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SKN-1/Nrf, A New Unfolded Protein Response Factor?


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Vyšlo v časopise: SKN-1/Nrf, A New Unfolded Protein Response Factor?. PLoS Genet 9(9): e32767. doi:10.1371/journal.pgen.1003827
Kategorie: Perspective
prolekare.web.journal.doi_sk: https://doi.org/10.1371/journal.pgen.1003827

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Zdroje

1. Glover-CutterKM, LinS, BlackwellTK (2013) Integration of the unfolded protein and oxidative stress responses through SNK-1/Nrf. PLoS Genet 9: e1003701 doi:10.1371/journal.pgen.1003701

2. HigaA, ChevetE (2012) Redox signaling loops in the unfolded protein response. Cell Signal 24: 1548–1555.

3. CullinanSB, DiehlJA (2006) Coordination of ER and oxidative stress signaling: the PERK/Nrf2 signaling pathway. Int J Biochem Cell Biol 38: 317–332.

4. BhandaryB, MarahattaA, KimHR, ChaeHJ (2012) An involvement of oxidative stress in endoplasmic reticulum stress and its associated diseases. Int J Mol Sci 14: 434–456.

5. Robida-StubbsS, Glover-CutterK, LammingDW, MizunumaM, NarasimhanSD, et al. (2012) TOR signaling and rapamycin influence longevity by regulating SKN-1/Nrf and DAF-16/FoxO. Cell Metab 15: 713–724.

6. TulletJMA, HertweckM, AnJH, BakerJ, HwangJY, et al. (2008) Direct inhibition of the longevity-promoting factor SKN-1 by insulin-like signaling in C. elegans. Cell 132: 1025–1038.

7. SykiotisG, BohmannD (2010) Stress-activated cap'n'collar transcription factors in aging and human disease. Sci Signal 3: re3.

8. SykiotisGP, BohmannD (2008) Keap1/Nrf2 signaling regulates oxidative stress tolerance and lifespan in Drosophila. Dev Cell 14: 76–85.

9. MalhotraJD, KaufmanRJ (2007) Endoplasmic reticulum stress and oxidative stress: a vicious cycle or a double-edged sword? Antioxid Redox Signal 9: 2277–2293.

10. InoueH, HisamotoN, AnJH, OliveiraRP, NishidaE, et al. (2005) The C. elegans p38 MAPK pathway regulates nuclear localization of the transcription factor SKN-1 in oxidative stress response. Genes Dev 19: 2278–2283.

11. LeeCS, HoDV, ChanJY (2013) Nuclear factor-erythroid 2-related factor 1 regulates expression of proteasome genes in hepatocytes and protects against endoplasmic reticulum stress and steatosis in mice. FEBS J 280: 3609–20 doi:10.1111/febs.12350

12. CullinanSB, ZhangD, HanninkM, ArvisaisE, KaufmanRJ, et al. (2003) Nrf2 is a direct PERK substrate and effector of PERK-dependent cell survival. Mol Cell Biol 23: 7198–7209.

13. CullinanSB, DiehlJA (2004) PERK-dependent activation of Nrf2 contributes to redox homeostasis and cell survival following endoplasmic reticulum stress. J Biol Chem 279: 20108–20117.

14. ZhangY, KobayashiA, YamamotoM, HayesJD (2009) The Nrf3 transcription factor is a membrane-bound glycoprotein targeted to the endoplasmic reticulum through its N-terminal homology box 1 sequence. J Biol Chem 284: 3195–3210.

15. WangW, ChanJY (2006) Nrf1 is targeted to the endoplasmic reticulum membrane by an N-terminal transmembrane domain. Inhibition of nuclear translocation and transacting function. J Biol Chem 281: 19676–19687.

16. ZhangY, CrouchDH, YamamotoM, HayesJD (2006) Negative regulation of the Nrf1 transcription factor by its N-terminal domain is independent of Keap1: Nrf1, but not Nrf2, is targeted to the endoplasmic reticulum. Biochem J 399: 373–385.

17. LeungCK, EmpinadoH, ChoeKP (2012) Depletion of a nucleolar protein activates xenobiotic detoxification genes in Caenorhabditis elegans via Nrf/SKN-1 and p53/CEP-1. Free Radic Biol Med 52: 937–950.

18. LiX, MatilainenO, JinC, Glover-CutterKM, HolmbergCI, et al. (2011) Specific SKN-1/Nrf stress responses to perturbations in translation elongation and proteasome activity. PLoS Genet 7: e1002119 doi:10.1371/journal.pgen.1002119

19. WangJ, Robida-StubbsS, TulletJM, RualJF, VidalM, et al. (2010) RNAi screening implicates a SKN-1-dependent transcriptional response in stress resistance and longevity deriving from translation inhibition. PLoS Genet 6: e1001048 doi:10.1371/journal.pgen.1001048

Štítky
Genetika Reprodukčná medicína

Článok vyšiel v časopise

PLOS Genetics


2013 Číslo 9
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