806
17. KuhnJHBeckerSEbiharaHGeisbertTWJohnsonKM 2010 Proposal for a revised taxonomy of the family Filoviridae: classification, names of taxa and viruses, and virus abbreviations. Arch Virol 155 2083 2103
18. SanchezATrappierSGMahyBWPetersCJNicholST 1996 The virion glycoproteins of Ebola viruses are encoded in two reading frames and are expressed through transcriptional editing. Proc Natl Acad Sci U S A 93 3602 3607
19. VolchkovVEBeckerSVolchkovaVATernovojVAKotovAN 1995 GP mRNA of Ebola virus is edited by the Ebola virus polymerase and by T7 and vaccinia virus polymerases. Virology 214 421 430
20. VolchkovaVAKlenkHDVolchkovVE 1999 Delta-peptide is the carboxy-terminal cleavage fragment of the nonstructural small glycoprotein sGP of Ebola virus. Virology 265 164 171
21. MehediMFalzaranoDSeebachJHuXCarpenterMS 2011 A new Ebola virus nonstructural glycoprotein expressed through RNA editing. J Virol 85 5406 5414
22. FormentyPBoeschCWyersMSteinerCDonatiF 1999 Ebola virus outbreak among wild chimpanzees living in a rain forest of Cote d'Ivoire. J Infect Dis 179 Suppl 1 S120 126
23. SanchezAKsiazekTGRollinPEPetersCJNicholST 1995 Reemergence of Ebola virus in Africa. Emerg Infect Dis 1 96 97
24. LeroyEMSouquiereSRouquetPDrevetD 2002 Re-emergence of ebola haemorrhagic fever in Gabon. Lancet 359 712
25. LeirsHMillsJNKrebsJWChildsJEAkaibeD 1999 Search for the Ebola virus reservoir in Kikwit, Democratic Republic of the Congo: reflections on a vertebrate collection. J Infect Dis 179 Suppl 1 S155 163
26. TownerJSPourrutXAlbarinoCGNkogueCNBirdBH 2007 Marburg virus infection detected in a common African bat. PLoS One 2 e764
27. PourrutXSourisMTownerJSRollinPENicholST 2009 Large serological survey showing cocirculation of Ebola and Marburg viruses in Gabonese bat populations, and a high seroprevalence of both viruses in Rousettus aegyptiacus. BMC Infect Dis 9 159
28. FrickWFPollockJFHicksACLangwigKEReynoldsDS 2010 An emerging disease causes regional population collapse of a common North American bat species. Science 329 679 682
29. PetersonATBauerJTMillsJN 2004 Ecologic and geographic distribution of filovirus disease. Emerg Infect Dis 10 40 47
30. BelyiVALevineAJSkalkaAM 2010 Unexpected inheritance: multiple integrations of ancient bornavirus and ebolavirus/marburgvirus sequences in vertebrate genomes. PLoS Pathog 6 e1001030
31. TaylorDJLeachRWBruennJ 2010 Filoviruses are ancient and integrated into mammalian genomes. BMC Evol Biol 10 193
32. PalaciosGQuanPLJabadoOJConlanSHirschbergDL 2007 Panmicrobial oligonucleotide array for diagnosis of infectious diseases. Emerg Infect Dis 13 73 81
33. TrifonovVRabadanR 2010 Frequency analysis techniques for identification of viral genetic data. MBio 1 e00156 10
34. GouyMGuindonSGascuelO 2010 SeaView version 4: A multiplatform graphical user interface for sequence alignment and phylogenetic tree building. Mol Biol Evol 27 221 224
35. RonquistFHuelsenbeckJP 2003 MrBayes 3: Bayesian phylogenetic inference under mixed models. Bioinformatics 19 1572 1574
36. DrummondAJRambautA 2007 BEAST: Bayesian evolutionary analysis by sampling trees. BMC Evol Biol 7 214
Štítky
Hygiena a epidemiológia Infekčné lekárstvo LaboratóriumČlánok vyšiel v časopise
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