Interaction between Conjugative and Retrotransposable Elements in Horizontal Gene Transfer

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Mobile genetic elements are segments of DNA that capable of “jumping” within a single DNA molecule, between chromosomes or even between cells. They usually encode the enzymes that mediate their own transfer and integration into new DNA locus. The transfer of mobile genetic elements between cells is known as horizontal gene transfer and it is common in Bacteria. Conjugative plasmids are major means to horizontal gene transfer often carrying a variety of putative virulence factors and antibiotics resistance determinants among and within bacterial species. Thus, conjugative plasmids play a crucial role in the plasticity of the genome, allowing bacteria to adjust readily to new environments. Other mobile elements, such as mobile group II introns, were found to be associated with conjugative plasmids. Here, we demonstrated that mobile group II intron and conjugative plasmid interact promoting gene transfer, and potentially providing a mutual benefit to each other.

Vyšlo v časopise: Interaction between Conjugative and Retrotransposable Elements in Horizontal Gene Transfer. PLoS Genet 10(12): e32767. doi:10.1371/journal.pgen.1004853
Kategorie: Research Article
prolekare.web.journal.doi_sk: https://doi.org/10.1371/journal.pgen.1004853

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