Current Trends in Using PET Radiopharmaceuticals for Diagnostics in Oncology

Česká verzia

Authors: J. Adam ^1,2; J. Kadeřávek ²; F. Kužel ²; J. Vašina ³; Z. Řehák ^1,3
Authors place of work: Regionální centrum aplikované molekulární onkologie, Masarykův onkologický ústav, Brno ¹; ÚJV Řež, a. s., Husinec‑ Řež ²; Oddělení nukleární medicíny, Masarykův onkologický ústav, Brno ³
Published in the journal: Klin Onkol 2014; 27(Supplementum): 129-136

Summary

Nuclear medicine is an important field of modern medicine, particularly thanks to its role in in vivo imaging of important processes in human organism. This is possible thanks to the use of radiopharmaceuticals, specific substances labeled by radioactive nuclide, its distribution in the body can be visualized by specialized scanners and, based on the knowledge of physiological patterns, diagnosis can be determined. Positron emission tomography (PET) is a modern and in many ways indispensable method of nuclear medicine. The spectrum of radiopharmaceuticals available in recent years is broadening thanks to a coordinated effort of manufacturers of synthesis equipment, chemists and potential users – physicians. This review focuses on the development in the PET radiopharmaceutical field in the last five years, with an emphasis on oncological applications of PET.

Key words:
nuclear medicine – positron-emission tomography – radiopharmaceuticals – gallium-68 – carbon-11 – fluorine-18 – zirconium-89

This work was supported by the European Regional Development Fund and the State Budget of the Czech Republic (RECAMO, CZ.1.05/2.1.00/03.0101) and by MH CZ – DRO (MMCI, 00209805).

The authors declare they have no potential conflicts of interest concerning drugs, products, or services used in the study.

The Editorial Board declares that the manuscript met the ICMJE “uniform requirements” for biomedical papers.

Submitted:
3. 2. 2014

Accepted:
3. 4. 2014

Zdroje

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