Real world, big data cost of pharmaceutical treatment for rheumatoid arthritis in Greece
Autoři:
Kyriakos Souliotis aff001; Christina Golna aff003; Chara Kani aff004; Sofia Nikolaidi aff002; Dimitrios Boumpas aff005
Působiště autorů:
Faculty of Social and Political Sciences, University of Peloponnese, Corinth, Greece
aff001; Health Policy Institute, Athens, Greece
aff002; Innowth Ltd, Larnaca, Cyprus
aff003; Medicines Division, National Organization for Healthcare Services Provision (EOPYY), Athens, Greece
aff004; Attikon University Hospital, National and Kapodistrian University of Athens, Athens, Greece
aff005
Vyšlo v časopise:
PLoS ONE 14(12)
Kategorie:
Research Article
prolekare.web.journal.doi_sk:
https://doi.org/10.1371/journal.pone.0226287
Souhrn
Introduction
Rheumatoid Arthritis (RA) is a highly prevalent autoimmune disease associated with joint inflammation and destruction. Treatment for RA, especially with biologic agents (biologics), improves patient functionality and quality of life and averts costly complications or disease progression. Cost of RA pharmaceutical treatment has rarely been reported on the basis of real-world, big data. This study reports on the real-world, big data RA pharmaceutical treatment cost in Greece.
Methods
The Business Intelligence database of the National Organization for Healthcare Services Provision (EOPYY) was used to identify and provide analytics on patients on treatment for RA. EOPYY is responsible for funding healthcare and pharmaceutical care services for approximately 95% of the population in the country. ICD-10 codes were applied to identify patients with RA and at least one reimbursed prescription between 1 June 2014 and 31 May 2015.
Results
35,873 unique patients were recorded as undergoing treatment for RA. Total reimbursed treatment cost for the study period was €81,206,363.70, of which €52,732,142.18 (64.94%) was for treatment with biologics. Of that cost, €39,724,489.71 (48.32%) accounted for treatment with anti-TNFs and/or methotrexate/corticosteroids.
Conclusion
Real world, big data analysis confirms that the major driver of RA pharmaceutical cost is, as expected, the cost of treatment with biologics. It is critical to be able to match this cost to the treatment outcome it produces to ensure an optimal, no-waste, evidence-based allocation of healthcare resources to need.
Klíčová slova:
Rheumatoid arthritis – Drug therapy – Age groups – Age distribution – Intelligence – NSAIDs – Methotrexate – Greece
Zdroje
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PLOS One
2019 Číslo 12
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