Adherence to iron-folic acid supplement and associated factors among antenatal care attending pregnant mothers in governmental health institutions of Adwa town, Tigray, Ethiopia: Cross-sectional study

English version

Autoři: Tsgehana Gebregyorgis Gebremichael ^aff001; Tsehaynesh Gidey Welesamuel ^aff002
Působiště autorů: Department of Human Nutrition, Axum University Specialized and Compressive Hospital,Axum University,Axum,Ethiopia ^aff001; Department of Public Health, Axum University Specialized and Compressive Hospital,Axum University,Axum,Ethiopia ^aff002
Vyšlo v časopise: PLoS ONE 15(1)
Kategorie: Research Article
prolekare.web.journal.doi_sk: https://doi.org/10.1371/journal.pone.0227090

Souhrn

Background

Iron-folic acid supplementation during pregnancy is among the very effective interventions to prevent iron deficiency anemia, low birth weight, and prematurity. There is a need of having recent studies on adherence to the supplement that consider the very recent interventions targeted to scale up the use of iron–folic acid (IFA) supplement. Therefore we sought to assess adherence to IFA supplement and its associated factors among antenatal care attending pregnant mothers in governmental health institutions of Adwa town.

Methods

Institution-based cross-sectional study was conducted among 629 antenatal care attending pregnant mothers. Systematic random sampling method was used to select the study subjects. Data were collected through face-to-face interview and chart-review. Bivariable and multivariable binary logistic regression was computed. Variables with P-value <0.05 were considered statistically significant at 95% confidence interval (CI).

Result

Only 40.9% (95%CI: 37.0%- 44.7%) of participants were adherent (took four or more tablets per week). Women in the age group of 25–29 years [AOR: 2.22(1.21–4.07)] had increased odds of adherence as compared to those in the age group ≥ 35 years. Women who received nutrition counseling [AOR: 4.12(2.12–8.03)] and partner support [AOR: 2.23 (1.42–3.49)] had increased odds of adherence as compared to those who didn’t receive nutrition counseling and partner support respectively. Similarly, women who had satisfactory knowledge on IFA supplement (AOR: 2.16(1.37–3.40)) had increased odds of adherence as compared to those who didn’t have satisfactory knowledge on IFA supplement.

Conclusion

Adherence to the supplement was low. Efforts shall be done to improve awareness of pregnant mothers about IFA supplement through targeted nutrition counseling that includes the engagement of a partner.

Klíčová slova:

Pregnancy – Nutrition – Age groups – Adverse reactions – Parenting behavior – Antenatal care – Iron deficiency anemia – anémia

Zdroje

1. Christian P, Mullany LC, Hurley KM, Katz J, Black RE. Nutrition and maternal,neonatal, and child health. Semin Perinatol. 2015;39(5):361–72. doi: 10.1053/j.semperi.2015.06.009 26166560

2. Organization WH. Essential nutrition actions: improving maternal, newborn,infant and young child health and nutrition. Geneva: Organization WH;2013

3. Marti-carvaja A.L,Pena-marti G,Comunian G,Munoz S: Prevalence of anemia during pregnancy: Results of Valencia (Venezuela) anemia during pregnancy study, 2002.

4. Targets WGN. 2025: Anaemia policy brief. Geneva: World Health Organization. 2014.

5. McLean E, Cogswell M, Egli I, Wojdyla D, De Benoist B. Worldwide prevalence of anaemia, WHO vitamin and mineral nutrition information system, 1993–2005. Public health nutrition. 2009;12(4):444–54. doi: 10.1017/S1368980008002401 18498676

6. Molloy AM, Kirke PN, Brody LC, Scott JM, Mills JL. Effects of folate and vitamin B12 deficiencies during pregnancy on fetal, infant, and child development. Food and nutrition bulletin. 2008;29(2_suppl1):S101–S11.

7. Imdad A, Bhutta ZA. Routine iron/folate supplementation during pregnancy: effect on maternal anaemia and birth outcomes. Paediatric and perinatal epidemiology. 2012;26:168–77. doi: 10.1111/j.1365-3016.2012.01312.x 22742609

8. Rahman MM, Abe SK, Rahman MS, Kanda M, Narita S, Bilano V, et al. Maternal anemia and risk of adverse birth and health outcomes in low-and middle-income countries: systematic review and meta-analysis1,2.The American journal of clinical nutrition. 2016;103(2):495–504. doi: 10.3945/ajcn.115.107896 26739036

9. Tetanus WMİA. Integrated Management Of Pregnancy And Chıldbırth. Standards For Maternal And Neonatal Care Developed By The Department Of Making Pregnancy Safer. Geneva: World Health Organization, 2006

10. Federal Ministry of Health of Ethiopia. A a national guideline for control and prevention of micronutrient deficiencies. Addis Ababa: FMOH; 2016

11. Ethiopia national nutrition program (NNP II), Ethiopia. 2016

12. Central Statistical Agency of Ethiopia. Ethiopia Demographic and Health Survey 2016.Addis Ababa, Ethiopia, and Rockville, Maryland, USA: CSA and ICF.

13. Arega Sadore A, Abebe Gebretsadik L, Aman Hussen M. Compliance with Iron-folate supplement and associated factors among antenatal care attendant mothers in Misha District, South Ethiopia: community based cross-sectional study. Journal of environmental and public health. 2015;2015

14. Ethiopian public health instutuite.Ethiopian national micronutrient survey report.Addis Ababa;2016

15. Gebre A, Afework M, Belachew E. Assessment of factors associated with adherence to iron-folic acid supplementation among urban and rural pregnant women in North Western Zone of Tigray, Ethiopia: comparative Study. Int J Nutr Food Sci. 2015;4(2):161–8.

16. Birhanuet al.Compliance to iron and folic acid supplementation in pregnancy, Northwest Ethiopia.BMC Research Notes.2018;11:345 doi: 10.1186/s13104-018-3433-3 29848380

17. Jasti S, Siega-Riz AM, Cogswell ME, Hartzema AG, Bentley ME. Pill count adherence to prenatal multivitamin/mineral supplement use among low-income women. The Journal of nutrition. 2005;135(5):1093–101. doi: 10.1093/jn/135.5.1093 15867287

18. Gebreamlak B, Dadi AF, Atnafu A. High adherence to Iron/folic acid supplementation during pregnancy time among antenatal and postnatal care attendant mothers in governmental health centers in Akaki Kality Sub City, Addis Ababa, Ethiopia: hierarchical negative binomial Poisson regression. PloS one. 2017;12(1):e0169415. doi: 10.1371/journal.pone.0169415 28129344

19. Tegegne M. Compliance to prenatal Iron and Folic acid supplement and associated factors among women during pregnancy in South East Ethiopia: A Cross-sectional study. Global Journal of Medical Research. 2017.

20. Getachew M, Abay M, Zelalem H, Gebremedhin T, Grum T, Bayray A. Magnitude and factors associated with adherence to Iron-folic acid supplementation among pregnant women in Eritrean refugee camps, northern Ethiopia. BMC pregnancy and childbirth. 2018;18(1):83. doi: 10.1186/s12884-018-1716-2 29621996

21. Mithra P, Unnikrishnan B, Rekha T, Nithin K, Mohan K, Kulkarni V, et al. Compliance with iron-folic acid (IFA) therapy among pregnant women in an urban area of south India. African health sciences. 2013;13(4):880–5. doi: 10.4314/ahs.v13i4.3 24940307

22. Taye B, Abeje G, Mekonen A. Factors associated with compliance of prenatal iron folate supplementation among women in Mecha district, Western Amhara: a cross-sectional study. Pan African Medical Journal. 2015;20(1).

23. Shewasinad S, Negash S. Adherence and Associated Factors of Prenatal Iron Folic Acid Supplementation among Pregnant Women Who Attend Ante Natal Care in Health Facility at Mizan-Aman Town, Bench Maji Zone, Ethiopia, 2015.(2017) Journal of Pregnancy and Child Health. J Pregnancy Child Health. 2017. doi: 10.4172/2376-127X.1000301

24. Kamau MW, Mirie W, Kimani S. Compliance with Iron and folic acid supplementation (IFAS) and associated factors among pregnant women: results from a cross-sectional study in Kiambu County, Kenya. BMC public health. 2018;18(1):580. doi: 10.1186/s12889-018-5437-2 29720135