Resistance to Gray Leaf Spot of Maize: Genetic Architecture and Mechanisms Elucidated through Nested Association Mapping and Near-Isogenic Line Analysis

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Gray leaf spot (GLS), a necrotrophic, foliar fungal disease of maize, contributes to maize yield losses worldwide. We identified and characterized regions of the maize genome that confer resistance to GLS and gained insight into the mechanisms associated with these quantitative trait loci (QTL). We provide evidence for structural and detoxification-related mechanisms underlying quantitative resistance. The distance between major veins of the maize leaf was positively correlated with the quantity of fungal conidiophores (reproductive structures) produced. Four of the GLS QTL were associated with inter-vein distance, and co-localization was confirmed for one of these QTL in near-isogenic lines. In addition, up-regulation of a putative detoxification-related flavin-monooxygenase gene was correlated with a fine-mapped QTL. Plant breeding decisions regarding development and deployment of disease resistance traits can be improved with better understanding of the mechanisms underlying quantitative disease resistance.

Vyšlo v časopise: Resistance to Gray Leaf Spot of Maize: Genetic Architecture and Mechanisms Elucidated through Nested Association Mapping and Near-Isogenic Line Analysis. PLoS Genet 11(3): e32767. doi:10.1371/journal.pgen.1005045
Kategorie: Research Article
prolekare.web.journal.doi_sk: https://doi.org/10.1371/journal.pgen.1005045

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