Global Genetic Variations Predict Brain Response to Faces

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We measured brain response to facial expressions in a large sample of typically developing adolescents (n = 1,620) and assessed “heritability” of the response using common genetic variations across the genome. In a subset of brain regions, we explained 40–50% of phenotypic variance by genetic variance. These brain regions appear to differ from the rest of the face network in the degree of inter-individual variations in their functional connectivity. We propose that these regions, including the prefrontal and premotor cortex, represent “Optional” part of the network co-opted by its “Obligatory” members, including the posterior part of the superior temporal sulcus, fusiform face area and the lateral occipital cortex, concerned with processing complex visual stimuli.

Vyšlo v časopise: Global Genetic Variations Predict Brain Response to Faces. PLoS Genet 10(8): e32767. doi:10.1371/journal.pgen.1004523
Kategorie: Research Article
prolekare.web.journal.doi_sk: https://doi.org/10.1371/journal.pgen.1004523

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