DCAF26, an Adaptor Protein of Cul4-Based E3, Is Essential for DNA Methylation in

1. O'ConnellBC

HarperJW

2007 Ubiquitin proteasome system (UPS): what can chromatin do for you? Curr Opin Cell Biol 19 206 214

2. HigaLA

ZhangH

2007 Stealing the spotlight: CUL4-DDB1 ubiquitin ligase docks WD40-repeat proteins to destroy. Cell Div 2 5

3. LeeJ

ZhouP

2007 DCAFs, the missing link of the CUL4-DDB1 ubiquitin ligase. Mol Cell 26 775 780

4. AngersS

LiT

YiX

MacCossMJ

MoonRT

2006 Molecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machinery. Nature 443 590 593

5. PetroskiMD

DeshaiesRJ

2005 Function and regulation of cullin-RING ubiquitin ligases. Nat Rev Mol Cell Biol 6 9 20

6. GroismanR

KuraokaI

ChevallierO

GayeN

MagnaldoT

2006 CSA-dependent degradation of CSB by the ubiquitin-proteasome pathway establishes a link between complementation factors of the Cockayne syndrome. Genes Dev 20 1429 1434

7. LiuC

PoiteleaM

WatsonA

YoshidaSH

ShimodaC

2005 Transactivation of Schizosaccharomyces pombe cdt2+ stimulates a Pcu4-Ddb1-CSN ubiquitin ligase. Embo J 24 3940 3951

8. LiT

ChenX

GarbuttKC

ZhouP

ZhengN

2006 Structure of DDB1 in complex with a paramyxovirus V protein: viral hijack of a propeller cluster in ubiquitin ligase. Cell 124 105 117

9. FukumotoY

DohmaeN

HanaokaF

2008 Schizosaccharomyces pombe Ddb1 recruits substrate-specific adaptor proteins through a novel protein motif, the DDB-box. Mol Cell Biol 28 6746 6756

10. DouY

MilneTA

TackettAJ

SmithER

FukudaA

2005 Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF. Cell 121 873 885

11. RuthenburgAJ

WangW

GrayboschDM

LiH

AllisCD

2006 Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex. Nat Struct Mol Biol 13 704 712

12. WysockaJ

SwigutT

MilneTA

DouY

ZhangX

2005 WDR5 associates with histone H3 methylated at K4 and is essential for H3 K4 methylation and vertebrate development. Cell 121 859 872

13. HigaLA

WuM

YeT

KobayashiR

SunH

2006 CUL4-DDB1 ubiquitin ligase interacts with multiple WD40-repeat proteins and regulates histone methylation. Nat Cell Biol 8 1277 1283

14. JiaS

KobayashiR

GrewalSI

2005 Ubiquitin ligase component Cul4 associates with Clr4 histone methyltransferase to assemble heterochromatin. Nat Cell Biol 7 1007 1013

15. HongEJ

VillenJ

GeraceEL

GygiSP

MoazedD

2005 A cullin E3 ubiquitin ligase complex associates with Rik1 and the Clr4 histone H3-K9 methyltransferase and is required for RNAi-mediated heterochromatin formation. RNA Biol 2 106 111

16. HornPJ

BastieJN

PetersonCL

2005 A Rik1-associated, cullin-dependent E3 ubiquitin ligase is essential for heterochromatin formation. Genes Dev 19 1705 1714

17. LiF

GotoDB

ZaratieguiM

TangX

MartienssenR

2005 Two novel proteins, dos1 and dos2, interact with rik1 to regulate heterochromatic RNA interference and histone modification. Curr Biol 15 1448 1457

18. ThonG

HansenKR

AltesSP

SidhuD

SinghG

2005 The Clr7 and Clr8 directionality factors and the Pcu4 cullin mediate heterochromatin formation in the fission yeast Schizosaccharomyces pombe. Genetics 171 1583 1595

19. ZhaoY

ShenY

YangS

WangJ

HuQ

2010 Ubiquitin ligase components Cullin4 and DDB1 are essential for DNA methylation in Neurospora crassa. J Biol Chem 285 4355 4365

20. LeeJH

TerzaghiW

GusmaroliG

CharronJB

YoonHJ

2008 Characterization of Arabidopsis and rice DWD proteins and their roles as substrate receptors for CUL4-RING E3 ubiquitin ligases. Plant Cell 20 152 167

21. AronsonBD

JohnsonKA

LorosJJ

DunlapJC

1994 Negative feedback defining a circadian clock: autoregulation of the clock gene frequency. Science 263 1578 1584

22. HeQ

ChengP

HeQ

LiuY

2005 The COP9 signalosome regulates the Neurospora circadian clock by controlling the stability of the SCFFWD-1 complex. Genes Dev 19 1518 1531

23. TamaruH

SelkerEU

2001 A histone H3 methyltransferase controls DNA methylation in Neurospora crassa. Nature 414 277 283

24. TamaruH

ZhangX

McMillenD

SinghPB

NakayamaJ

2003 Trimethylated lysine 9 of histone H3 is a mark for DNA methylation in Neurospora crassa. Nat Genet 34 75 79

25. SugasawaK

OkudaY

SaijoM

NishiR

MatsudaN

2005 UV-induced ubiquitylation of XPC protein mediated by UV-DDB-ubiquitin ligase complex. Cell 121 387 400

26. LewisZA

AdhvaryuKK

HondaS

ShiverAL

SelkerEU

2010 Identification of DIM-7, a protein required to target the DIM-5 H3 methyltransferase to chromatin. Proc Natl Acad Sci U S A 107 8310 8315

27. FreitagM

HickeyPC

KhlafallahTK

ReadND

SelkerEU

2004 HP1 is essential for DNA methylation in neurospora. Mol Cell 13 427 434

28. KouzminovaE

SelkerEU

2001 dim-2 encodes a DNA methyltransferase responsible for all known cytosine methylation in Neurospora. Embo J 20 4309 4323

29. JinJ

AriasEE

ChenJ

HarperJW

WalterJC

2006 A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1. Mol Cell 23 709 721

30. HeYJ

McCallCM

HuJ

ZengY

XiongY

2006 DDB1 functions as a linker to recruit receptor WD40 proteins to CUL4-ROC1 ubiquitin ligases. Genes Dev 20 2949 2954

31. WangH

ZhaiL

XuJ

JooHY

JacksonS

2006 Histone H3 and H4 ubiquitylation by the CUL4-DDB-ROC1 ubiquitin ligase facilitates cellular response to DNA damage. Mol Cell 22 383 394

32. ChengP

YangY

HeintzenC

LiuY

2001 Coiled-coil domain-mediated FRQ-FRQ interaction is essential for its circadian clock function in Neurospora. Embo J 20 101 108

33. GarceauNY

LiuY

LorosJJ

DunlapJC

1997 Alternative initiation of translation and time-specific phosphorylation yield multiple forms of the essential clock protein FREQUENCY. Cell 89 469 476

34. BraunsteinM

RoseAB

HolmesSG

AllisCD

BroachJR

1993 Transcriptional silencing in yeast is associated with reduced nucleosome acetylation. Genes Dev 7 592 604