Reproductive Mode and the Evolution of Genome Size and Structure in Nematodes

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Closely related species can vary widely in genome size, yet the genetic and evolutionary forces responsible for these differences are poorly understood. Among Caenorhabditis nematodes, self-fertilizing species have genomes 20–40% smaller than outcrossing species. Constructing a high quality de novo genome assembly in C. remanei, we find that this outcrossing species has many more protein coding genes than the self-fertilizing Caenorhabditis. Intergenic spaces are larger on the X chromosome and smaller on autosomes for both selfing and outcrossing Caenorhabditis, but protein-coding genes are larger on the X chromosome in the self-fertile C. briggsae and C. elegans and larger on autosomes in the outcrossing C. remanei. This contrasting pattern of contracting genomes and expanding genes is likely mediated by changes in the balance between genetic drift and natural selection accompanying the transition to self-fertilization.

Vyšlo v časopise: Reproductive Mode and the Evolution of Genome Size and Structure in Nematodes. PLoS Genet 11(6): e32767. doi:10.1371/journal.pgen.1005323
Kategorie: Research Article
prolekare.web.journal.doi_sk: https://doi.org/10.1371/journal.pgen.1005323

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