Birth asphyxia and its associated factors among newborns in public hospital, northeast Amhara, Ethiopia
Autoři:
Abay Woday aff001; Ayesheshim Muluneh aff002; Christine St Denis aff003
Působiště autorů:
Samara University, College of Medical and Health Sciences, Department of Public Health, Afar Region, Samara, Ethiopia
aff001; College of Health Science, Amhara Region, Dessie, Ethiopia
aff002; Sickkids Hospital, Toronto, Canada
aff003
Vyšlo v časopise:
PLoS ONE 14(12)
Kategorie:
Research Article
prolekare.web.journal.doi_sk:
https://doi.org/10.1371/journal.pone.0226891
Souhrn
Background
Birth asphyxia is a leading cause of infant morbidity and mortality in developing nations, such as Ethiopia. Though Ethiopia has made considerable achievement in the reduction of under-five mortality rate, the neonatal mortality burden has not experienced the same reduction, which may be attributed to birth asphyxia. Thus, this study attempts to assess the prevalence and associated factors of birth asphyxia among newborns in public hospitals in the northeastern Amhara region, Ethiopia.
Methods
An institution-based cross-sectional study was conducted on 357 births from 1st April to 2nd May 2018. The sample size was proportionally allocated to randomly selected three public hospitals namely, Dessie referral hospital, Debre Berhan referral hospital, and Woldia general hospital. The allocation was made by taking the average number of deliveries given in each hospital six months before the data collection period. Using the delivery registration of hospitals a systematic random sampling technique was used to get all study participants. The diagnosis of birth asphyxia was confirmed based on the physician’s diagnosis of an APGAR score < 7 in the 1st and 5th minutes of birth. A pretested and structured questionnaire was used to collect data. Variables with p-values < 0.25 in the bivariable analysis were entered into a multivariable logistic regression analysis. A statistical significant level was declared at a p-value of <0.05.
Results
The prevalence of birth asphyxia was found to occur 22.6% of the time [95% CI 19.2% - 26.4%] in the first minute of birth. In the multivariable logistic regression being primipara [AOR = 3.77: 95% CI 1.86, 7.65], presented with complicated labor [AOR = 3.45: 95% CI 1.58, 7.49], premature rupture of membrane [AOR = 3.85: 95% CI 1.76, 8.44) and having blood-stained amniotic fluid at birth [AOR = 5.02: 95% CI 1.69, 14.87] were the independent predictors of birth asphyxia.
Conclusion
The study revealed that birth asphyxia is a common newborn complication in the Amhara region. Integrated mitigation measure to reduce neonatal mortality in the Amahar region should give due attention to primipara women and for these high-risk pregnancies in order for the region to achieve national and global commitment to have sustainable change in women and neonatal health.
Klíčová slova:
Neonates – Birth – Labor and delivery – Pregnancy – Asphyxia – Ethiopia – Antenatal care – Amniotic fluid
Zdroje
1. World Health Organization. Recommended definitions, terminology and format for statistical tables related to the perinatal period and use of a new certificate for cause of perinatal deaths: Modifications Recommended by FIGO as Amended October 14,1976: Acta Dbstet Oynecoi Scand, 1977, 56:247–253.
2. American academy of pediatrics. neonatal encephalopathy and neurologic outcome. 2nd edition, 2014, Washington DC. Available: www.aappublications.org/news: accessed on February 11, 2018.
3. Rainaldi MA, Perlman JM. Pathophysiology of Birth Asphyxia, New York, USA. Clin Perinatol 2016, 43(3):409–422. doi: 10.1016/j.clp.2016.04.002 27524444
4. World Health Organization. Newborns: reducing mortality, 2018. Available: https://www.who.int/news-room/fact-sheet/detail, accessed on may 2,2018.
5. Joy Lawn PM, Simon Cousens.: Africa’s newborns–counting them and making them count. Opportunities for Africa’s Newborns 2010.
6. World Health Organization. GUIDELINE ON BASIC NEWBORN RESUSCITATION, 2012. Available: https://www.who.int/maternal_child_adolescent/documents/basic_newborn_resuscitation/en, accessed on April 5,2018.
7. United Nations Children's Fund [UNICEF]. Maternal and Newborn Health Disparities in Ethiopia. COUNTRY PROFIE_ETH, 2015. Available: https://www.data.unicef.org accessed on January 03, 2018.
8. Central Statistical Authority and the DHS Program.Demographic and Health Survey: Ethiopia 2016. CSA, the DHS Program ICF: Addis Ababa, Calverton; 2017.
9. Halloran DR, McClure E, Chakraborty H, Chomba E, Wright LL, Carlo WA. Birth asphyxia survivors in a developing country. J Perinatol 2009, 29(3):243–249. doi: 10.1038/jp.2008.192 19037228
10. Ibrahim Aliyu TOL, Onankpa Ben. Prevalence and outcome of perinatal asphyxia: Our experience in a semi‑urban setting. Trop J Med Res 2017, 20:161–165.
11. Ilah B, Aminu M, Musa A, Adelakun M, Adeniji A, Kolawole T. Prevalence and Risk Factors for Perinatal Asphyxia as Seen at a Specialist Hospital in Gusau, Nigeria. Sub-Saharan African Journal of Medicine 2015, 2(2):64.
12. Mukhtar-Yola M, Audu LI, Olaniyan O, Akinbi HT, Dawodu A, Donovan EF. Decreasing birth asphyxia: utility of statistical process control in a low-resource setting. BMJ Open Qual 2018, 7(3):e000231. doi: 10.1136/bmjoq-2017-000231 30234170
13. Roba AA, Diro DH. Morbidities, Rate and Time Trends of Neonatal Mortality in Dilchora Referral Hospital, Dire Dawa, Ethiopia, 2012–2017. Austin Med Sci 2017, 2(1).
14. Ibrahim NA, Muhye A, Abdulie S. Prevalence of Birth Asphyxia and Associated Factors among Neonates Delivered in Dilchora Referral Hospital, in Dire Dawa, Eastern Ethiopia. Clinics Mother Child Health 2017, 14 (279). doi: 10.4172/2090-7214.1000279
15. Solayman M HS, Akber T, Islam MI, Islam MA. Prevalence of Perinatal Asphyxia with Evaluation of Associated Risk Factors in a Rural Tertiary Level Hospital. KYAMC Journal 2017, 8(1).
16. Aslam HM, Saleem S, Afzal R, Iqbal U, Saleem SM, Shaikh MW, et al. "Risk factors of birth asphyxia". Ital J Pediatr 2014, 40:94. doi: 10.1186/s13052-014-0094-2 25526846
17. Farhana Tabassum AR, Ariff Shabina, Soofi Sajid, Bhutta Zulfiqar A. Risk Factors Associated with Birth Asphyxia in Rural District Matiari, Pakistan: A Case Control Study. International Journal of Clinical Medicine 2014,5:1430–1441.
18. Anália Luana Sena de Souza NLdS, de França Débora Feitosa, de Oliveira Samara Isabela Maia, Araújo Anne Karoline Candido, Dantas Dândara Nayara Azevedo. Risk Factors for Perinatal Asphyxia in Newborns Delivered at Term. Open Journal of Nursing 2016, 6:558–564.
19. Tasew H, Zemicheal M, Teklay G, Mariye T, Ayele E. Risk factors of birth asphyxia among newborns in public hospitals of Central Zone, Tigray, Ethiopia. BMC Res Notes 2018, 11(1):496. doi: 10.1186/s13104-018-3611-3 30029614
20. World Health Organization. WHO recommendations on interventions to improve preterm birth outcome. France, 2015. Aavailable: https://www.who.int/reproductivehealth/publications/maternal_perinatal_health. accessed on February 3, 2018.
21. Federal Minstry of Health, JSI [Ethiopia]. (2009) Addressing Community Maternal and Neonatal Health in Ethiopia. Report from National Scoping Exercise and National Workshop to Increase Demand, Accesses and Use of Community Maternal and Neonatal Health Services. Addis Ababa, Ethiopia, 2009.
22. United Nations. the 2030 agenda for sustainable development, 2016. Available: https://www.un.org/sustainabledevelopment/blog/tag/2030-agenda-for-sustainable-development/, accessed on January 3, 2018.
23. Federal Minstry of Health [Ethiopia]. Health Sector Transformation Plan (HSTP 2016–2020). Addis Ababa, Ethiopia: FMOH, 2015.
24. Federal Minstry of Health [Ethiopia]. Neonatal Intensive Care Unit (NICU) Training: Management Protocol. Addis Ababa, Ethiopia; FMO, 2014.
25. Wayessa Zelalem Jebessa, Joseph Jophin. Birth asphyxia and associated factors among newborns delivered in Jimma zone public hospitals, Southwest Ethiopia: A cross-sectional study. Journal of Midwifery and Reproductive Health 2018, 6(2):1289–1295.
26. Ververs MT, Antierens A, Sackl A, Staderini N, Captier V. Which anthropometric indicators identify a pregnant woman as acutely malnourished and predict adverse birth outcomes in the humanitarian context? PLoS Curr 2015, 5.
27. Jonathan Izudi CE, Katawera Andrew, and Kekitiinwa Adeodata. Quality Improvement Interventions for Nutritional Assessment among Pregnant Mothers in Northeastern Uganda. Hindawi BioMed Research International 2017, Vol.2017.
28. Ricalde AE, Velasquez-Melendez G, Tanaka AC, de Siqueira AA. Mid-upper arm circumference in pregnant women and its relation to birth weight. Rev Saude Publica 2008, 32(2):112–117.
29. Batool AH, Zulfiqar A.B. Birth Asphyxia in Developing Countries: Current Status and Public Health Implications. Curr Probl Pediatr Adolesc Health Care, June 2006.
30. Demisse AG, Alemu F, Gizaw MA, Tigabu Z. Patterns of admission and factors associated with neonatal mortality among neonates admitted to the neonatal intensive care unit of University of Gondar Hospital, Northwest Ethiopia. Pediatric Health Med Ther 2017, 8:57–64. doi: 10.2147/PHMT.S130309 29388628
31. Debelew GT, Afework MF, Yalew AW. Determinants and Causes of Neonatal Mortality in Jimma Zone, Southwest Ethiopia: A Multilevel Analysis of Prospective Follow Up Study. PLoS ONE 2014, 9(9): e107184. doi: 10.1371/journal.pone.0107184 25232842
32. Orsido TT, Asseffa NA, Berheto TM. Predictors of Neonatal mortality in Neonatal intensive care unit at referral Hospital in Southern Ethiopia: a retrospective cohort study. BMC Pregnancy Childbirth 2019, 19(1):83. doi: 10.1186/s12884-019-2227-5 30819143
33. Federal Minstry of Health [Ethiopia]. National Newborn and Child Survival Strategy Document Brief Summary 2015/16-2019/20. FMOH, Addis Ababa, 2015.
34. Sfere WN, Yesuf A. Neonatal asphyxia and associated factors among neonates on labor ward at debre-tabor general hospital, Debre Tabor Town, South Gonder, North Centeral Ethiopia. Int J Pregn & Chi Birth 2018, 4(6):208–212. doi: 10.1038/sj.ijo.0803406
35. K Mumuni AS, Seffah JD. (2017) Birth Asphyxia among Term Neonates at Korle-Bu Teaching Hospital (KBTH) in Accra. Obstetrics & Gynecology International Journal 2017, 7(6).
36. Chiabi A NS, Mah E, Nodem S, Mbuagbaw L, Mbonda E, Tchokoteu PF, et al. Risk Factors for Birth Asphyxia in an Urban Health Facility in Cameroon. Iran J Child Neurol 2013, 7(3):46–54. 24665306
37. Onyiriuka AN. Birth Asphyxia in a Nigerian Mission Hospital in Benin City. Trop J Obstet Gynaecol 2009, 26(1).
38. Gillam-Krakauer M GJC. Birth Asphyxia. [Updated 2018]. In StatPearls [Internet] Treasure Island (FL): StatPearls Publishing, December 2, 2018.
39. Wosenu L, Worku AG, Teshome DF, Gelagay AA (2018) Determinants of birth asphyxia among live birth newborns in University of Gondar referral hospital, northwest Ethiopia: A case-control study. PLoS ONE 13(9): e0203763. doi: 10.1371/journal.pone.0203763 30192884
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