The Drosophila Gene Interacts Genetically with and Shows Female-Specific Effects of Divergence

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Animals need to make gametes–sperm or eggs–in order to reproduce. Gametes are produced from a specialized tissue called the germline that is found within the testes or ovaries. These organs contain a small population of stem cells that are able to both self-renew and differentiate to generate gametes and are thus essential for maintaining gamete production throughout the reproductive lifespan of most animals. Surprisingly, some of the genes that control this process evolve rapidly between Drosophila species. We find for a key germline stem cell regulatory gene, bag of marbles (bam), that its rapid evolution affects only female but not male functions. We further report that the endosymbiont bacterium Wolbachia that infects insects and other species interacts with bam and may be contributing to the wider pattern of rapid evolution of germline stem cell regulatory genes.

Vyšlo v časopise: The Drosophila Gene Interacts Genetically with and Shows Female-Specific Effects of Divergence. PLoS Genet 11(8): e32767. doi:10.1371/journal.pgen.1005453
Kategorie: Research Article
prolekare.web.journal.doi_sk: https://doi.org/10.1371/journal.pgen.1005453

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