Palaeosymbiosis Revealed by Genomic Fossils of in a Strongyloidean Nematode

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Bovine lungworms are economically important nematode parasites of cattle. We have sequenced the genome of the bovine lungworm to provide information for drug and vaccine discovery. Within the lungworm genome we found extensive evidence of an ancient association between the lungworm and a bacterium called Wolbachia. The lungworm Wolbachia is now a “fossil” in the genome, but tells of an ancient infection. Association between lungworms, and related nematode worms, and Wolbachia was not known previously. We have used the lungworm Wolbachia sequence to explore the history of nematode-Wolbachia interactions, particularly the jumping of these symbionts between arthropods and nematodes.

Vyšlo v časopise: Palaeosymbiosis Revealed by Genomic Fossils of in a Strongyloidean Nematode. PLoS Genet 10(6): e32767. doi:10.1371/journal.pgen.1004397
Kategorie: Research Article
prolekare.web.journal.doi_sk: https://doi.org/10.1371/journal.pgen.1004397

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