Inferring Influenza Infection Attack Rate from Seroprevalence Data

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Seroprevalence studies have been regarded as the most practical method for accurately estimating the number of infections in influenza epidemics and pandemics. However, methods for inferring the number of infections from seroprevalence data in previous studies have mostly been based on conventional practice instead of standardized criteria. Specifically, there are no systematic criteria on how to select the seropositivity threshold and adjust for the proportion of infections that become seropositive. Here, we showed that under the conventional criteria, the number of 2009 pandemic influenza A/H1N1 infections had been substantially underestimated in Hong Kong as well as other countries, mostly due to overestimation of the proportion of infections that became seropositive. Our results highlighted the need to reexamine the widely accepted practice in interpreting seroprevalence data, especially in the context of pandemics when little is known but robust and comparable estimates of the number of infections and severity are most needed for informing situational awareness and guiding control policies.

Vyšlo v časopise: Inferring Influenza Infection Attack Rate from Seroprevalence Data. PLoS Pathog 10(4): e32767. doi:10.1371/journal.ppat.1004054
Kategorie: Research Article
prolekare.web.journal.doi_sk: https://doi.org/10.1371/journal.ppat.1004054

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1. Van KerkhoveMD, AsikainenT, BeckerNG, BjorgeS, DesenclosJ-C, et al. (2010) Studies Needed to Address Public Health Challenges of the 2009 H1N1 Influenza Pandemic: Insights from Modeling. PLoS Med 7: e1000275.

2. LipsitchM, FinelliL, HeffernanRT, LeungGM, ReddSC, et al. (2011) Improving the evidence base for decision making during a pandemic: the example of 2009 influenza A/H1N1. Biosecurity and bioterrorism : biodefense strategy, practice, and science 9: 89–115.

3. Fineberg HV, Aavitsland P, Aditama T, Bino S, Carmo EH, et al.. (2011) Implementation of the international health regulations (2005): report of the Review Committee on the Functioning of the International Health Regulations (2005) and on Pandemic Influenza A(H1N1) 2009. Geneva: World Health Organization.

4. BrobergE, NicollA, Amato-GauciA (2011) Seroprevalence to influenza A(H1N1) 2009 virus–where are we? Clin Vaccine Immunol 18: 1205–1212.

5. Van KerkhoveMD, HirveS, KoukounariA, MountsAW (2013) Estimating age-specific cumulative incidence for the 2009 influenza pandemic: a meta-analysis of A(H1N1)pdm09 serological studies from 19 countries. Influenza and Other Respiratory Viruses 7: 872–886.

6. BandaranayakeD, HuangQS, BissieloA, WoodT, MackerethG, et al. (2010) Risk Factors and Immunity in a Nationally Representative Population following the 2009 Influenza A(H1N1) Pandemic. PLoS ONE 5: e13211.

7. ChenMI, BarrIG, KohGCH, LeeVJ, LeeCPS, et al. (2010) Serological Response in RT-PCR Confirmed H1N1-2009 Influenza A by Hemagglutination Inhibition and Virus Neutralization Assays: An Observational Study. PLoS ONE 5: e12474.

8. DudarevaS, SchweigerB, ThammM, HöhleM, StarkK, et al. (2011) Prevalence of Antibodies to 2009 Pandemic Influenza A (H1N1) Virus in German Adult Population in Pre- and Post-Pandemic Period. PLoS ONE 6: e21340.

9. McVernon JLK, NolanT, OwenR, IrvingD, CapperH, et al. (2010) Seroprevalence of 2009 pandemic influenza A(H1N1) virus in Australian blood donors, October - December, 2009. Eurosurveillance 15: pii = 19678.

10. MillerE, HoschlerK, HardelidP, StanfordE, AndrewsN, et al. (2010) Incidence of 2009 pandemic influenza A H1N1 infection in England: a cross-sectional serological study. The Lancet 375: 1100–1108.

11. WuJT, MaESK, LeeCK, ChuDKW, HoP-L, et al. (2010) The Infection Attack Rate and Severity of 2009 Pandemic H1N1 Influenza in Hong Kong. Clinical Infectious Diseases 51: 1184–1191.

12. BaguelinM, HoschlerK, StanfordE, WaightP, HardelidP, et al. (2011) Age-Specific Incidence of A/H1N1 2009 Influenza Infection in England from Sequential Antibody Prevalence Data Using Likelihood-Based Estimation. PLoS ONE 6: e17074.

13. WuJT, HoA, MaESK, LeeCK, ChuDKW, et al. (2011) Estimating Infection Attack Rates and Severity in Real Time during an Influenza Pandemic: Analysis of Serial Cross-Sectional Serologic Surveillance Data. PLoS Med 8: e1001103.

14. CoxCM, GoodinK, FisherE, DawoodFS, HamiltonJJ, et al. (2011) Prevalence of 2009 pandemic influenza A (H1N1) virus antibodies, Tampa Bay Florida–November-December, 2009. PLoS ONE 6: e29301.

15. ReedC, KatzJM, HancockK, BalishA, FryAM, et al. (2012) Prevalence of Seropositivity to Pandemic Influenza A/H1N1 Virus in the United States following the 2009 Pandemic. PLoS ONE 7: e48187.

16. Hens N, Shkedy Z, Aerts M, Faes C, Van Damme P, et al.. (2012) Modeling Infectious Disease Parameters Based on Serological and Social Contact Data: Springer. 298 p.

17. SteensA, WaaijenborgS, TeunisPFM, ReimerinkJHJ, MeijerA, et al. (2011) Age-Dependent Patterns of Infection and Severity Explaining the Low Impact of 2009 Influenza A (H1N1): Evidence From Serial Serologic Surveys in the Netherlands. American Journal of Epidemiology 174: 1307–1315.

18. HardelidP, WilliamsD, DezadeuxC, TookeyPA, PeckhamCS, et al. (2008) Analysis of rubella antibody distribution from newborn dried blood spots using finite mixture models. Epidemiology & Infection 136: 1698–1706.

19. VyseAJ, AndrewsNJ, HeskethLM, PebodyR (2007) The burden of parvovirus B19 infection in women of childbearing age in England and Wales. Epidemiology & Infection 135: 1354–1362.

20. CowlingBJ, LauMSY, HoL-M, ChuangS-K, TsangT, et al. (2010) The Effective Reproduction Number of Pandemic Influenza: Prospective Estimation. Epidemiology 21: 842–846 810.1097/EDE.1090b1013e3181f20977.

21. WuJT, CowlingBJ, LauEHY, IpDKM, HoL-M, et al. (2010) School Closure and Mitigation of Pandemic (H1N1) 2009, Hong Kong. Emerging Infectious Diseases 16: 538–541.

22. WuJT, MaESK, LeeCK, ChuDKW, HoPL, et al. (2010) The infection attack rate and severity of 2009 pandemic influenza (H1N1) in Hong Kong. Clinical Infectious Diseases 51: 1184–1191.

23. HungIFN, ToKKW, LeeC-K, LinC-K, ChanJFW, et al. (2010) Effect of Clinical and Virological Parameters on the Level of Neutralizing Antibody against Pandemic Influenza A Virus H1N1 2009. Clinical Infectious Diseases 51: 274–279.

24. VeguillaV, HancockK, SchifferJ, GargiulloP, LuX, et al. (2011) Sensitivity and Specificity of Serologic Assays for Detection of Human Infection with 2009 Pandemic H1N1 Virus in U.S. Populations. Journal of Clinical Microbiology 49: 2210–2215.

25. CowlingBJ, ChanKH, FangVJ, LauLLH, SoHC, et al. (2010) Comparative Epidemiology of Pandemic and Seasonal Influenza A in Households. New England Journal of Medicine 362: 2175–2184.

26. MossongJ, HensN, JitM, BeutelsP, AuranenK, et al. (2008) Social Contacts and Mixing Patterns Relevant to the Spread of Infectious Diseases. PLoS Med 5: e74.

27. BoëlleP-Y, AnsartS, CoriA, ValleronA-J (2011) Transmission parameters of the A/H1N1 (2009) influenza virus pandemic: a review. Influenza and Other Respiratory Viruses 5: 306–316.

28. CauchemezS, DonnellyCA, ReedC, GhaniAC, FraserC, et al. (2009) Household Transmission of 2009 Pandemic Influenza A (H1N1) Virus in the United States. New England Journal of Medicine 361: 2619–2627.

29. CauchemezS, BhattaraiA, MarchbanksTL, FaganRP, OstroffS, et al. (2011) Role of social networks in shaping disease transmission during a community outbreak of 2009 H1N1 pandemic influenza. Proceedings of the National Academy of Sciences 108: 2825–2830.

30. HardelidP, AndrewsN, HoschlerK, StanfordE, BaguelinM, et al. (2010) Assessment of baseline age-specific antibody prevalence and incidence of infection to novel influenza A/H1N1. Health Technology Assessment 14: 115–192.

31. PapenburgJ, BazM, HamelinM-È, RhéaumeC, CarbonneauJ, et al. (2011) Evaluation of Serological Diagnostic Methods for the 2009 Pandemic Influenza A (H1N1) Virus. Clinical and Vaccine Immunology 18: 520–522.

32. WoodJM, Gaines-DasRE, TaylorJ, ChakravertyP (1994) Comparison of influenza serological techniques by international collaborative study. Vaccine 12: 167–174.

33. MakGC, ChoyPWW, LeeWY, WongAH, NgKC, et al. (2010) Sero-immunity and serologic response to pandemic influenza A (H1N1) 2009 virus in Hong Kong. Journal of Medical Virology 82: 1809–1815.

34. TuW, MaoH, ZhengJ, LiuY, ChiuSS, et al. (2010) Cytotoxic T lymphocytes established by seasonal human influenza cross-react against 2009 pandemic H1N1 influenza virus. Journal of virology 84: 6527–6535.

35. TangJW, NgaiKL, LamWY, ChanPK (2008) Seasonality of influenza A(H3N2) virus: a Hong Kong perspective (1997–2006). PLoS ONE 3: e2768.

36. CauchemezS, HorbyP, FoxA, Mai leQ, Thanh leT, et al. (2012) Influenza infection rates, measurement errors and the interpretation of paired serology. PLoS Pathog 8: e1003061.

37. BirrellPJ, KetsetzisG, GayNJ, CooperBS, PresanisAM, et al. (2011) Bayesian modeling to unmask and predict influenza A/H1N1pdm dynamics in London. Proceedings of the National Academy of Sciences 108: 18238–18243.

38. XieX, LuSQ, ChengJQ, ChengXW, XuZH, et al. (2012) Estimate of 2009 H1N1 influenza cases in Shenzhen–the biggest migratory city in China. Epidemiol Infect 140: 788–797.