Inter-Seasonal Influenza is Characterized by Extended Virus Transmission and Persistence

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Human influenza virus commonly causes disease in the winter months of temperate countries, but exhibits more complex patterns in tropical localities. Most studies of this complex seasonality have only considered viruses sampled within the “normal” influenza season. To help reveal the drivers of influenza seasonality we utilized viruses sampled outside of the normal influenza season, focusing on Australia which is characterized by a wide range of climates. Using a phylogenetic approach we revealed more complex patterns of influenza transmission than previously anticipated, particularly that the virus is able to transmit for extended periods and even persist locally within Australia throughout the virus “off-season”. In addition, we found that inter-seasonal influenza was more frequent in tropical and sub-tropical than temperate regions, adding weight to theories that climate likely plays an important role in influenza seasonality.

Vyšlo v časopise: Inter-Seasonal Influenza is Characterized by Extended Virus Transmission and Persistence. PLoS Pathog 11(6): e32767. doi:10.1371/journal.ppat.1004991
Kategorie: Research Article
prolekare.web.journal.doi_sk: https://doi.org/10.1371/journal.ppat.1004991

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