Mutagenesis by AID: Being in the Right Place at the Right Time
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Vyšlo v časopise:
Mutagenesis by AID: Being in the Right Place at the Right Time. PLoS Genet 11(9): e32767. doi:10.1371/journal.pgen.1005489
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Perspective
prolekare.web.journal.doi_sk:
https://doi.org/10.1371/journal.pgen.1005489
Souhrn
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Zdroje
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4. Alexandrov LB, Nik-Zainal S, Wedge DC, Aparicio SAJR, Behjati S, Biankin AV, et al. Signatures of mutational processes in human cancer. Nature. 2013;500:415–421. doi: 10.1038/nature12477 23945592
5. Pettersen HS, Galashevskaya A, Doseth B, Sousa MML, Sarno A, Visnes T, et al. AID expression in B-cell lymphomas causes accumulation of genomic uracil and a distinct AID mutational signature. DNA Repair (Amst). 2015;25:60–71.
6. Orthwein A, Di Noia JM. Activation induced deaminase: how much and where? Seminars in Immunology. 2012;24:246–254. doi: 10.1016/j.smim.2012.05.001 22687198
7. Faili A, Aoufouchi S, Guéranger Q, Zober C, Léon A, Bertocci B, et al. AID-dependent somatic hypermutation occurs as a DNA single-strand event in the BL2 cell line. Nat Immunol. 2002;3: 815–821. 12145648
8. Sharbeen G, Yee CWY, Smith AL, Jolly CJ. Ectopic restriction of DNA repair reveals that UNG2 excises AID-induced uracils predominantly or exclusively during G1 phase. J Exp Med. 2012;209: 965–974. doi: 10.1084/jem.20112379 22529268
9. Peña-Diaz J, Jiricny J. Mammalian mismatch repair: error-free or error-prone? Trends Biochem Sci. 2012;37: 206–214. doi: 10.1016/j.tibs.2012.03.001 22475811
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Štítky
Genetika Reprodukčná medicínaČlánok vyšiel v časopise
PLOS Genetics
2015 Číslo 9
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