Host and Symbiont Jointly Control Gut Microbiota during Complete Metamorphosis

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The majority of animals are holometabolous insects and change dramatically through development. They undergo a dramatic transformation from a larval stage, adapted to feed, to an adult separated by a pupal stage. During this pupal stage the majority of the organs are renewed including the gut. This creates a risky situation that we study here: when the gut is renewed insects risk losing beneficial microbiota while simultaneously being at risk of opportunistic infection. Here, by manipulating host and symbiont we show how host and symbiont succeed in jointly controlling opportunistic pathogens. If one or both of the partners are compromised, opportunistic pathogens dominate the gut microbiota resulting in increased mortality. These findings may be broadly applicable to insects with complete metamorphosis, including many disease vectors.

Vyšlo v časopise: Host and Symbiont Jointly Control Gut Microbiota during Complete Metamorphosis. PLoS Pathog 11(11): e32767. doi:10.1371/journal.ppat.1005246
Kategorie: Research Article
prolekare.web.journal.doi_sk: https://doi.org/10.1371/journal.ppat.1005246

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